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dc.contributor.authorHaug, Eirin
dc.contributor.authorHorn, Julie
dc.contributor.authorMarkovitz, Amanda Rose
dc.contributor.authorFraser, Abigail
dc.contributor.authorMacdonald-Wallis, Corrie
dc.contributor.authorTilling, Kate
dc.contributor.authorRomundstad, Pål Richard
dc.contributor.authorRich-Edwards, Janet Wilson
dc.contributor.authorÅsvold, Bjørn Olav
dc.identifier.citationEuropean Journal of Epidemiology. 2018, 1-11.nb_NO
dc.description.abstractThe drop in blood pressure during pregnancy may persist postpartum, but the impact of pregnancy on blood pressure across the life course is not known. In this study we examined blood pressure trajectories for women in the years preceding and following pregnancy and compared life course trajectories of blood pressure for parous and nulliparous women. We linked information on all women who participated in the population-based, longitudinal HUNT Study, Norway with pregnancy information from the Medical Birth Registry of Norway. A total of 23,438 women were included with up to 3 blood pressure measurements per woman. Blood pressure trajectories were compared using a mixed effects linear spline model. Before first pregnancy, women who later gave birth had similar mean blood pressure to women who never gave birth. Women who delivered experienced a drop after their first birth of − 3.32 mmHg (95% CI, − 3.93, − 2.71) and − 1.98 mmHg (95% CI, − 2.43, − 1.53) in systolic and diastolic blood pressure, respectively. Subsequent pregnancies were associated with smaller reductions. These pregnancy-related reductions in blood pressure led to persistent differences in mean blood pressure, and at age 50, parous women still had lower systolic (− 1.93 mmHg; 95% CI, − 3.33, − 0.53) and diastolic (− 1.36 mmHg; 95% CI, − 2.26, − 0.46) blood pressure compared to nulliparous women. The findings suggest that the first pregnancy and, to a lesser extent, successive pregnancies are associated with lasting and clinically relevant reductions in systolic and diastolic blood pressure.nb_NO
dc.rightsNavngivelse 4.0 Internasjonal*
dc.titleThe impact of parity on life course blood pressure trajectories: the HUNT study in Norwaynb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.source.journalEuropean Journal of Epidemiologynb_NO
dc.relation.projectNorges forskningsråd: 231149nb_NO
dc.description.localcode© The Author(s) 2018. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.nb_NO
cristin.unitnameInstitutt for samfunnsmedisin og sykepleie
cristin.unitnameHelseundersøkelsen i Nord-Trøndelag

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