• Molecular alterations in oral cancer using high-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue 

      Subbannayya, Yashwanth; Pinto, Sneha M. (Journal article, 2021)
      Loss of cell differentiation is a hallmark for the progression of oral squamous cell carcinoma (OSCC). Archival Formalin-Fixed Paraffin-Embedded (FFPE) tissues constitute a valuable resource for studying the differentiation ...
    • Molecular and functional characterization of breast cancer through a combination of MR imaging, transcriptomics and metabolomics 

      Moestue, Siver Andreas (Doktoravhandlinger ved NTNU, 1503-8181; 2012:14, Doctoral thesis, 2012)
      Breast cancer is the most frequent cancer among women in Norway. The outcome of this disease is heterogeneous. Some patients have slowly growing tumors which stay confined within the mammary gland, whereas others have ...
    • Molecular basis of mycobacterial survival in macrophages 

      Awuh, Jane Atesoh; Flo, Trude Helen (Journal article; Peer reviewed, 2017)
      Macrophages play an essential role in the immune system by ingesting and degrading invading pathogens, initiating an inflammatory response and instructing adaptive immune cells, and resolving inflammation to restore ...
    • Molecular biomarkers of prostate cancer 

      Hansen, Ailin Falkmo (Doctoral theses at NTNU;2017:337, Doctoral thesis, 2017)
    • The molecular characteristics of high-grade gastroenteropancreatic neuroendocrine neoplasms 

      Venizelos, Andreas; Elvebakken, Hege; Perren, Aurel; Nikolaienko, Oleksii; Deng, Wei; Lothe, Inger Marie Bowitz; Couvelard, Anne; Hjortland, Geir Olav; Sundlöv, Anna; Svensson, Johanna; Garresori, Herish; Kersten, Christian; Hofsli, Eva; Detlefsen, Sönke; Krogh, Merete; Sørbye, Halfdan; Knappskog, Stian (Peer reviewed; Journal article, 2021)
      High-grade (HG) gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) are rare but have a very poor prognosis and represent a severely understudied class of tumours. Molecular data for HG GEP-NEN are limited, and ...
    • Molecular characterization of dexamethasone-induced protein-DEXI, encoded by a multiple sclerosis susceptibility gene 

      Emini, Nora (Master thesis, 2024)
      Multippel sklerose er en nevrologisk autoimmune sykdom som påvirker det sentrale nervesystemet ved demyelinisering og tap av nevroner. Den underliggende årsaken er ukjent, men det er antatt å være et samspill mellom genetikk ...
    • Molecular Characterization of the Extracellular Matrix Protein TINAGL1 in Breast Cancer 

      Sarlak, Saharnaz (Master thesis, 2014)
      Previous work in this group using Mass Spectrometry (MS) analysis of extracellular matrix (ECM) from breast tumor samples at different tumor stages, had reported that TINAGL1 is highly expressed during breast carcinogenesis ...
    • Molecular Epidemiology and Evolutionary Trajectory of Emerging Echovirus 30, Europe. 

      Benschop, Kimberley; Broberg, Eeva; Hodcroft, E; Schmitz, D; Albert, Jan; Baicus, A; Bailly, Jean-Luc; Baldvinsdottir, Gudrun; Berginc, N; Blomqvist, S; Böttcher, S; Brytting, M; Bujaki, Erika; Cabrerizo, Maria; Celma, Cristina; Cinek, Ondrej; Claas, Eric CJ; Cremer, Jeroen; Dean, Jonathan; Dembinski, Jennifer Lynn; Demchyshyna, Iryna; Diedrich, Sabine; Dudman, Susanne Gjeruldsen; Dunning, Jake; Dyrdak, Robert; Emmanouil, Mary; Farkas, Agnes; De Gascun, Cillian; Fournier, Guillaume; Georgieva, Irina; Gonzalez-Sanz, Ruben; van Hooydonk-Elving, Jolanda; Jääskeläinen, A. J.; Jancauskaite, Ruta; Keeren, Kathrin; Fischer, Thea Kølsen; Krokstad, Sidsel; Nikolaeva–Glomb, Lubomira; Novakova, Ludmila; Midgley, SE; Mirand, Audrey; Molenkamp, Richard; Morley, Ursula; Mossong, Joël; Muralyte, Svajune; Murk, Jean-Luc; Nguyen, Trung; Nordbø, Svein Arne; Österback, Riikka; Pas, Suzan; Pellegrinelli, Laura; Pogka, Vassiliki; Prochazka, Birgit; Rainetova, Petra; Van Ranst, Marc; Roorda, Lieuwe; Schuffenecker, Isabelle; Schuurman, Rob; Stoyanova, Asya; Templeton, Kate E.; Verweij, Jaco J.; Voulgari-Kokota, Androniki; Vuorinen, Tytti; Wollants, Elke; Wolthers, Katja; Zakikhany, Katherina; Neher, Richard; Harvala, Heli; Simmonds, Peter (Journal article; Peer reviewed, 2021)
      In 2018, an upsurge in echovirus 30 (E30) infections was reported in Europe. We conducted a large-scale epidemiologic and evolutionary study of 1,329 E30 strains collected in 22 countries in Europe during 2016–2018. Most ...
    • Molecular Features of Subtype-Specific Progression from Ductal Carcinoma In Situ to Invasive Breast Cancer 

