Blar i Kavliinstitutt for nevrovitenskap på tittel
Viser treff 129-148 av 343
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Growing gold nanostructures for shape-selective cellular uptake
(Journal article; Peer reviewed, 2018)With development in the synthesis of shape- and size-dependent gold (Au) nanostructures (NSs) and their applications in nanomedicine, one of the biggest challenges is to understand the interaction of these shapes with ... -
Gustatory-mediated avoidance of bacterial lipopolysaccharides via TRPA1 activation in Drosophila
(Journal article; Peer reviewed, 2016)Detecting pathogens and mounting immune responses upon infection is crucial for animal health. However, these responses come at a high metabolic price (McKean and Lazzaro, 2011, Kominsky et al., 2010), and avoiding pathogens ... -
Head direction maps remain stable despite grid map fragmentation
(Journal article; Peer reviewed, 2012)Areas encoding space in the brain contain both representations of position (place cells and grid cells) and representations of azimuth (head direction cells). Previous studies have already suggested that although grid cells ... -
Heterogeneity of network and coding states in mouse CA1 place cells
(Journal article; Peer reviewed, 2023) -
Hexadirectional coding of visual space in human entorhinal cortex
(Journal article; Peer reviewed, 2018)Entorhinal grid cells map the local environment, but their involvement beyond spatial navigation remains elusive. We examined human functional MRI responses during a highly controlled visual tracking task and show that ... -
Hexadirectional Modulation of High-Frequency Electrophysiological Activity in the Human Anterior Medial Temporal Lobe Maps Visual Space
(Journal article; Peer reviewed, 2018)Grid cells are one of the core building blocks of spatial navigation [1]. Single-cell recordings of grid cells in the rodent entorhinal cortex revealed hexagonal coding of the local environment during spatial navigation ... -
High-resolution structural analysis of layer II principal neurons in the entorhinal cortex
(Master thesis, 2021)Entorhinal cortex (EC), bestående av mediale entorhinal cortex (MEC) or lateral entorhinal cortex (LEC), mottar et rikt utvalg av kortikale signaler. Her formes og kodes signalene inn i et relevant «språk» før de, gjennom ... -
Hippocampal Remapping after Partial Inactivation of the Medial Entorhinal Cortex
(Journal article; Peer reviewed, 2015)Hippocampal place cells undergo remapping when the environment is changed. The mechanism of hippocampal remapping remains elusive but spatially modulated cells in the medial entorhinal cortex (MEC) have been identified as ... -
Hippocampal spike‐time correlations and place field overlaps during open field foraging
(Journal article; Peer reviewed, 2019)Phase precessing place cells encode spatial information on fine timescales via the timing of their spikes. This phase code has been extensively studied on linear tracks and for short runs in the open field. However, less ... -
Hippocampal theta phases organize the reactivation of large-scale electrophysiological representations during goal-directed navigation
(Peer reviewed; Journal article, 2019)Humans are adept in simultaneously following multiple goals, but the neural mechanisms for maintaining specific goals and distinguishing them from other goals are incompletely understood. For short time scales, working ... -
Hippocampal-medial entorhinal circuit is differently organized along the dorsoventral axis in rodents
(Peer reviewed; Journal article, 2023)The general understanding of hippocampal circuits is that the hippocampus and the entorhinal cortex (EC) are topographically connected through parallel identical circuits along the dorsoventral axis. Our anterograde tracing ... -
The Hippocampus Maps Concept Space, Not Feature Space
(Peer reviewed; Journal article, 2020)The hippocampal formation encodes maps of space and a key question in neuroscience is whether its spatial coding principles also provide a universal metric for the organization of nonspatial, conceptual information. Previous ... -
Histological E-data Registration in rodent Brain Spaces
(Peer reviewed; Journal article, 2023)Recording technologies for rodents have seen huge advances in the last decade, allowing users to sample thousands of neurons simultaneously from multiple brain regions. This has prompted the need for digital tool kits to ... -
How does ALS pathology spread to affect healthy neurons? Recapitulation of disease progression in multi-nodal neural networks in vitro
(Master thesis, 2020)Amyotrofisk lateral sklerose (ALS) er en nevrodegenerativ sykdom som påvirker øvre og nedre motornevroner, hvilket fører til en gradvis lammelse av muskler og som til slutt resulterer i død på grunn av respirasjonssvikt. ... -
How the Brain's Navigation System Shapes Our Visual Experience
(Journal article; Peer reviewed, 2018)We explore the environment not only by navigating, but also by viewing our surroundings with our eyes. Here we review growing evidence that the mammalian hippocampal formation, extensively studied in the context of navigation ... -
Human hippocampal theta oscillations reflect sequential dependencies during spatial planning.
(Peer reviewed; Journal article, 2020)Movement-related theta oscillations in rodent hippocampus coordinate ‘forward sweeps’ of location-specific neural activity that could be used to evaluate spatial trajectories online. This raises the possibility that increases ... -
Identification of a neuronal population in the telencephalon essential for fear conditioning in zebrafish
(Journal article; Peer reviewed, 2018)Background Fear conditioning is a form of learning essential for animal survival and used as a behavioral paradigm to study the mechanisms of learning and memory. In mammals, the amygdala plays a crucial role in fear ... -
An immersive first-person navigation task for abstract knowledge acquisition
(Peer reviewed; Journal article, 2021)Advances in virtual reality (VR) technology have greatly benefited spatial navigation research. By presenting space in a controlled manner, changing aspects of the environment one at a time or manipulating the gain from ... -
Impact of altered Alkyladenine DNA glycosylase expression on hippocampal cytoarchitecture
(Master thesis, 2020)DNA damage can be caused through exposure to both exogenous and endogenous agents. Through by-products of physiological cellular processes neurons are constantly exposed to agents that can induce DNA base lesions. Base ... -
Increasing levels of wild-type CREB up-regulates several activity-regulated inhibitor of death (AID) genes and promotes neuronal survival
(Journal article; Peer reviewed, 2012)Background CREB (cAMP-response element binding protein) is the prototypical signal-regulated transcription factor. In neurons, it is the target of the synaptic activity-induced nuclear calcium-calcium/calmodulin dependent ...