dc.contributor.author | Hjort, Rebecka | |
dc.contributor.author | Ahlqvist, Emma | |
dc.contributor.author | Carlsson, Per-Ola | |
dc.contributor.author | Grill, Valdemar Erik Robert | |
dc.contributor.author | Groop, Leif | |
dc.contributor.author | Martinell, Mats | |
dc.contributor.author | Rasouli, Bahareh | |
dc.contributor.author | Rosengren, Anders | |
dc.contributor.author | Tuomi, Tiinamaija | |
dc.contributor.author | Åsvold, Bjørn Olav | |
dc.contributor.author | Carlsson, Sofia | |
dc.date.accessioned | 2019-03-14T07:34:20Z | |
dc.date.available | 2019-03-14T07:34:20Z | |
dc.date.created | 2018-07-02T13:21:44Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | Diabetologia. 2018, 61 (6), 1333-1343. | nb_NO |
dc.identifier.issn | 0012-186X | |
dc.identifier.uri | http://hdl.handle.net/11250/2589921 | |
dc.description.abstract | Aims/hypothesis
Excessive weight is a risk factor for type 2 diabetes, but its role in the promotion of autoimmune diabetes is not clear. We investigated the risk of latent autoimmune diabetes in adults (LADA) in relation to overweight/obesity in two large population-based studies.
Methods
Analyses were based on incident cases of LADA (n = 425) and type 2 diabetes (n = 1420), and 1704 randomly selected control participants from a Swedish case–control study and prospective data from the Norwegian HUNT Study including 147 people with LADA and 1,012,957 person-years of follow-up (1984–2008). We present adjusted ORs and HRs with 95% CI.
Results
In the Swedish data, obesity was associated with an increased risk of LADA (OR 2.93, 95% CI 2.17, 3.97), which was even stronger for type 2 diabetes (OR 18.88, 95% CI 14.29, 24.94). The association was stronger in LADA with low GAD antibody (GADA; | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | Springer Verlag | nb_NO |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | Overweight, obesity and the risk of LADA: results from a Swedish case-control study and the Norwegian HUNT Study | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | nb_NO |
dc.description.version | publishedVersion | nb_NO |
dc.source.pagenumber | 1333-1343 | nb_NO |
dc.source.volume | 61 | nb_NO |
dc.source.journal | Diabetologia | nb_NO |
dc.source.issue | 6 | nb_NO |
dc.identifier.doi | 10.1007/s00125-018-4596-0 | |
dc.identifier.cristin | 1595190 | |
dc.description.localcode | © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), | nb_NO |
cristin.unitcode | 194,65,15,0 | |
cristin.unitcode | 194,65,20,0 | |
cristin.unitname | Institutt for klinisk og molekylær medisin | |
cristin.unitname | Institutt for samfunnsmedisin og sykepleie | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |