Blar i Institutt for sirkulasjon og bildediagnostikk på forfatter "Damås, Jan Kristian"
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Inflammatory Markers and Radiotherapy Response in Patients With Painful Bone Metastases
Habberstad, Ragnhild H; Aass, Nina Kathrine; Mollnes, Tom Eirik; Damås, Jan Kristian; Brunelli, Cinzia; Rossi, Romina; Garcia-Alonso, Elena; Kaasa, Stein; Klepstad, Pål (Peer reviewed; Journal article, 2022)Context Inflammation is proposed to influence tumor response in radiotherapy (RT). Clinical studies to investigate the relationship between inflammatory markers and RT response is warranted to understand the variable RT ... -
The inflammatory response is related to circulatory failure after out-of-hospital cardiac arrest: A prospective cohort study
Langeland, Halvor Johannes Breivik; Damås, Jan Kristian; Mollnes, Tom Eirik; Ludviksen, Judith K; Ueland, Thor; Michelsen, Annika Elisabet; Løberg, Magnus; Bergum, Daniel; Nordseth, Trond; Skjærvold, Nils Kristian; Klepstad, Pål (Peer reviewed; Journal article, 2021)Background: Whole body ischemia and reperfusion injury after cardiac arrest leads to the massive inflammation clinically manifested in the post-cardiac arrest syndrome. Previous studies on the inflammatory effect on ... -
Insomnia symptoms and risk of bloodstream infections: prospective data from the prospective population-based Nord-Trøndelag Health Study (HUNT), Norway
Thorkildsen, Marianne Thorkildsen; Laugsand, Lars Erik; Nilsen, Tom Ivar Lund; Mohus, Randi Marie; Hovik, Lise; Rogne, Tormod; Solligård, Erik; Damås, Jan Kristian; Gustad, Lise Tuset (Journal article; Peer reviewed, 2022) -
Interleukin-6 inhibition in ST-elevation myocardial infarction: Immune cell profile in the randomised ASSAIL-MI trial
Huse, Camilla; Anstensrud, Anne Kristine; Michelsen, Annika Elisabet; Ueland, Thor; Broch, Kaspar; Woxholt, Sindre; Yang, Kuan; Sharma, Kapil Kishore; Tøllefsen, Ingvild Maria; Bendz, Bjørn; Amundsen, Brage H.; Damås, Jan Kristian; Berg, Erlend Sturle; Bjørkelund, Elisabeth; Quiles-Jiménez, Ana M T; Bjerkeli, Vigdis; Bendz, Christina; Kleveland, Ola; Stensæth, Knut Haakon; Opdahl, Anders; Kløw, Nils-Einar; Andersen, Geir Øystein; Wiseth, Rune; Halvorsen, Bente; Gullestad, Lars; Seljeflot, Ingebjørg; Aukrust, Pål; Osnes, Liv T. N.; Dahl, Tuva Børresdatter (Peer reviewed; Journal article, 2022)We recently showed that interleukin (IL)-6 inhibition by tocilizumab improves myocardial salvage in ST-elevation myocardial infarction (STEMI). However, the mechanisms for this effect are not clear. Methods In this ... -
Interleukin-6 receptor inhibition in non-ST-elevation myocardial infarction - Results from a randomized clinical trial
Kleveland, Ola (Doctoral theses at NTNU;2019:50, Doctoral thesis, 2019)Norsk sammenfatning: Inhibering av interleukin-6 ved hjerteinfarkt uten ST-segment elevasjon i EKG. Resultater fra en randomisert klinisk studie. Dette arbeidet inneholder resultater fra en klinisk, randomisert, ... -
Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction
Kleveland, Ola; Ueland, Thor; Kunszt, Gabor; Bratlie, Marte; Yndestad, Arne; Broch, Kaspar; Holte, Espen; Ryan, Liv; Amundsen, Brage H.; Bendz, Bjørn; Aakhus, Svend; Espevik, Terje; Halvorsen, Bente; Mollnes, Tom Eirik; Wiseth, Rune; Gullestad, Lars; Aukrust, Pål; Damås, Jan Kristian (Journal article; Peer reviewed, 2018)Aim To evaluate the effect of interleukin-6 inhibition with tocilizumab on the cytokine network in patients with acute non-ST-elevation myocardial infarction (NSTEMI). Methods 117 patients with acute NSTEMI were randomised ... -
Iron and sex matter in severe infections Epidemiological studies of bloodstream infections, sepsis and COVID-19
Mohus, Randi Marie (Doctoral theses at NTNU;2022:360, Doctoral thesis, 2022) -
Iron status and the risk of sepsis and severe COVID-19: a two-sample Mendelian randomization study
