Blar i Institutt for sirkulasjon og bildediagnostikk på forfatter "Sandvig, Axel"
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Effects of neural stem cell and olfactory ensheathing cell co-transplants on tissue remodelling after transient focal cerebral ischemia in the adult rat
Augestad, Ingrid Lovise; Nyman, Axel Karl Gottfrid; Costa, Alex Ignatius; Barnett, Susan Carol; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna (Journal article; Peer reviewed, 2017)Effective transplant-mediated repair of ischemic brain lesions entails extensive tissue remodeling, especially in the ischemic core. Neural stem cells (NSCs) are promising reparative candidates for stroke induced lesions, ... -
L-DOPA-Coated Manganese Oxide Nanoparticles as Dual MRI Contrast Agents and Drug-Delivery Vehicles
McDonagh, Birgitte Hjelmeland; Singh, Gurvinder; Hak, Sjoerd; Bandyopadhyay, Sulalit; Augestad, Ingrid Lovise; Peddis, Davide; Sandvig, Ioanna; Sandvig, Axel; Glomm, Wilhelm (Journal article; Peer reviewed, 2016)Manganese oxide nanoparticles (MONPs) are capable of time-dependent magnetic resonance imaging contrast switching as well as releasing a surface-bound drug. MONPs give T2/T2* contrast, but dissolve and release T1-active ... -
Labelling of olfactory ensheathing cells with micron-sized particles of iron oxide and detection by MRI
Sandvig, Ioanna; Hoang, Linh; Sardella, Thomas CP; Barnett, SC; Brekken, Christian; Tvedt, Kåre; Berry, Martin; Haraldseth, Olav; Sandvig, Axel; Thuen, Marte (Journal article; Peer reviewed, 2012)A crucial issue in transplant‐mediated repair of the damaged central nervous system (CNS) is serial non‐invasive imaging of the transplanted cells, which has led to interest in the application of magnetic resonance imaging ... -
Nanoparticle delivery to the brain - By focused ultrasound and self-assembled nanoparticle-stabilized microbubbles
Åslund, Andreas; Berg, Sigrid; Hak, Sjoerd; Mørch, Ýrr Asbjørg; Torp, Sverre Helge; Sandvig, Axel; Widerøe, Marius; Hansen, Rune; Davies, Ruth Catharina de Lange (Journal article, 2015)The blood–brain barrier (BBB) constitutes a significant obstacle for the delivery of drugs into the central nervous system (CNS). Nanoparticles have been able to partly overcome this obstacle and can thus improve drug ... -
Nanoparticle Mediated P-Glycoprotein Silencing for Improved Drug Delivery across the Blood-Brain Barrier: A siRNA-Chitosan Approach
Malmo, Jostein; Sandvig, Axel; Vårum, Kjell Morten; Strand, Sabina P. (Journal article; Peer reviewed, 2013)Background: Neonatal intermittent hyperoxia-hypoxia (IHH) is involved in the pathogenesis of retinopathy of prematurity. Whether similar oxygen fluctuations will create pathological changes in the grey and white matter ... -
Synthesis and in vitro cellular interactions of superparamagnetic iron nanoparticles with a crystalline gold shell
Bandyopadhyay, Sulalit; Singh, Gurvinder; Sandvig, Ioanna; Sandvig, Axel; Mathieu, Roland; Kumar, P Anil; Glomm, Wilhelm (Journal article; Peer reviewed, 2014)Fe@Au core–shell nanoparticles (NPs) exhibit multiple functionalities enabling their effective use in applications such as medical imaging and drug delivery. In this work, a novel synthetic method was developed and optimized ...