Browsing Institutt for nevromedisin og bevegelsesvitenskap by Subject "Neuroscience"
Now showing items 1-20 of 37
-
A characterization of the somatostatin expressing cell population in the lateral entorhinal cortex of the mouse
(Master thesis, 2016)The lateral entorhinal cortex is a part of the parahippocampal region, and has received attention for being involved in object and object characterization task, hence conveying nonspatial input to the hippocampal formation. ... -
A longitudinal study of amyloid beta 1-43 levels in cerebrospinal fluid from patients with amnestic mild cognitive impairment or early Alzheimer's disease
(Master thesis, 2015)Background: Alzheimer's disease (AD) is a severe neurodegenerative dis- ease and its prevalence is rising globally. Evidence suggests that the pathological lesion of AD in the brain starts 10-15 years before the onset of ... -
Amyloid β-immunoreactivity in cell populations of the hippocampal region in transgenic rat model of Alzheimer's disease
(Master thesis, 2015)Alzheimer’s disease (AD) is one of the most devastating neurodegenerative disorders and the most common cause of dementia in the elderly. Both amyloid β (Aβ) and tau pathology show a characteristic spatiotemporal progression ... -
Analysis of Spatial Memory Cell Types Projections in Entorhino-Entorhinal Circuitry Using Electronphysiological Neural Recordings Combined with Optogenetics Application
(Master thesis, 2015)Recent studies have revealed that all functional cell types in superficial layers of medial entorhinal cortex have projections to the hippocampus. Furthermore, hippocampal functions in connection with neural circuits in ... -
Attention outcome in the acute stage following uncomplicated and complicated mild traumatic brain injury
(Master thesis, 2015)This thesis examined the consequences mild Traumatic Brain Injury (TBI) has on neuropsychological measures of attention two weeks after injury, using the Cambridge Neuropsychological Test Automated Battery (CANTAB). Most ... -
Brain development after postnatal growth restriction and intermittent hyperoxia hypoxia in the neonatal rat : a longitudinal MRI study
(Master thesis, 2016)Children born prematurely are commonly exposed to perinatal events such as infections, apneutic attacks and poor lung performance. These conditions put the children at risk of a reduced oxygen uptake and tissue hypoxia. ... -
Characterising responses to mixtures of pheromones and plant odorants in the moth antennal lobe through clacium imaging
(Master thesis, 2016)Herbivorous insects as model organisms have been shown to be very useful in studies related to neuronal and molecular elements of the olfactory system, and for studying the mechanisms of olfactory coding. Naturally occurring ... -
Characterization of the Somatostatin cell population in the medial entorhinal cortex of the mouse
(Master thesis, 2016)The medial entorhinal cortex receives converging input from the hippocampal formation, the parahippocampal region and multiple neocortical and subcortical regions. Since the discovery of spatially modulated cells, the ... -
Cognitive control based decision-making correlates with c-Fos activation in the anterior cingulate cortex
(Master thesis, 2016)Flexibility in decision-making is usually linked to cognitive control. This is believed to be an essential element required for economically adaptive behaviors in an everchanging environment. With a flexible decision making ... -
Dendritic spine density in the default mode network : a postmortem morphometric pilot study of schizophrenia
(Master thesis, 2016)Neuroimaging studies have found decreased activity and functional connectivity within and between brain regions in subjects with schizophrenia. These findings correlate with a decline in dendritic spine density in the ... -
Developing long-term in vitro microculture for neuropathology modelling
(Master thesis, 2016)Background: The regenerative capacity of the adult mammalian central nervous system is limited, while neuronal responses to injury, including axonal and synaptic plasticity are highly complex and evolve in a spatiotemporal ... -
Developing real-time tracking software and setup for studying active avoidance conditioning in zebrafish
(Master thesis, 2016)The cognitive capabilities of fish have historically been underestimated and, in many respects, they are comparable to birds and mammals. Currently, an increasing number of behavioural neuroscience laboratories have started ... -
Development of smooth pursuit and predictive eye movements in full-term and preterm infants : an occlusion study
(Master thesis, 2015)When a moving object disappears behind an occluding surface, the prediction of its reappearance must be made across time and space and this not only requires a maintained representation of the existence but also the ... -
Enhanced lentiviral vectors : a comparison of enhancer driven expression of transgenes transferred by pronuclear injection or lentiviral vectors
(Master thesis, 2016)The brain is a vast network of different types of neurons. Interactions between these different types of neurons underlie the different kinds of neural computations the brain performs. How the different types of neurons ... -
Exploring differences in protein metabolites in cerebrospinal fluid from patients with Alzheimer's disease, frontotemporal dementia or amyotrophic lateral sclerosis : a pilot study
(Master thesis, 2016)Background: FTD is the second commonest presentation of early onset dementia after AD. While the clinical features, pathophysiology and genetics of FTD are heterogeneous, AD is a more homogenous disease. Despite the ... -
High-density EEG study of how looming information is processed in the infant brain
(Master thesis, 2015)Looming images indicate the rapid approach of objects and provide warning information about the impending impact. Prospective control when responding to a looming virtual object approaching on a direct collision course was ... -
Immunohistochemical and electrophysiological characterization of principal cells in layer II of the lateral entorhinal cortex
(Master thesis, 2015)The entorhinal cortex (EC) is a part of the medial temporal lobe of the brain, and is considered to be important for learning and memory. The EC can be divided into two subdivisions; the lateral EC (LEC) and the medial EC ... -
Immunohistochemical and morphological characterization of GABAergic cells in LEC
(Master thesis, 2015)The two subdivisions of the entorhinal cortex, the medial and the lateral entorhinal cortex have been implicated a crucial role in spatial cognition but appear to be functionally distinct. To understand the functional ... -
Interneurons in a two population grid cell network
(Master thesis, 2015)The hexagonal firing pattern of entorhinal grid cells could arise from a competitive mechanism mediated by interneurons. In this thesis, we asked if a two-population continuous attractor model, consistent with the proposed ...