Mohus, Randi Marie; Flatby, Helene Marie; Liyanarachi, Kristin Vardheim; DeWan, Andrew T.; Solligård, Erik; Damås, Jan Kristian; Åsvold, Bjørn Olav; Gustad, Lise Tuset; Rogne, Tormod (Journal article; Peer reviewed, 2022) -
Kodepraksis ved sepsis 2008–21
Skei, Nina Vibeche; Afset, Jan Egil; Ehrnström, Anna Greta Birgitta; Nessan, Bente Sofie; Damås, Jan Kristian; Nilsen, Tom Ivar Lund; Gustad, Lise Tuset (Journal article; Peer reviewed, 2024)Bakgrunn:Sepsis har høy insidens og mortalitet. For planlegging av helsetjenester og i forskning trengs presise data, og det er behov for å kartlegge kodepraksis i Norge. Materiale og metode: Alle personer over 17 år som ... -
Long-term temporal trends in incidence rate and case fatality of sepsis and COVID-19-related sepsis in Norwegian hospitals, 2008-2021: a nationwide registry study
Skei, Nina Vibeche; Nilsen, Tom Ivar Lund; Knoop, Siri Tandberg; Prescott, Hallie; Lydersen, Stian; Mohus, Randi Marie; Brkic, Alen; Liyanarachi, Kristin Vardheim; Solligård, Erik; Damås, Jan Kristian; Gustad, Lise Tuset (Peer reviewed; Journal article, 2023)Objectives To estimate temporal trends in incidence rate (IR) and case fatality during a 14-year period from 2008 to 2021, and to assess possible shifts in these trends during the COVID-19 pandemic. Setting All Norwegian ... -
Monitoring quality of care for peripheral intravenous catheters; feasibility and reliability of the peripheral intravenous catheters mini questionnaire (PIVC-miniQ)
Høvik, Lise Husby; Gjeilo, Kari Hanne; Lydersen, Stian; Rickard, Claire; Røtvold, Benedikte; Damås, Jan Kristian; Solligård, Erik; Gustad, Lise (Journal article; Peer reviewed, 2019)Background Peripheral intravenous catheters (PIVCs) account for a mean of 38% of catheter associated bloodstream infections (CABSI) with Staphylococcus aureus, which are preventable if deficiencies in best practice are ... -
Mycotic abdominal aortic aneurysm caused by Borrelia afzelii: a case report
Torsteinsen, Magne; Nilsen, Hans-Johnny; Damås, Jan Kristian; Stensvåg, Dordi; Nyrønning, Linn Ålstedt; Bergh, Kåre (Peer reviewed; Journal article, 2022)Background Inflammatory aneurysms and mycotic aneurysms make up a minority of abdominal aortic aneurysms. Mainly autoimmune mechanisms are proposed in the pathogenesis of inflammatory aneurysms, and it is not routine ... -
Novel Insights Into the Effects of Interleukin 6 Antagonism in Non-ST-Segment-Elevation Myocardial Infarction Employing the SOMAscan Proteomics Platform
George, Marc J; Kleveland, Ola; Garcia-Hernandez, Jorge; Palmen, Jutta; Lovering, Ruth; Wiseth, Rune; Aukrust, Pål; Engmann, Jorgen; Damås, Jan Kristian; Hingorani, Aroon D; Gullestad, Lars; Casas, Juan P; Ueland, Thor (Peer reviewed; Journal article, 2020)Background Interleukin 6 concentration is associated with myocardial injury, heart failure, and mortality after myocardial infarction. In the Norwegian tocilizumab non-ST-segment-elevation myocardial infarction trial, the ... -
Pharmacologic and Genetic Downregulation of Proprotein Convertase Subtilisin/Kexin Type 9 and Survival from Sepsis
Lawler, Patrick R.; Manvelian, Garen; Coppi, Alida; Damask, Amy; Cantor, Michael N.; Ferreira, Manuel A. R.; Paulding, Charles; Banerjee, Nilanjana; Li, Dadong; Jorgensen, Susan; Attre, Richa; Carey, David J.; Krebs, Kristine; Milani, Lili; Hveem, Kristian; Damås, Jan Kristian; Solligård, Erik; Stender, Stefan; Tybjærg-Hansen, Anne; Nordestgaard, Børge G.; Hernandez-Beeftink, Tamara; Rogne, Tormod; Flores Perez, Carlos Antonio; Villar, Jesús; Walley, Keith R.; Liu, Vincent X.; Fohner, Alison E.; Lotta, Luca A.; Kyratsous, Christos A.; Sleeman, Mark W.; Scemama, Michel; Delgizzi, Richard; Pordy, Robert; Horowitz, Julie E.; Baras, Aris; Martin, Greg S.; Steg, Philippe Gabriel; Schwartz, Gregory G.; Szarek, Michael; Goodman, Shaun G. (Peer reviewed; Journal article, 2023)OBJECTIVES: Treatments that prevent sepsis complications are needed. Circulating lipid and protein assemblies—lipoproteins play critical roles in clearing pathogens from the bloodstream. We investigated whether early ... -
