Blar i Kavliinstitutt for nevrovitenskap på tidsskrift "eLIFE"
Viser treff 1-16 av 16
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An event map of memory space in the hippocampus
(Journal article; Peer reviewed, 2016)The hippocampus has long been implicated in both episodic and spatial memory, however these mnemonic functions have been traditionally investigated in separate research strands. Theoretical accounts and rodent data suggest ... -
During hippocampal inactivation, grid cells maintain synchrony, even when the grid pattern is lost
(Journal article; Peer reviewed, 2019)The grid cell network in the medial entorhinal cortex (MEC) has been subject to thorough testing and analysis, and many theories for their formation have been suggested. To test some of these theories, we re-analyzed data ... -
Functional properties of stellate cells in medial entorhinal cortex layer II
(Journal article; Peer reviewed, 2018)Layer II of the medial entorhinal cortex (MEC) contains two principal cell types: pyramidal cells and stellate cells. Accumulating evidence suggests that these two cell types have distinct molecular profiles, physiological ... -
Grid-cell representations in mental simulation
(Journal article; Peer reviewed, 2016)Anticipating the future is a key motif of the brain, possibly supported by mental simulation of upcoming events. Rodent single-cell recordings suggest the ability of spatially tuned cells to represent subsequent locations. ... -
Gustatory-mediated avoidance of bacterial lipopolysaccharides via TRPA1 activation in Drosophila
(Journal article; Peer reviewed, 2016)Detecting pathogens and mounting immune responses upon infection is crucial for animal health. However, these responses come at a high metabolic price (McKean and Lazzaro, 2011, Kominsky et al., 2010), and avoiding pathogens ... -
Histological E-data Registration in rodent Brain Spaces
(Peer reviewed; Journal article, 2023)Recording technologies for rodents have seen huge advances in the last decade, allowing users to sample thousands of neurons simultaneously from multiple brain regions. This has prompted the need for digital tool kits to ... -
Interpreting wide-band neural activity using convolutional neural networks
(Peer reviewed; Journal article, 2021)Rapid progress in technologies such as calcium imaging and electrophysiology has seen a dramatic increase in the size and extent of neural recordings. Even so, interpretation of this data requires considerable knowledge ... -
Landmark-based spatial navigation across the human lifespan
(Journal article; Peer reviewed, 2023) -
Local projections of layer Vb-to-Va are more prominent in lateral than in medial entorhinal cortex
(Peer reviewed; Journal article, 2021)The entorhinal cortex, in particular neurons in layer V, allegedly mediate transfer of information from the hippocampus to the neocortex, underlying long-term memory. Recently, this circuit has been shown to comprise a ... -
Mapping sequence structure in the human lateral entorhinal cortex
(Journal article; Peer reviewed, 2019)Remembering event sequences is central to episodic memory and presumably supported by the hippocampal-entorhinal region. We previously demonstrated that the hippocampus maps spatial and temporal distances between events ... -
Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium
(Peer reviewed; Journal article, 2020)Compartmentalization of cellular signaling forms the molecular basis of cellular behavior. The primary cilium constitutes a subcellular compartment that orchestrates signal transduction independent from the cell body. ... -
Novel analytical tools reveal that local synchronization of cilia coincides with tissue-scale metachronal waves in zebrafish multiciliated epithelia
(Journal article; Peer reviewed, 2023) -
Origin and role of the cerebrospinal fluid bidirectional flow in the central canal
(Peer reviewed; Journal article, 2020)Circulation of the cerebrospinal fluid (CSF) contributes to body axis formation and brain development. Here, we investigated the unexplained origins of the CSF flow bidirectionality in the central canal of the spinal cord ... -
Postnatal development of retrosplenial projections to the parahippocampal region of the rat
(Journal article; Peer reviewed, 2016)The rat parahippocampal region (PHR) and retrosplenial cortex (RSC) are cortical areas important for spatial cognition. In PHR, head-direction cells are present before eye-opening, earliest detected in postnatal day (P)11 ... -
Rapid encoding of task regularities in the human hippocampus guides sensorimotor timing
(Peer reviewed; Journal article, 2022)The brain encodes the statistical regularities of the environment in a task-specific yet flexible and generalizable format. Here, we seek to understand this process by bridging two parallel lines of research, one centered ... -
Resting-state gamma-band power alterations in schizophrenia reveal E/I-balance abnormalities across illness-stages
(Journal article; Peer reviewed, 2018)We examined alterations in E/I-balance in schizophrenia (ScZ) through measurements of resting-state gamma-band activity in participants meeting clinical high-risk (CHR) criteria (n = 88), 21 first episode (FEP) patients ...