• Spatial representation – from medial entorhinal cortex to hippocampus 

      Miao, Chenglin (Doctoral thesis at NTNU;2015:226, Doctoral thesis, 2015)
      Grid cells in the medial entorhinal cortex (MEC) and place cells in the hippocampus are key elements of the brain's spatial representation system. These cell populations are the basic component of the circuit of spatial ...
    • Topography of Place Maps along the CA3-to-CA2 Axis of the Hippocampus 

      Lu, Li; Igarashi, Kei M; Witter, Menno; Moser, Edvard Ingjald; Moser, May-Britt (Journal article; Peer reviewed, 2015)
      We asked whether the structural heterogeneity of the hippocampal CA3-CA2 axis is reflected in how space is mapped onto place cells in CA3-CA2. Place fields were smaller and sharper in proximal CA3 than in distal CA3 and ...
    • Hippocampal Remapping after Partial Inactivation of the Medial Entorhinal Cortex 

      Miao, Chenglin; Cao, Qichen; Ito, Hiroshi; Yamahachi, Homare; Witter, Menno; Moser, May-Britt; Moser, Edvard Ingjald (Journal article; Peer reviewed, 2015)
      Hippocampal place cells undergo remapping when the environment is changed. The mechanism of hippocampal remapping remains elusive but spatially modulated cells in the medial entorhinal cortex (MEC) have been identified as ...
    • Correlations and functional connections in a population of grid cells 

      Dunn, Benjamin Adric; Mørreaunet, Maria; Roudi, Yasser (Journal article; Peer reviewed, 2015)
      We study the statistics of spike trains of simultaneously recorded grid cells in freely behaving rats. We evaluate pairwise correlations between these cells and, using a maximum entropy kinetic pairwise model (kinetic Ising ...
    • Neural patterns in the hippocampus 

      Alme, Charlotte Boermeester (Doctoral thesis at NTNU;2015:146, Doctoral thesis, 2015)
      Summary: Memories make us who we are. Personal memories are tightly coupled to space – we often remember what happened where and when. Accordingly, by investigating how spatial memories are represented in the rodent ...
    • Waxholm Space atlas of the rat brain hippocampal region: Three-dimensional delineations based on magnetic resonance and diffusion tensor imaging 

      Kjønigsen, Lisa Jannicke; Lillehaug, Sveinung; Bjaalie, Jan G.; Witter, Menno; Leergaard, Trygve Brauns (Journal article; Peer reviewed, 2015)
      Atlases of the rat brain are widely used as reference for orientation, planning of experiments, and as tools for assigning location to experimental data. Improved quality and use of magnetic resonance imaging (MRI) and ...
    • Evolutionary conserved brainstem circuits encode category, concentration and mixtures of taste 

      Vendrell-Llopis, Nuria; Yaksi, Emre (Journal article; Peer reviewed, 2015)
      Evolutionary conserved brainstem circuits are the first relay for gustatory information in the vertebrate brain. While the brainstem circuits act as our life support system and they mediate vital taste related behaviors, ...
    • Functional segregation in the rat hippocampalentorhinal circuit 

      Lu, Li (Doctoral thesis at NTNU;2015:201, Doctoral thesis, 2015)
      NORSK SAMMENDRAG: Hippocampus-entorhinal systemet spiller en viktig rolle i romlig navigasjon og episodisk hukommelse hos rotter. Stedceller i hippocampus kan kode både romlig og kontekstuell informasjon. Som populasjon ...
    • Insular Cortex Projections to Frontal and Parahippocampal Areas in the Rat 

      Mathiasen, Mathias Lysholt (Doctoral thesis at NTNU;2015:109, Doctoral thesis, 2015)
      Insular cortex er en struktur i hjernen som har avgjørende betydning for hjernens behandling av en rekke sensoriske inntrykk, og strukturen er også involvert i koding av emosjonelle og affektive tilstander. Den primære ...
    • Place cells, grid cells, and memory 

      Moser, May-Britt; Rowland, David Clayton; Moser, Edvard Ingjald (Journal article; Peer reviewed, 2015)
      The hippocampal system is critical for storage and retrieval of declarative memories, including memories for locations and events that take place at those locations. Spatial memories place high demands on capacity. Memories ...
    • A prefrontal-thalamo-hippocampal circuit for goal-directed spatial navigation 

