Browsing Kavliinstitutt for nevrovitenskap by Document Types "Journal article"
Now showing items 1-20 of 221
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A critical period for antidepressant-induced acceleration of neuronal maturation in adult dentate gyrus
(Journal article; Peer reviewed, 2017)Selective serotonin reuptake inhibitors (SSRIs) are the most commonly used medications for mood and anxiety disorders, and adult neurogenesis in the dentate gyrus has been shown to be involved in the behavioral effects of ... -
A prefrontal-thalamo-hippocampal circuit for goal-directed spatial navigation
(Journal article; Peer reviewed, 2015)Spatial navigation requires information about the relationship between current and future positions. The activity of hippocampal neurons appears to reflect such a relationship, representing not only instantaneous position ... -
Accurate determination of marker location within whole-brain microscopy images
(Journal article; Peer reviewed, 2022) -
Action Representation in the Mouse Parieto-Frontal Network
(Peer reviewed; Journal article, 2020)The posterior parietal cortex (PPC) and frontal motor areas comprise a cortical network supporting goal-directed behaviour, with functions including sensorimotor transformations and decision making. In primates, this network ... -
Activation of the hypothalamic feeding centre upon visual prey detection
(Journal article; Peer reviewed, 2017)The visual system plays a major role in food/prey recognition in diurnal animals, and food intake is regulated by the hypothalamus. However, whether and how visual information about prey is conveyed to the hypothalamic ... -
Adaptive spike threshold dynamics associated with sparse spiking of hilar mossy cells are captured by a simple model
(Peer reviewed; Journal article, 2023)Hilar mossy cells (hMCs) in the dentate gyrus (DG) receive inputs from DG granule cells (GCs), CA3 pyramidal cells and inhibitory interneurons, and provide feedback input to GCs. Behavioural and in vivo recording experiments ... -
Age-Related Differences in Amygdala Activation Associated With Face Trustworthiness but No Evidence of Oxytocin Modulation
(Journal article; Peer reviewed, 2022) -
All-viral tracing of monosynaptic inputs to single birthdate-defined neurons in the intact brain
(Journal article; Peer reviewed, 2022) -
An event map of memory space in the hippocampus
(Journal article; Peer reviewed, 2016)The hippocampus has long been implicated in both episodic and spatial memory, however these mnemonic functions have been traditionally investigated in separate research strands. Theoretical accounts and rodent data suggest ... -
Architectural organization of ∼1,500-neuron modular minicolumnar disinhibitory circuits in healthy and Alzheimer's cortices
(Peer reviewed; Journal article, 2023)Acquisition of neuronal circuit architectures, central to understanding brain function and dysfunction, remains prohibitively challenging. Here I report the development of a simultaneous and sequential octuple-sexdecuple ... -
Architecture and Organization of Mouse Posterior Parietal Cortex Relative to Extrastriate Areas
(Journal article; Peer reviewed, 2018)The posterior parietal cortex (PPC) is a multifaceted region of cortex, contributing to several cognitive processes including sensorimotor integration and spatial navigation. Although recent years have seen a considerable ... -
Architecture of spatial circuits in the hippocampal region
(Journal article; Peer reviewed, 2014)The hippocampal region contains several principal neuron types, some of which show distinct spatial firing patterns. The region is also known for its diversity in neural circuits and many have attempted to causally relate ... -
Architecture of the entorhinal cortex A review of entorhinal anatomy in rodents with some comparative notes
(Journal article; Peer reviewed, 2017)The entorhinal cortex (EC) is the major input and output structure of the hippocampal formation, forming the nodal point in cortico-hippocampal circuits. Different division schemes including two or many more subdivisions ... -
Are the Neuroprotective Effects of Exercise Training Systemically Mediated?
(Journal article; Peer reviewed, 2019)To date there is no cure available for dementia, and the field calls for novel therapeutic targets. A rapidly growing body of literature suggests that regular endurance training and high cardiorespiratory fitness attenuate ... -
"Assaying sensory ciliopathies using calcium biosensor expression in zebrafish ciliated olfactory neurons"
(Journal article; Peer reviewed, 2018)Background Primary cilia mediate signal transduction by acting as an organizing scaffold for receptors, signalling proteins and ion channels. Ciliated olfactory sensory neurons (OSNs) organize olfactory receptors and ion ... -
Association cortical areas in the mouse contain a large population of fast-spiking GABAergic neurons that do not express parvalbumin
(Journal article; Peer reviewed, 2024)GABAergic neurons represent 10–15% of the neuronal population of the cortex but exert a powerful control over information flow in cortical circuits. The largest GABAergic class in the neocortex is represented by the ... -
Association of Klotho protein levels and KL-VS heterozygosity with Alzheimer disease and amyloid and tau burden
(Journal article; Peer reviewed, 2022) -
Associations between the number of children, age at childbirths and prevalence of chronic low back pain: the Nord- Trøndelag Health Study
(Peer reviewed; Journal article, 2020)Background Associations between childbirths and subsequent risk of low back pain (LBP) have not been clarified. Changes in sex hormone levels or lumbar posture during pregnancy may have an impact on LBP later in life. ... -
Behavior-dependent directional tuning in the human visual-navigation network
(Peer reviewed; Journal article, 2020)The brain derives cognitive maps from sensory experience that guide memory formation and behavior. Despite extensive efforts, it still remains unclear how the underlying population activity unfolds during spatial navigation ... -
Behavioral decomposition reveals rich encoding structure employed across neocortex in rats
(Peer reviewed; Journal article, 2023)The cortical population code is pervaded by activity patterns evoked by movement, but it remains largely unknown how such signals relate to natural behavior or how they might support processing in sensory cortices where ...