Browsing Institutt for sirkulasjon og bildediagnostikk by Journals "BMJ Open"
Now showing items 1-20 of 30
-
A randomised controlled study of the long-term effects of exercise training on mortality in elderly people: Study protocol for the generation 100 study
(Journal article; Peer reviewed, 2015)Introduction: Epidemiological studies suggest that exercise has a tremendous preventative effect on morbidity and premature death, but these findings need to be confirmed by randomised trials. Generation 100 is a randomised, ... -
Acute kidney injury in patients with COVID-19 in the intensive care unit: Evaluation of risk factors and mortality in a national cohort
(Peer reviewed; Journal article, 2022)Objectives Acute kidney injury (AKI) is a frequent complication among critical ill patients with COVID-19, but the actual incidence is unknown as AKI-incidence varies from 25% to 89% in intensive care unit (ICU) populations. ... -
Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors?
(Journal article; Peer reviewed, 2015)Objectives: Opioids modulate the perception of breathlessness with a considerable variation in response, with poor correlation between the required opioid dose and symptom severity. The objective of this hypothesis-generating, ... -
Can video communication in the emergency medical communication centre improve dispatch precision? A before-after study in Norwegian helicopter emergency medical services
(Journal article; Peer reviewed, 2023)Abstract Objectives Dispatching helicopter emergency medical services (HEMS) to the patients with the greatest medical or logistical benefit remains challenging. The introduction of video calls (VC) in the emergency medical ... -
Cardiac arrest as a reportable condition: A cohort study of the first 6 years of the Norwegian out-of-hospital cardiac arrest registry
(Peer reviewed; Journal article, 2020)Objectives The Norwegian Cardiac Arrest Registry (NorCAR) was established in 2013 when cardiac arrest became a mandatory reportable condition. The aim of this cohort study is to describe how the world’s first mandatory, ... -
Cardiopulmonary and muscular effects of different doses of high-intensity physical training in substance use disorder patients: study protocol for a block allocated controlled endurance and strength training trial in an inpatient setting
(Peer reviewed; Journal article, 2022)Introduction Patients with substance use disorder (SUD) have high prevalence of lifestyle-related comorbidities. Physical exercise is known to yield substantial prophylactic impact on disease and premature mortality, and ... -
Changes in drug disposition of lithium during pregnancy: A retrospective observational study of patient data from two routine therapeutic drug monitoring services in Norway
(Journal article; Peer reviewed, 2017)Objectives Pregnancy may cause changes in drug disposition, dose requirements and clinical response. For lithium, changes in disposition during pregnancy have so far been explored in a single-dose study on 4 participants ... -
A clinical risk score to predict in-hospital mortality in critically ill patients with COVID-19: A retrospective cohort study
(Peer reviewed; Journal article, 2021)Objectives To identify factors influencing the mortality risk in critically ill patients with COVID-19, and to develop a risk prediction score to be used at admission to intensive care unit (ICU). Design A multicentre ... -
Dietary and/or physical activity interventions in women with overweight or obesity prior to fertility treatment: protocol for a systematic review and individual participant data meta-analysis
(Peer reviewed; Journal article, 2022)Introduction Dietary and/or physical activity interventions are often recommended for women with overweight or obesity as the first step prior to fertility treatment. However, randomised controlled trials (RCTs) so far ... -
Effects of a workplace exercise intervention on cardiometabolic health: Study protocol for a randomised controlled trial
(Peer reviewed; Journal article, 2021)Introduction The worldwide rising levels of physical inactivity especially in the United Arab Emirates (UAE) and the Eastern Mediterranean region are alarming. The UAE reports one of the highest rates of non-communicable ... -
Effects of external inspections on sepsis detection and treatment: a stepped-wedge study With cluster-level randomisation
(Peer reviewed; Journal article, 2020)Objective To evaluate the effects of external inspections on (1) hospital emergency departments’ clinical processes for detecting and treating sepsis and (2) length of hospital stay and 30-day mortality. Design Incomplete ... -
Effects of supervised exercise training during pregnancy on psychological well-being among overweight and obese women: secondary analyses of the ETIP-trial, a randomised controlled trial
(Journal article; Peer reviewed, 2019)Objectives Women with high body mass index (BMI) have increased risk for symptoms of anxiety and depression during pregnancy and postpartum. In this prespecified secondary analysis from the exercise training in pregnancy ... -
Efficacy and safety of 4 weeks' treatment with combined fluticasone furoate/vilanterol in a single inhaler given once daily in COPD: a placebo-controlled randomised trial
(Journal article; Peer reviewed, 2012)Background: Fluticasone furoate/vilanterol (FF/VI) is a novel once-daily (OD) inhaled corticosteroid/long-acting β2 agonist combination in development for chronic obstructive pulmonary disease (COPD) and asthma. Trial ... -
Improving reproductive function in women with polycystic ovary syndrome with high-intensity interval training (IMPROV-IT): study protocol for a two-centre, three-armed randomised controlled trial.
(Journal article; Peer reviewed, 2020)Introduction Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age and the leading cause of anovulatory infertility. Women with PCOS have a 15-fold higher prevalence of infertility, ... -
Injury Prevention and long-term Outcomes following Trauma - The IPOT project: a protocol for prospective nationwide registry-based studies in Norway
(Peer reviewed; Journal article, 2021)Introduction Traumatic injuries constitute a major cause of mortality and morbidity. Still, the public health burden of trauma in Norway has not been characterised using nationwide registry data. More knowledge is warranted ... -
Isolated and combined effects of high-intensity interval training and time-restricted eating on glycaemic control in reproductive-aged women with overweight or obesity: Study protocol for a four-armed randomised controlled trial
(Peer reviewed; Journal article, 2021)Introduction Overweight and obesity in reproductive aged women is a global problem due to the increased risk of subfertility, pregnancy complications and cardiometabolic diseases. High-intensity interval training and ... -
Light-moderate alcohol consumption and left ventricular function among healthy, middle-aged adults: the HUNT study
(Journal article; Peer reviewed, 2018)Objectives To investigate the association between alcohol consumption and left ventricular (LV) function in a population with low average alcohol intake. Design, setting and participants A total of 1296 healthy participants, ... -
Long-term temporal trends in incidence rate and case fatality of sepsis and COVID-19-related sepsis in Norwegian hospitals, 2008-2021: a nationwide registry study
(Peer reviewed; Journal article, 2023)Objectives To estimate temporal trends in incidence rate (IR) and case fatality during a 14-year period from 2008 to 2021, and to assess possible shifts in these trends during the COVID-19 pandemic. Setting All Norwegian ... -
Myocardial function in premature infants: a longitudinal observational study
(Journal article; Peer reviewed, 2013)Objectives: Gestational and chronological age may have an impact on myocardial function. We studied the longitudinal changes of the atrioventricular tissue Doppler velocities in premature infants through the neonatal ... -
Myocardial performance assessment in neonates by one-segment strain and strain rate analysis by tissue Doppler - a quality improvement cohort study
(Journal article; Peer reviewed, 2012)Objectives: To investigate one-segment strain and strain rate indices as measures of myocardial performance in asphyxiated term neonates. Design: Quality improvement cohort study. Setting: Newborns admitted to ...