Vis enkel innførsel

dc.contributor.authorSletmoen, Marit
dc.contributor.authorGerken, Thomas A.
dc.contributor.authorStokke, Bjørn Torger
dc.contributor.authorBurchell, Joy
dc.contributor.authorBrewer, C. Fred
dc.date.accessioned2019-03-15T12:20:32Z
dc.date.available2019-03-15T12:20:32Z
dc.date.created2018-11-23T14:14:52Z
dc.date.issued2018
dc.identifier.citationGlycobiology. 2018, 28 (7), 437-442.nb_NO
dc.identifier.issn0959-6658
dc.identifier.urihttp://hdl.handle.net/11250/2590250
dc.description.abstractThe mucin-type O-glycome in cancer aberrantly expresses the truncated glycans Tn (GalNAcα1-Ser/Thr) and STn (Neu5Acα2,6GalNAcα1-Ser/Thr). However, the role of Tn and STn in cancer and other diseases is not well understood. Our recent discovery of the self-binding properties (carbohydrate–carbohydrate interactions, CCIs) of Tn (Tn–Tn) and STn (STn–STn) provides a model for their possible roles in cellular transformation. We also review evidence that Tn and STn are members of a larger family of glycan tumor antigens that possess CCIs, which may participate in oncogenesis.nb_NO
dc.language.isoengnb_NO
dc.publisherOxford University Pressnb_NO
dc.titleTn and STn are members of a family of carbohydrate tumor antigens that possess carbohydrate-carbohydrate interactionsnb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionacceptedVersionnb_NO
dc.source.pagenumber437-442nb_NO
dc.source.volume28nb_NO
dc.source.journalGlycobiologynb_NO
dc.source.issue7nb_NO
dc.identifier.doi10.1093/glycob/cwy032
dc.identifier.cristin1634320
dc.description.localcodeThis is a pre-copyedited, author-produced version of an article accepted for publication in Glycobiology following peer review. The version of record is available online at: https://doi.org/10.1093/glycob/cwy032nb_NO
cristin.unitcode194,66,15,0
cristin.unitcode194,66,20,0
cristin.unitnameInstitutt for bioteknologi og matvitenskap
cristin.unitnameInstitutt for fysikk
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode1


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel