• Neuronal spreading and plaque induction of intracellular Aβ and its disruption of Aβ homeostasis 

      Roos, Tomas T; Garcia, Megg G; Martinsson, Isak; Mabrouk, Rana; Israelsson, Bodil; Deierborg, Tomas; Kobro-Flatmoen, Asgeir; Tanila, Heikki; Gouras, Gunnar K (Peer reviewed; Journal article, 2021)
      The amyloid-beta peptide (Aβ) is thought to have prion-like properties promoting its spread throughout the brain in Alzheimer's disease (AD). However, the cellular mechanism(s) of this spread remains unclear. Here, we show ...