• Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases. 

      de Jesus, Adriana Almeida; Hou, Yangfeng; Brooks, Stephen; Malle, Louise; Biancotto, Angelique; Huang, Yan; Calvo, Katherine R.; Marrero, Bernadette; Moir, Susan; Oler, Andrew J.; Deng, Zuoming; Sanchez, Gina A. Montealegre; Ahmed, Amina; Allenspach, Eric; Srabshahi, Bita; Behrens, Edward M.; Benseler, Susanne; Berzrodnik, Liliana; Bout-Tabaku, Sharon; Brescia, AnneMarie; Brown, Diane; Burnham, Jon M.; Caldirola, Maria Soledad; Carrasco, Ruy; Chan, Alice; Cimaz, Rolando; Dancey, Paul; Dare, Jason; DeGuzman, Marietta; Dimitriades, Victoria; Ferguson, Ian; Ferguson, Polly J.; Finn, Laura; Gattorno, Marco; Grom, Alexei; Hanson, Eric P.; Hashkes, Philip; Hedrich, Christian M.; Herzog, Ronit; Horneff, Gerd; Jerath, Rita; Kessler, Elizabeth; Kim, Hanna; Kingsbury, Daniel J.; Laxer, Ronald M; Lee, Pui Y.; Lee-Kirsch, Min Ae; Lewandowski, Laura; Li, Suzanne; Lilleby, Vibke; Mammadova, Vafa; Moorthy, Lakshmi N.; Nasrullayeva, Gulnara M.; O'Neill, Kathleen; Onel, Karen; Ozen, Seza; Pan, Nancy; Pillet, Pascal; Piotto, Daniela G. P.; Punaro, Marilynn G.; Reiff, Andreas; Reinhardt, Adam L.; Rider, Lisa G.; Rivas-Chacon, Rafael; Ronis, Tova; Rosen-Wolff, Angela; Roth, Johannes; Ruth, Natasha Mckerran; Rygg, Marite; Schmeling, Heinrike; Schulert, Grant; Scott, Christiaan; Seminario, Gisella; Schulman, Andrew; Sivaraman, Vidya; Son, Mary Beth; Stepanovskiy, Yuriy; Stringer, Elizabeth; Taber, Sara; Terreri, Maria Teresa; Tifft, Cynthia J; Torgerson, Troy R.; Tosi, Laura; Royen-Kerkhof, Annet Van; Muskardin, Theresa Wampler; Canna, Scott W.; Goldbach-Mansky, Raphaela (Peer reviewed; Journal article, 2020)
      BACKGROUND. Undifferentiated systemic autoinflammatory diseases (USAIDs) present diagnostic and therapeutic challenges. Chronic interferon (IFN) signaling and cytokine dysregulation may identify diseases with available ...
    • Distinct pain profiles in patients with chronic obstructive pulmonary disease 

      Bentsen, Signe Berit; Miaskowski, Christine; Cooper, Bruce A.; Christensen, Vivi Lycke; Henriksen, Anne Hildur; Holm, Are Martin; Rustøen, Tone (Journal article; Peer reviewed, 2018)
      Background: Few studies have examined changes in the pain experience of patients with COPD and predictors of pain in these patients. Objectives: The objectives of the study were to examine whether distinct groups of COPD ...
    • Distinguishing sleep from wake with a radar sensor: A contact-free real-time sleep monitor 

      Heglum, Hanne Siri Amdahl; Kallestad, Håvard; Vethe, Daniel; Langsrud, Knut; Sand, Trond; Engstrøm, Morten (Journal article; Peer reviewed, 2021)
      This work aimed to evaluate whether a radar sensor can distinguish sleep from wakefulness in real time. The sensor detects body movements without direct physical contact with the subject and can be embedded in the roof of ...
    • Distortion of complexity in oscillations of arterial blood pressure, due to aging 

      Orten, Erik Norvald (Master thesis, 2017)
      Age both influences and limits an individual’s capability to withstand adverse circulatory distress such as sepsis or cardiac events, and is by itself considered a major risk factor for hypertension. The aim of this study ...
    • Distress due to COVID-19 in women giving birth during the pandemic: A cross-sectional study from Norway 

      Reppen, Kristin (Master thesis, 2023)
      Introduksjon: SARS-CoV-2 (COVID-19) påvirket kvinner i fødselsomsorg over hele verden. Få studier omhandler hvordan pandemien påvirket kvinner i fødsel, og vi vet lite om hvordan smitteverntiltak påvirket kvinners angst, ...
    • Distribution and prevalence of musculoskeletal pain co-occurring with persistent low back pain: a systematic review 

      Øverås, Cecilie Krage; Johansson, Melker S; de Campos, Tarcisio F; Ferreira, Manuela L.; Natvig, Bård; Mork, Paul Jarle; Hartvigsen, Jan (Peer reviewed; Journal article, 2021)
      Background Co-occurring musculoskeletal pain is common among people with persistent low back pain (LBP) and associated with more negative consequences than LBP alone. The distribution and prevalence of musculoskeletal ...
    • Distribution and prevalence of musculoskeletal pain co-occurring with persistent low back pain: a systematic review 

      Johansson, Melker S; de Campos, Tarcisio F.; Ferreira, Manuela L.; Natvig, Bård; Mork, Paul Jarle; Hartvigsen, Jan (Peer reviewed; Journal article, 2021)
      Background Co-occurring musculoskeletal pain is common among people with persistent low back pain (LBP) and associated with more negative consequences than LBP alone. The distribution and prevalence of musculoskeletal ...
    • Disturbed body image and compulsive exercise in female eating disorder patients 

      Danielsen, Marit (Doctoral thesis at NTNU;2013: 123, Doctoral thesis, 2016)
      Norsk sammendrag Bakgrunn: Kroppsbildeforstyrrelser og tvangspreget trening er definert som sentrale symptomområder hos pasienter med spiseforstyrrelser. Forskning har knyttet begge områdene til hele sykdomsforløpet; ...
    • Disulfiram repurposing combined with nutritional copper supplement as add-on to chemotherapy in recurrent glioblastoma (DIRECT): Study protocol for a randomized controlled trial 

      Jakola, Asgeir S.; Werlenius, Katja; Mudaisi, Munila; Hylin, Sofia; Kinhult, Sara; bartek, Jiri Jr.; Salvesen, Øyvind; Carlsen, Sven Magnus; Strandeus, Michael; Lindskog, Magnus; Lofgren, David; Rydenhaug, Bertil; Carstam, Louise; Gulati, Sasha; Solheim, Ole; Bartek, Jiri; Solheim, Tora Skeidsvoll (Journal article; Peer reviewed, 2018)
      Background: Disulfiram (DSF) is a well-tolerated, inexpensive, generic drug that has been in use to treat alcoholism since the 1950s. There is now independent preclinical data that supports DSF as an anticancer agent, and ...
    • Diurnal rhythms in the human urine metabolome during sleep and total sleep deprivation 

      Giskeødegård, Guro F.; Davies, Sarah K; Revell, Victoria L; Keun, Hector C.; Skene, Debra J (Peer reviewed; Journal article, 2015)
      Understanding how metabolite levels change over the 24 hour day is of crucial importance for clinical and epidemiological studies. Additionally, the association between sleep deprivation and metabolic disorders such as ...
    • Divalent ligand-monovalent molecule binding 

      Janssen, Mathijs Adriaan; Stenmark, Harald; Carlson, Andreas (Peer reviewed; Journal article, 2021)
      Simultaneous binding of a divalent ligand to two identical monovalent molecules is a widespread phenomenon in biology and chemistry. Here, we describe how two such monovalent molecules B bind to a divalent ligand AA to ...
    • Divergent decennial trends in mental health according to age reveal poorer mental health for young people: Repeated cross-sectional population-based surveys from the HUNT Study, Norway 

      Krokstad, Steinar; Weiss, Daniel Albert; Krokstad, Morten Austheim; Rangul, Vegar; Kvaløy, Kirsti; Ingul, Jo Magne; Bjerkeset, Ottar; Twenge, Jean; Sund, Erik (Peer reviewed; Journal article, 2022)
      Objectives Public health trends are formed by political, economic, historical and cultural factors in society. The aim of this paper was to describe overall changes in mental health among adolescents and adults in a Norwegian ...
    • Divergent Regulation of Decidual Oxidative-Stress Response by NRF2 and KEAP1 in Preeclampsia with and without Fetal Growth Restriction 

      Mundal, Siv Boon; Rakner, Johanne Johnsen; Silva, Gabriela; Gierman, Lobke; Austdal, Marie; Basnet, Purusotam; Elschot, Mattijs; Bakke, Siril Skaret; Ostrop, Jenny; Thomsen, Liv Cecilie Vestrheim; Moses, Eric; Acharya, Ganesh; Bjørge, Line; Iversen, Ann-Charlotte (Peer reviewed; Journal article, 2022)
      Utero-placental development in pregnancy depends on direct maternal–fetal interaction in the uterine wall decidua. Abnormal uterine vascular remodeling preceding placental oxidative stress and placental dysfunction are ...
    • Diverse functions of DNA glycosylases processing oxidative base lesions in brain 

      Scheffler, Katja; Bjørås, Karine Øian; Bjørås, Magnar (Peer reviewed; Journal article, 2019)
      Endogenous and exogenous oxidative agents continuously damage genomic DNA, with the brain being particularly vulnerable. Thus, preserving genomic integrity is key for brain health and neuronal function. Accumulation of DNA ...
    • Diversity and function of motile ciliated cell types within ependymal lineages of the zebrafish brain 

      Dgama, Percival Paul Menino; Qiu, Tao; Cosacak, Mehmet Ilyas; Rayamajhi, Dheeraj; Konac, Ahsen; Hansen, Jan Niklas; Ringers, Christa; Acuna Hinrichsen, Francisca Daniela; Hui, Subhra; Olstad, Emilie Willoch; Chong, Yan Ling; Lim, Charlton Kang An; Gupta, Astha; Ng, Chee Peng; Nilges, Benedikt S.; Kashikar, Nachiket; Wachten, Dagmar; Liebl, David; Kikuchi, Kazu; Kizil, Caghan; Yaksi, Emre; Roy, Sudipto; Jurisch-Yaksi, Nathalie (Peer reviewed; Journal article, 2021)
      Motile cilia defects impair cerebrospinal fluid (CSF) flow and can cause brain and spine disorders. The development of ciliated cells, their impact on CSF flow, and their function in brain and axial morphogenesis are not ...
    • Diversity in changes of HRQoL over a one-year period after radiotherapy in Norwegian breast cancer survivors – results of cluster analyses 

      Lazarewicz, Magdalena Anna; Wlodarczyk, Dorota; Lundgren, Steinar; Reidunsdatter, Randi Johansen (Journal article; Peer reviewed, 2019)
      Purpose The diversity in long-term changes in health-related quality of life (HRQoL) among breast cancer (BC) survivors is poorly understood. The aim of this study was to identify clusters of trajectories (subgroups of ...
    • Diversity of vaginal microbiota increases by the time of labor onset 

      Avershina, Ekaterina; Slangsvold, Silje; Simpson, Melanie Rae; Storrø, Ola; Johnsen, Roar; Øien, Torbjørn; Rudi, Knut (Journal article; Peer reviewed, 2017)
      Vaginal microbiota is an important early source of bacterial colonization for newborns. However, only a few small studies have investigated the composition of vaginal microbiota during labor. In this work, we analyzed ...
    • Diving In Extreme Environments:: The Scientific Diving Experience 

      Lang, Michael A. (Doktoravhandlinger ved NTNU, 1503-8181; 2012:248, Doctoral thesis, 2012)
      The scope of extreme-environment diving defined within this work encompasses diving modes outside of the generally accepted no-decompression, open-circuit, compressed-air diving limits on selfcontained underwater breathing ...
    • Divorce and adolescent academic achievement: Heterogeneity in the associations by parental education 

      Nilsen, Sondre Aasen; Breivik, Kyrre; Wold, Bente; Askeland, Kristin Gärtner; Sivertsen, Børge; Hysing, Mari; Bøe, Tormod (Peer reviewed; Journal article, 2020)
      Background The link between parental divorce and adolescents’ academic achievement may depend on parental educational levels. However, findings have been inconsistent regarding whether the negative associations between ...
    • Divulging a Pleiotropic Role of Succinate Receptor SUCNR1 in Renal Cell Carcinoma Microenvironment 

      Najm, Rania; Hachim, Mahmood Yaseen; Kandasamy, Richard Kumaran (Peer reviewed; Journal article, 2022)
      The succinate receptor, SUCNR1, has been attributed to tumor progression, metastasis, and immune response modulation upon its activation via the oncometabolite succinate. Nonetheless, little is known about the prognostic ...