      Lesurf, Robert; Aure, Miriam Ragle; Mørk, Hanne Håberg; Vitelli, Valeria; Lundgren, Steinar; Børresen-Dale, Anne-Lise; Kristensen, Vessela N.; Wärnberg, Fredrik; Hallett, Michael; Sørlie, Therese (Peer reviewed; Journal article, 2016)
      Breast cancer consists of at least five main molecular “intrinsic” subtypes that are reflected in both pre-invasive and invasive disease. Although previous studies have suggested that many of the molecular features of ...
    • Molecular mechanisms involved in TNF - and gastrin-mediated gene regulation 

      Thommesen, Liv (Dissertations at the Faculty of Medicine, 0805-7680; 189, Doctoral thesis, 2001)
      Cells in a multicellular organism depend on extensive communication with each other. Eukaryotic cells have developed elaborate signal transduction systems by which externally provided information (hormones, cytokines, ...
    • Molecular Mechanisms of NLRP3 Inflammasome Activation by Crystalline Material 

      Samstad, Eivind Ottersen (Doctoral thesis at NTNU;2015:18, Doctoral thesis, 2015)
    • Molecular mechanisms of the proliferative response to the hormone gastrin 

      Steigedal, Tonje Strømmen (Doktoravhandlinger ved NTNU, 1503-8181; 2009:256, Doctoral thesis, 2009)
        Molekylære mekanismer til den proliferative responsen til hormonet gastrin Menneskekroppen består av mange ulike celletyper som alle inneholder det samme arvemateriealet (DNA) som koder for mellom 20.000 og 30.000 ...
    • Molecular Mechanisms of Vascular Health: Insights From Vascular Aging and Calcification 

      Sutton, Nadia R.; Malhotra, Rajeev; Hilaire, Cynthia S.; Aikawa, Elena; Blumenthal, Roger S.; Gackenbach, Grace; Goyal, Parag; Johnson, Adam; Nigwekar, Sagar U.; Shanahan, Catherine M.; Towler, Dwight A.; Wolford, Brooke Nichole; Chen, Yabing (Peer reviewed; Journal article, 2023)
      Cardiovascular disease is the most common cause of death worldwide, especially beyond the age of 65 years, with the vast majority of morbidity and mortality due to myocardial infarction and stroke. Vascular pathology stems ...
    • Molecular Methods for Typing of Streptococcus agalactiae with Special Emphasis on the Development and Validation of a Multi-Locus Variable Number of Tandem Repeats Assay (MLVA) 

      Radtke, Andreas (Doktoravhandlinger ved NTNU, 1503-8181; 2012:28, Doctoral thesis, 2012)
      Molekylære metoder for typing av Streptococcus agalactiae med særlig vektlegging av utvikling og validering av et multi-locus variable number of tandem repeats assay (MLVA) Sammendraget: Streptococcus agalactiae eller ...
    • Molecular Resistance Fingerprint of Pemetrexed and Platinum in a Long-Term Survivor of Mesothelioma 

      Røe, Oluf Dimitri; Szulkin, Adam; Anderssen, Endre; Flatberg, Arnar; Sandeck, Helmut; Amundsen, Tore; Erlandsen, Sten Even; Dobra, Katalin; Sundstrøm, Stein Harald (Journal article; Peer reviewed, 2012)
    • Molecular Subtypes and Survival in a Historic Cohort of Women with Breast Cancer 

      Engstrøm, Monica Jernberg (Doctoral thesis at NTNU;2015:56, Doctoral thesis, 2015)
      Molekylære subtyper og overlevelse i en historisk kohort av kvinner med brystkreft Målsetningen med studiene bak denne avhandlingen var å bidra til bedre klassifisering av brystkreft i prognostiske grupper. Arbeidet er ...
    • Molecular subtypes of breast cancer: incidence and prognosis 

      Valla, Marit (Doctoral theses at NTNU;2017:276, Doctoral thesis, 2017)
      Forekomsten av brystkreft har over flere tiår økt i den vestlige verden, og i Norge har det vært en dobling av insidensen siden Kreftregisteret startet sin overvåkning av antall krefttilfeller i Norge i 1952. I Norge har ...
    • Molecular Subtypes of Breast Cancer: Long-term Incidence Trends and Prognostic Differences 

      Valla, Marit; Vatten, Lars Johan; Engstrøm, Monica J; Haugen, Olav Anton; Akslen, Lars A.; Bjørngaard, Johan Håkon; Hagen, Anne Irene; Ytterhus, Borgny; Bofin, Anna M.; Opdahl, Signe (Journal article; Peer reviewed, 2016)
      Background: Secular trends in incidence and prognosis of molecular breast cancer subtypes are poorly described. We studied long-term trends in a population of Norwegian women born 1886–1977. Methods: A total of 52,949 ...
    • Molecular subtypes, histopathological grade and survival in a historic cohort of breast cancer patients 

      Engstrøm, Monica J; Opdahl, Signe; Hagen, Anne Irene; Romundstad, Pål Richard; Akslen, Lars A.; Haugen, Olav A.; Vatten, Lars Johan; Bofin, Anna M. (Peer reviewed; Journal article, 2013)
      Molecular subtyping of breast cancer may provide additional prognostic information regarding patient outcome. However, its clinical significance remains to be established. In this study, the main aims were to discover ...
    • Molecular tools and model systems for studying inflammasome activation 

      Kim, Haelin (Master thesis, 2019)
      Upon cellular stress or invasion by pathogens such as Mycobacterium tuberculosis (Mtb), inflammasomes are activated as an innate immune response, an important host-defense mechanism to resist pathogens. Activation of NLRP3 ...