      Ito, Hiroshi; Zhang, Sheng Jia; Witter, Menno; Moser, Edvard Ingjald; Moser, May-Britt (Journal article; Peer reviewed, 2015)
      Spatial navigation requires information about the relationship between current and future positions. The activity of hippocampal neurons appears to reflect such a relationship, representing not only instantaneous position ...
    • Methods for studying the zebrafish brain: Past, present and future 

      Wyatt, Cameron; Bartoszek, Ewelina; Yaksi, Emre (Journal article; Peer reviewed, 2015)
      The zebrafish (Danio rerio) is one of the most promising new model organisms. The increasing popularity of this amazing small vertebrate is evident from the exponentially growing numbers of research articles, funded projects ...
    • Interaction of nucleus reuniens and entorhinal cortex projections in hippocampal field CA1 of the rat 

      Dolleman-van der Weel, M. J.; Lopes da Silva, F.H.; Witter, Menno (Journal article; Peer reviewed, 2016)
      The nucleus reuniens (RE) and entorhinal cortex (EC) provide monosynaptic excitatory inputs to the apical dendrites of pyramidal cells and to interneurons with dendrites in stratum lacunosum moleculare (LM) of hippocampal ...
    • Ready, steady, go! Development of spatial representations in the rat 

      Kruge, Ingvild Ulsaker (Doctoral theses at NTNU;2016:320, Doctoral thesis, 2016)
      In mice and men, the hippocampal region is the central brain network for declarative memory and dynamic representation of location. Hippocampal place cells and entorhinal grid cells use head direction, border and speed ...
    • Gustatory-mediated avoidance of bacterial lipopolysaccharides via TRPA1 activation in Drosophila 

      Soldano, Alessia; Alpizar, Yeranddy A; Boonen, Brett; Franco, Luis; Lopez-Requena, Alejandro; Liu, Guangda; Mora, Natalia; Yaksi, Emre; Voets, Thomas; Vennekens, Rudi; Hassan, Bassem A; Talavera, Karel (Journal article; Peer reviewed, 2016)
      Detecting pathogens and mounting immune responses upon infection is crucial for animal health. However, these responses come at a high metabolic price (McKean and Lazzaro, 2011, Kominsky et al., 2010), and avoiding pathogens ...
    • An event map of memory space in the hippocampus 

      Deuker, Lorena; Bellmund, Jacob Lukas Sarid; Schröder, Tobias Navarro; Döller, Christian Fritz Andreas (Journal article; Peer reviewed, 2016)
      The hippocampus has long been implicated in both episodic and spatial memory, however these mnemonic functions have been traditionally investigated in separate research strands. Theoretical accounts and rodent data suggest ...
    • Selective chemical genetic inhibition of protein kinase C epsilon reduces ethanol consumption in mice 

      Maiya, Rajani; McMahon, Thomas; Wang, Dan; Kanter, Benjamin Richard; Gandhi, Dev; Chapman, Holly L; Miller, Jacklyn; Messing, Robert O (Journal article; Peer reviewed, 2016)
      Reducing expression or inhibiting translocation of protein kinase C epsilon (PKCε) prolongs ethanol intoxication and decreases ethanol consumption in mice. However, we do not know if this phenotype is due to reduced PKCε ...
    • Posterior parietal cortex of the rat: Architectural delineation and thalamic differentiation 

      Olsen, Grethe Mari; Witter, Menno (Journal article; Peer reviewed, 2016)
      This study refines the characterization of the rat parietal cortical domain in terms of cyto- and chemoarchitecture as well as thalamic connectivity. We recognize three subdivisions of the posterior parietal cortex (PPC), ...
    • Retrosplenial connectivity with the (para)hippocampal region 

      Sugar, Jørgen Larsen (Doctoral theses at NTNU;2016:244, Doctoral thesis, 2016)
      The hippocampal formation and parahippocampal region (HF-PHR) receives input from a variety of cortical and subcortical structures, and one of the cortical regions which are heavily interconnected with HF-PHR is the ...
    • Sparse model selection in the highly under-sampled regime 

      Bulso, Nicola; Marsili, Matteo; Roudi, Yasser (Journal article, 2016)
      We propose a method for recovering the structure of a sparse undirected graphical model when very few samples are available. The method decides about the presence or absence of bonds between pairs of variable by considering ...