dc.contributor.author | Lien, Sigbjørn | |
dc.contributor.author | Koop, Ben F | |
dc.contributor.author | Sandve, Simen Rød | |
dc.contributor.author | Miller, Jason R. | |
dc.contributor.author | Kent, Matthew Peter | |
dc.contributor.author | Nome, Torfinn | |
dc.contributor.author | Hvidsten, Torgeir Rhoden | |
dc.contributor.author | Leong, Jong | |
dc.contributor.author | Minkley, David R. | |
dc.contributor.author | Zimin, Aleksey | |
dc.contributor.author | Grammes, Fabian | |
dc.contributor.author | Grove, Harald | |
dc.contributor.author | Gjuvsland, Arne Bjørke | |
dc.contributor.author | Walenz, Brian | |
dc.contributor.author | Hermansen, Russell A. | |
dc.contributor.author | von Schalburg, Kristian R. | |
dc.contributor.author | Rondeau, Eric | |
dc.contributor.author | Genova, Alex Di | |
dc.contributor.author | Antony Samy, Jeevan Karloss | |
dc.contributor.author | Vik, Jon Olav | |
dc.contributor.author | Vigeland, Magnus Dehli | |
dc.contributor.author | Caler, Lis | |
dc.contributor.author | Grimholt, Unni | |
dc.contributor.author | Jentoft, Sissel | |
dc.contributor.author | Våge, Dag Inge | |
dc.contributor.author | de Jong, Pieter J. | |
dc.contributor.author | Moen, Thomas | |
dc.contributor.author | Baranski, Matthew | |
dc.contributor.author | Palti, Yniv | |
dc.contributor.author | Smith, Douglas W. | |
dc.contributor.author | Yorke, James A. | |
dc.contributor.author | Nederbragt, Alexander J. | |
dc.contributor.author | Tooming-Klunderud, Ave | |
dc.contributor.author | Jakobsen, Kjetill Sigurd | |
dc.contributor.author | Jiang, Xuanting | |
dc.contributor.author | Fan, Dingding | |
dc.contributor.author | Hu, Yan | |
dc.contributor.author | Liberles, David A. | |
dc.contributor.author | Vidal, Rodrigo | |
dc.contributor.author | Iturra, Patricia | |
dc.contributor.author | Jones, Steven J.M. | |
dc.contributor.author | Jonassen, Inge | |
dc.contributor.author | Maass, Alejandro | |
dc.contributor.author | Omholt, Stig William | |
dc.contributor.author | Davidson, William S | |
dc.date.accessioned | 2018-01-30T15:29:13Z | |
dc.date.available | 2018-01-30T15:29:13Z | |
dc.date.created | 2016-05-25T15:42:21Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | Nature. 2016, 533 (7602), 200-205. | nb_NO |
dc.identifier.issn | 0028-0836 | |
dc.identifier.uri | http://hdl.handle.net/11250/2480787 | |
dc.description.abstract | The whole-genome duplication 80 million years ago of the common ancestor of salmonids (salmonid-specific fourth vertebrate whole-genome duplication, Ss4R) provides unique opportunities to learn about the evolutionary fate of a duplicated vertebrate genome in 70 extant lineages. Here we present a high-quality genome assembly for Atlantic salmon (Salmo salar), and show that large genomic reorganizations, coinciding with bursts of transposon-mediated repeat expansions, were crucial for the post-Ss4R rediploidization process. Comparisons of duplicate gene expression patterns across a wide range of tissues with orthologous genes from a pre-Ss4R outgroup unexpectedly demonstrate far more instances of neofunctionalization than subfunctionalization. Surprisingly, we find that genes that were retained as duplicates after the teleost-specific whole-genome duplication 320 million years ago were not more likely to be retained after the Ss4R, and that the duplicate retention was not influenced to a great extent by the nature of the predicted protein interactions of the gene products. Finally, we demonstrate that the Atlantic salmon assembly can serve as a reference sequence for the study of other salmonids for a range of purposes. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | Nature Publishing Group | nb_NO |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | The Atlantic salmon genome provides insights into rediploidization | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | nb_NO |
dc.description.version | publishedVersion | nb_NO |
dc.source.pagenumber | 200-205 | nb_NO |
dc.source.volume | 533 | nb_NO |
dc.source.journal | Nature | nb_NO |
dc.source.issue | 7602 | nb_NO |
dc.identifier.doi | 10.1038/nature17164 | |
dc.identifier.cristin | 1357548 | |
dc.relation.project | Norges forskningsråd: 222378 | nb_NO |
dc.relation.project | Norges forskningsråd: 179569 | nb_NO |
dc.description.localcode | This work is licensed under a Creative Commons Attribution 4.0 International License. | nb_NO |
cristin.unitcode | 194,66,10,0 | |
cristin.unitname | Institutt for biologi | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 2A | |