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Simple generalized reaction conditions for the conversion of primary aliphatic amines to surfactant-like guanidine salts with 1H-pyrazole carboxamidine hydrochloride

Bakka, Thomas Aleksander; Gautun, Odd Reidar
Journal article
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URI
http://hdl.handle.net/11250/2493734
Date
2017
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Original version
Synthetic Communications. 2017, 47 (2), 169-172.   10.1080/00397911.2016.1257724
Abstract
Improved reaction conditions for the electrophile reaction between a free aliphatic amine and 1H-pyrazole carboxamidine have been discovered. The surfactant-like guanidine salts, which are often hard to work with, were obtained in decent yield with short reaction times, minimal workup, and high level of purity.
Publisher
Taylor & Francis
Journal
Synthetic Communications

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