• Loss of glutamate transporter eaat2a leads to aberrant neuronal excitability, recurrent epileptic seizures, and basal hypoactivity 

      Hotz, Adriana L.; Jamali, Ahmed; Rieser, Nicolas N.; Niklaus, Stephanie; Aydin, Ecem; Myren-Svelstad, Sverre; Lalla, Laetitia Noelle Patricia; Jurisch-Yaksi, Nathalie; Yaksi, Emre; Neuhauss, Stephan C.F. (Peer reviewed; Journal article, 2021)
      Astroglial excitatory amino acid transporter 2 (EAAT2, GLT-1, and SLC1A2) regulates the duration and extent of neuronal excitation by removing glutamate from the synaptic cleft. Hence, an impairment in EAAT2 function could ...
    • Past, present and future of zebrafish in epilepsy research 

      Yaksi, Emre; Jamali, Ahmed; Diaz Verdugo, Carmen; Jurisch-Yaksi, Nathalie (Journal article; Peer reviewed, 2021)
      Animal models contribute greatly to our understanding of brain development and function as well as its dysfunction in neurological diseases. Epilepsy research is a very good example of how animal models can provide us with ...