Blar i Kavliinstitutt for nevrovitenskap på tittel
Viser treff 139-158 av 341
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Hippocampal-medial entorhinal circuit is differently organized along the dorsoventral axis in rodents
(Peer reviewed; Journal article, 2023)The general understanding of hippocampal circuits is that the hippocampus and the entorhinal cortex (EC) are topographically connected through parallel identical circuits along the dorsoventral axis. Our anterograde tracing ... -
The Hippocampus Maps Concept Space, Not Feature Space
(Peer reviewed; Journal article, 2020)The hippocampal formation encodes maps of space and a key question in neuroscience is whether its spatial coding principles also provide a universal metric for the organization of nonspatial, conceptual information. Previous ... -
Histological E-data Registration in rodent Brain Spaces
(Peer reviewed; Journal article, 2023)Recording technologies for rodents have seen huge advances in the last decade, allowing users to sample thousands of neurons simultaneously from multiple brain regions. This has prompted the need for digital tool kits to ... -
How does ALS pathology spread to affect healthy neurons? Recapitulation of disease progression in multi-nodal neural networks in vitro
(Master thesis, 2020)Amyotrofisk lateral sklerose (ALS) er en nevrodegenerativ sykdom som påvirker øvre og nedre motornevroner, hvilket fører til en gradvis lammelse av muskler og som til slutt resulterer i død på grunn av respirasjonssvikt. ... -
How the Brain's Navigation System Shapes Our Visual Experience
(Journal article; Peer reviewed, 2018)We explore the environment not only by navigating, but also by viewing our surroundings with our eyes. Here we review growing evidence that the mammalian hippocampal formation, extensively studied in the context of navigation ... -
Human hippocampal theta oscillations reflect sequential dependencies during spatial planning.
(Peer reviewed; Journal article, 2020)Movement-related theta oscillations in rodent hippocampus coordinate ‘forward sweeps’ of location-specific neural activity that could be used to evaluate spatial trajectories online. This raises the possibility that increases ... -
Identification of a neuronal population in the telencephalon essential for fear conditioning in zebrafish
(Journal article; Peer reviewed, 2018)Background Fear conditioning is a form of learning essential for animal survival and used as a behavioral paradigm to study the mechanisms of learning and memory. In mammals, the amygdala plays a crucial role in fear ... -
An immersive first-person navigation task for abstract knowledge acquisition
(Peer reviewed; Journal article, 2021)Advances in virtual reality (VR) technology have greatly benefited spatial navigation research. By presenting space in a controlled manner, changing aspects of the environment one at a time or manipulating the gain from ... -
Impact of altered Alkyladenine DNA glycosylase expression on hippocampal cytoarchitecture
(Master thesis, 2020)DNA damage can be caused through exposure to both exogenous and endogenous agents. Through by-products of physiological cellular processes neurons are constantly exposed to agents that can induce DNA base lesions. Base ... -
Increasing levels of wild-type CREB up-regulates several activity-regulated inhibitor of death (AID) genes and promotes neuronal survival
(Journal article; Peer reviewed, 2012)Background CREB (cAMP-response element binding protein) is the prototypical signal-regulated transcription factor. In neurons, it is the target of the synaptic activity-induced nuclear calcium-calcium/calmodulin dependent ... -
Inducing a mental context for associative memory formation with real-time fMRI neurofeedback
(Peer reviewed; Journal article, 2022)Memory, one of the hallmarks of human cognition, can be modified when humans voluntarily modulate neural population activity using neurofeedback. However, it is currently unknown whether neurofeedback can influence the ... -
Inhibiting the neuronal region with initial neurodegeneration: effects on neuropathology and behavior
(Master thesis, 2021)Alzheimers sykdom er nevrodegenerativ og progressiv, og den vanligste årsaken til demens. Til tross for at Alzheimers er en økende global helse- og sosioøkonomisk bekymring, er ingen effektiv kur eller behandling tilgjengelig. ... -
Inhibitory Connectivity Dominates the Fan Cell Network in Layer II of Lateral Entorhinal Cortex
(Journal article; Peer reviewed, 2018)Fan cells in layer II of the lateral entorhinal cortex (LEC) form a main component of the projection to the dentate gyrus, CA3 and CA2 of the hippocampal formation. This projection has a counterpart originating from stellate ... -
Inositol 1,4,5-trisphosphate receptor type 1 and calcium in synaptic vesicles: Possible roles in regulation of synaptic function
(Master thesis, 2022)Synaptisk signallering i hjernen er prosessen der et nevron kommuniserer med et annen ved vesikkeleksocytose av et kjemisk transmitterstoff, som binder seg til reseptorer i den postsynaptiske membranen. Synaptisk overføring ... -
Insights into the quantification and reporting of model-related uncertainty across different disciplines
(Peer reviewed; Journal article, 2022)Quantifying uncertainty associated with our models is the only way we can express how much we know about any phenomenon. Incomplete consideration of model-based uncertainties can lead to overstated conclusions with real-world ... -
Insular Cortex Projections to Frontal and Parahippocampal Areas in the Rat
(Doctoral thesis at NTNU;2015:109, Doctoral thesis, 2015)Insular cortex er en struktur i hjernen som har avgjørende betydning for hjernens behandling av en rekke sensoriske inntrykk, og strukturen er også involvert i koding av emosjonelle og affektive tilstander. Den primære ... -
Integrating time from experience in the lateral entorhinal cortex
(Journal article; Peer reviewed, 2018)The encoding of time and its binding to events are crucial for episodic memory, but how these processes are carried out in hippocampal–entorhinal circuits is unclear. Here we show in freely foraging rats that temporal ... -
Integration and Segregation of Emotion Regulation Networks in Aging A Graph Theoretical Analysis on Resting State fMRI from the Human Connectome Project - Aging
(Master thesis, 2023)Growing old is often accompanied by a number of physical and behavioral changes. This includes, how emotions are perceived and regulated, which changes across the lifespan. In fact, with increasing age we observe improved ... -
Integration of grid maps in merged environments
(Journal article; Peer reviewed, 2018)Natural environments are represented by local maps of grid cells and place cells that are stitched together. The manner by which transitions between map fragments are generated is unknown. We recorded grid cells while rats ... -
Interaction of nucleus reuniens and entorhinal cortex projections in hippocampal field CA1 of the rat
(Journal article; Peer reviewed, 2016)The nucleus reuniens (RE) and entorhinal cortex (EC) provide monosynaptic excitatory inputs to the apical dendrites of pyramidal cells and to interneurons with dendrites in stratum lacunosum moleculare (LM) of hippocampal ...