Browsing Institutt for teknisk kybernetikk by Author "Carlsen, Sven Magnus"

Now showing items 1-11 of 11

    • A Review of the Current Challenges Associated with the Development of an Artificial Pancreas by a Double Subcutaneous Approach 

      Christiansen, Sverre; Fougner, Anders Lyngvi; Stavdahl, Øyvind; Kölle, Konstanze; Ellingsen, Reinold; Carlsen, Sven Magnus (Journal article; Peer reviewed, 2017)
      Introduction Patients with diabetes type 1 (DM1) struggle daily to achieve good glucose control. The last decade has seen a rush of research groups working towards an artificial pancreas (AP) through the application of a ...

    • The Artificial Pancreas: Two Alternative Approaches to Achieve a Fully Closed Loop System with Optimal Glucose Control 

      Åm, Marte Kierulf; Teigen, Ingrid Anna; Riaz, Misbah; Fougner, Anders Lyngvi; Christiansen, Sverre Christian; Carlsen, Sven Magnus (Peer reviewed; Journal article, 2023)
      Introduction Diabetes mellitus type 1 is a chronic disease that implies mandatory external insulin delivery. The patients must monitor their blood glucose levels and administer appropriate insulin boluses to keep their ...

    • Differences Between Flash Glucose Monitor and Fingerprick Measurements 

      Staal, Odd Martin; Hansen, Heidi Marie Umbach; Christiansen, Sverre; Fougner, Anders Lyngvi; Carlsen, Sven Magnus; Stavdahl, Øyvind (Journal article; Peer reviewed, 2018)
      Freestyle Libre (FL) is a factory calibrated Flash Glucose Monitor (FGM). We investigated Mean Absolute Relative Difference (MARD) between Self Monitoring of Blood Glucose (SMBG) and FL measurements in the first day of ...

    • Effect of sensor location on continuous intraperitoneal glucose sensing in an animal model 

      Åm, Marte Kierulf; Kölle, Konstanze; Fougner, Anders Lyngvi; Dirnena-Fusini, Ilze; Bösch, Patrick Christian; Ellingsen, Reinold; Hjelme, Dag Roar; Stavdahl, Øyvind; Carlsen, Sven Magnus; Christiansen, Sverre (Journal article; Peer reviewed, 2018)
      In diabetes research, the development of the artificial pancreas has been a major topic since continuous glucose monitoring became available in the early 2000’s. A prerequisite for an artificial pancreas is fast and reliable ...

    • Feasibility of early meal detection based on abdominal sound. 

      Kölle, Konstanze; Fougner, Anders Lyngvi; Ellingsen, Reinold; Carlsen, Sven Magnus; Stavdahl, Øyvind (Journal article; Peer reviewed, 2019)
      Background In classical approaches for an artificial pancreas, continuous glucose monitoring (CGM) is the only measured variable used for insulin dosing and additional control functions. The CGM values are subject to time ...

    • Intraperitoneal and subcutaneous glucagon delivery in anaesthetized pigs: effects on circulating glucagon and glucose levels 

      Åm, Marte Kierulf; Dirnena-Fusini, Ilze; Fougner, Anders Lyngvi; Carlsen, Sven Magnus; Christiansen, Sverre (Journal article; Peer reviewed, 2020)
      Glucagon is a pancreatic hormone and increases the blood glucose levels. It may be incorporated in a dual hormone artificial pancreas, a device to automatically and continuously control blood glucose levels of individuals ...

    • Intraperitoneal insulin administration in pigs: Effect on circulating insulin and glucose levels 

      Dirnena-Fusini, Ilze; Åm, Marte Kierulf; Fougner, Anders Lyngvi; Carlsen, Sven Magnus; Christiansen, Sverre Christian (Peer reviewed; Journal article, 2021)
      Introduction The effect of intraperitoneal insulin infusion has limited evidence in the literature. Therefore, the aim of the study was to investigate the pharmacokinetics and pharmacodynamics of different intraperitoneal ...

    • Intraperitoneal, subcutaneous and intravenous glucagon delivery and subsequent glucose response in rats: A randomized controlled crossover trial 

      Dirnena-Fusini, Ilze; Åm, Marte Kierulf; Fougner, Anders Lyngvi; Carlsen, Sven Magnus; Christiansen, Sverre (Journal article; Peer reviewed, 2018)
      Objective Hypoglycemia is a frequent and potentially dangerous event among patients with diabetes mellitus type 1. Subcutaneous glucagon is an emergency treatment to counteract severe hypoglycemia. The effect of intraperitoneal ...

    • Risk Analysis for the Design of a Safe Artificial Pancreas Control System 

      Kölle, Konstanze; Fougner, Anders Lyngvi; Lundteigen, Mary Ann; Carlsen, Sven Magnus; Ellingsen, Reinold; Stavdahl, Øyvind (Journal article; Peer reviewed, 2018)
      Closed-loop glucose control has the potential to improve the glycemic control in patients with diabetes mellitus type 1. Such an artificial pancreas (AP) should keep the user safe despite all disturbances and faults. The ...

    • The Artificial Pancreas: A Dynamic Challenge 

      Stavdahl, Øyvind; Fougner, Anders Lyngvi; Kölle, Konstanze; Christiansen, Sverre Christian; Ellingsen, Reinold; Carlsen, Sven Magnus (Journal article; Peer reviewed, 2016)
      In patients with diabetes mellitus type 1, the pancreatic insulin production ceases, causing raise in blood glucose level (BGL) and potentially severe long-term complications. The “holy grail” of diabetes treatment is the ...

    • Why intraperitoneal glucose sensing is sometimes surprisingly rapid and sometimes slow: A hypothesis 

      Åm, Marte Kierulf; Fougner, Anders Lyngvi; Ellingsen, Reinold; Hjelme, Dag Roar; Bösch, Patrick Christian; Stavdahl, Øyvind; Carlsen, Sven Magnus; Christiansen, Sverre (Journal article; Peer reviewed, 2019)
      The artificial pancreas requires fast and reliable glucose measurements. The peritoneal space has shown promising results, and in one of our studies we detected glucose changes in the peritoneal space already at the same ...