dc.contributor.author | Skovlund, Eva | |
dc.contributor.author | Leufkens, HGM | |
dc.contributor.author | Smyth, JF | |
dc.date.accessioned | 2018-09-07T11:08:59Z | |
dc.date.available | 2018-09-07T11:08:59Z | |
dc.date.created | 2018-08-16T14:32:13Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | European Journal of Cancer. 2018, 101 69-76. | nb_NO |
dc.identifier.issn | 0959-8049 | |
dc.identifier.uri | http://hdl.handle.net/11250/2561458 | |
dc.description.abstract | Excitement about the dramatic increase in potential successful anticancer medicines in recent years is hampered by the high costs involved as well as the length of time traditional pathways take for regulatory approval. The translation of experimental clinical data into real-world evidence is also problematic. While the randomised controlled trial remains the gold standard for assessing efficacy and safety, there is increasing interest in the use of observational data to enable more rapid, informed and widespread availability and access to important anticancer medicines. Taking real-world evidence into account in regulatory and health technology assessment in a thoughtful and balanced fashion will enrich and justify sound decision-making. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | Elsevier | nb_NO |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/deed.no | * |
dc.title | The use of real world data in cancer drug development | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | nb_NO |
dc.description.version | acceptedVersion | nb_NO |
dc.source.pagenumber | 69-76 | nb_NO |
dc.source.volume | 101 | nb_NO |
dc.source.journal | European Journal of Cancer | nb_NO |
dc.identifier.doi | https://doi.org/10.1016/j.ejca.2018.06.036 | |
dc.identifier.cristin | 1602457 | |
dc.description.localcode | © 2018. This is the authors’ accepted and refereed manuscript to the article. Locked until 18.7.2019 due to copyright restrictions. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | nb_NO |
cristin.unitcode | 194,65,20,0 | |
cristin.unitname | Institutt for samfunnsmedisin og sykepleie | |
cristin.ispublished | false | |
cristin.fulltext | postprint | |
cristin.qualitycode | 1 | |