Poor performance of quick-SOFA (qSOFA) score in predicting severe sepsis and mortality: a prospective study of patients admitted with infection to the emergency department
Askim, Åsa Susanne; Moser, Florentin; Gustad, Lise; Stene, Helga; Gundersen, Maren; Åsvold, Bjørn Olav; Dale, Jostein; Bjørnsen, Lars Petter Bache-Wiig; Damås, Jan Kristian; Solligård, Erik (Journal article; Peer reviewed, 2017)Background We aimed to evaluate the clinical usefulness of qSOFA as a risk stratification tool for patients admitted with infection compared to traditional SIRS criteria or our triage system; the Rapid Emergency Triage ... -
Presenting complaints and mortality in a cohort of 22 000 adult emergency patients at a local hospital in Nepal
Giri, Samita; Rogne, Tormod; Uleberg, Oddvar; Skovlund, Eva; Shrestha, Sanu Krishna; Koju, Rajendra; Damås, Jan Kristian; Solligård, Erik; Risnes, Kari R (Journal article; Peer reviewed, 2019)Background There is a need to develop sustainable emergency health care systems in low-resource settings, but data that analyses emergency health care needs in these settings are scarce. We aimed at assessing presenting ... -
Prior statin use and 90-day mortality in Gram-negative and Gram-positive bloodstream infection: a prospective observational study
Mehl, Arne; Harthug, Stig; Lydersen, Stian; Paulsen, Julie; Åsvold, Bjørn Olav; Solligård, Erik; Damås, Jan Kristian; Edna, Tom-Harald (Journal article; Peer reviewed, 2014)n several studies on patients with bloodstream infection (BSI), prior use of statins has been associated with improved survival. Gram-positive and Gram-negative bacteria alert the innate immune system in different ways. ... -
Randomized Trial of Interleukin-6 Receptor Inhibition in Patients With Acute ST-Segment Elevation Myocardial Infarction
Broch, Kaspar; Anstensrud, Anne Kristine; Woxholt, Sindre; Sharma, Kapil Kishore; Tøllefsen, Ingvild Maria; Bendz, Bjørn; Aakhus, Svend; Ueland, Thor; Amundsen, Brage H.; Damås, Jan Kristian; Berg, Erlend; Bjørkelund, Elisabeth; Bendz, Christina; Hopp, Einar; Kleveland, Ola; Stensæth, Knut Haakon; Opdahl, Anders; Kløw, Nils-Einar; Seljeflot, Ingebjørg; Andersen, Geir Øystein; Wiseth, Rune; Aukrust, Pål; Gullestad, Lars (Journal article; Peer reviewed, 2021)Background - Prompt myocardial revascularization with percutaneous coronary intervention (PCI) reduces infarct size and improves outcomes in patients with ST-segment elevation myocardial infarction (STEMI). However, as ... -
Rationale for the ASSAIL-MI-trial: a randomised controlled trial designed to assess the effect of tocilizumab on myocardial salvage in patients with acute ST-elevation myocardial infarction (STEMI).
Anstensrud, Anne Kristine; Woxholt, Sindre; Sharma, Kapil Kishore; Broch, Kaspar; Bendz, Bjørn; Aakhus, Svend; Ueland, Thor; Amundsen, Brage H.; Damås, Jan Kristian; Hopp, Einar; Kleveland, Ola; STENSÆTH, KNUT HAAKON; Opdahl, Anders; Kløw, Nils-Einar; Seljeflot, Ingebjørg; Andersen, Geir Øystein; Wiseth, Rune; Aukrust, Pål; Gullestad, Lars (Journal article; Peer reviewed, 2019)Introduction Interleukin-6 (IL-6) may be involved in ischaemia-reperfusion injury and myocardial remodelling after myocardial infarction (MI). We have recently shown that IL-6 inhibition by tocilizumab attenuates systemic ... -
Return to work after hospitalization for sepsis: a nationwide, registry-based cohort study
Skei, Nina Vibeche; Moe, Karoline; Nilsen, Tom Ivar Lund; Aasdahl, Lene; Prescott, Hallie C.; Damås, Jan Kristian; Gustad, Lise Tuset (Peer reviewed; Journal article, 2023)Background Sepsis survivors commonly experience functional impairment, which may limit return to work. We investigated return to work (RTW) of patients hospitalized with sepsis and the associations with patient and ...