Simple generalized reaction conditions for the conversion of primary aliphatic amines to surfactant-like guanidine salts with 1H-pyrazole carboxamidine hydrochloride
Journal article
Submitted version
Date
2017Metadata
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Abstract
Improved reaction conditions for the electrophile reaction between a free aliphatic amine and 1H-pyrazole carboxamidine have been discovered. The surfactant-like guanidine salts, which are often hard to work with, were obtained in decent yield with short reaction times, minimal workup, and high level of purity.