Blar i Institutt for kjemi på tittel
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Synthesis of phenothiazine derivatives as small molecular acceptors for organic photovoltaics
(Master thesis, 2019)For å oppnå de Forente Nasjoners 17 bærekraftsmål som ble vedtatt i 2015 må en økning i bærekraftig energiproduksjon til. Veksten i solenergimarkedet er hurtig, og utviklingen av alternativer til silisiumbaserte solceller ... -
Synthesis of Phenothiazine Dyes Containing Thiophene and Diketopyrrolopyrrole pi-Bridge for Use in DSSCs
(Master thesis, 2019)Fargestoff-solceller er nye og voksende fotovoltaiske teknologier som gjør at solceller kan være halvtransparente, fleksible og av justerbar farge. Disse solcellene har utkonkurrert de fleste andre etablerte fotovoltaiske ... -
Synthesis of polynucleotide analogs containing a polyvinyl alcohol backbone
(Journal article; Peer reviewed, 2008)Water soluble homo-base polynucleotide analogues were synthesized in which polyvinyl alcohol and partially phosphonated polyvinyl alcohol constituted the backbones, onto which were grafted uracil or adenine via 1,3-dioxane ... -
Synthesis of Pyrrolopyrimidines as CSF-1R Kinase Inhibitors
(Master thesis, 2016) -
Synthesis of pyrrolopyrimidines for CSF-1R inhibition
(Master thesis, 2017) -
Synthesis of Pyrrolopyrimidines for Investigation of JAK2 Inhibition
(Master thesis, 2015)A series of 7H-pyrrolo- and thieno[2,3-d]pyrimidine based compounds have been synthesized and tested for Janus kinase 2 (JAK2) inhibition, as part of a fragment-based approach to obtaining information on structure-activity ... -
Synthesis of Selectively Fully Protected Glucose Derivatives via a Furanose-to-Pyranose Rearrangement Method
(Master thesis, 2018)Towards the total synthesis of a natural anti-inflammatory compound present in the plant Sclerochloa dura, three full protection strategies were developed for selectively full protected glucose derivatives, available for ... -
Synthesis of Silica Aerogels with Single-Site Iron for Heterogeneous Catalysis
(Master thesis, 2019)Jern ble inkorporert i silika aerogeler laget med "waterglass" silika-forløper. Co-forløper (CP) syntesemetoden ble brukt i kombinasjon med en mer økonomisk tørking ved lavere temperatur og trykk (APD). En ny metode med ... -
Synthesis of Small 1,2,3-Triazoles for Antimicrobial Evaluation
(Master thesis, 2018)Antibiotic resistance is an increasing problem globally. Overuse exposes bacteria to different kinds of antibiotics, to which they in time become resistant to. It is therefore important to develop novel antimicrobial ... -
Synthesis of Small Cationic Amphiphiles for Antimicrobial Screening - Transition Metal Catalysed, Microwave-Mediated Indane Synthesis, and Subsequent Functionalisation
(Master thesis, 2017)Infectious diseases are a leading cause of death worldwide and account for more than 13 million deaths annually.[1] A growing ratio of these casualties can be attributed to antimicrobial resistance (AMR). In order to combat ... -
Synthesis of Small Cationic Amphiphiles for Antimicrobial Screening - Transition Metal Catalyzed Benzene Synthesis and Subsequent Functionalization
(Master thesis, 2016)The goal of this project has been to synthesize small cationic amphiphiles with bulky aromatic substituents on a benzene scaffold, for antimicrobial screening. The aromatic and cationic substituents were chosen based on ... -
Synthesis of Small Cationic Amphiphiles for Antimicrobial Screening - Transition Metal Catalyzed Pyridine Synthesis and Subsequent Functionalization
(Master thesis, 2016)The objective of the present thesis has been the synthesis of small cationic peptidomimetics based on a pharmacophore model devloped by Strøm et al. The peptedomimetics were synthesized by functionalization of substituted ... -
Synthesis of stable isotope labelled cathinone derivatives as internal standards for forensic and pharmaceutical analysis.
(Master thesis, 2016)The synthetic work presented in this thesis has focused on identifying efficient routes towards stable isotope labelled cathinone derivatives. These compounds will act as internal standards for forensic and pharmaceutical ... -
Synthesis of steroid analogs as potential CDK8 inhibitors using (S)-hydroxyalkyl azide in a stereoselective ring expansion
(Master thesis, 2021)CDK8 har en viktig rolle i regulering av celletranskripsjon gjennom enzymets tilknytning til mediatorkomplekset eller ved fosforylering av transkripsjonsfaktorer. CDK8-mediert aktivering av onkogener har vist seg å være ... -
Synthesis of Thieno[2,3-d]pyrimidine-Based EGFR-TK Inhibitors with Improved Solubility and Metabolic Stability
(Master thesis, 2015)The objective of this master s thesis was to synthesize EGFR tyrosine kinase inhibitors with enhanced aqueous solubility, metabolic stability and potency compared with commercially available inhibitors. Improving these ... -
Synthesis of Thymidylate Kinase Inhibitor Precursors
(Master thesis, 2019)Multimedikamentresistente bakterier er en av de største helseutfordringene verden står oven- for i dag, noe som gjør forskning og utvikling av ny antibiotika viktigere enn noen sinne. Hemming av et av nøkkelenzymene i ... -
Synthesis studies towards potential therapeutic agents against multiple myeloma (blood cancer)
(Master thesis, 2009) -
Synthesis, Characterization and Drug Loading of Multiresponsive p[NIPAm-co-PEGMA] (core)/p[NIPAm-co-AAc] (Shell) Nanogels with Monodisperse Size Distributions
(Journal article; Peer reviewed, 2018)We report the synthesis and properties of temperature- and pH-responsive p([NIPAm-co-PEGMA] (core)/[NIPAm-co-AAc] (shell)) nanogels with narrow size distributions, tunable sizes and increased drug loading efficiencies. The ... -
Synthesis, crystal structure and biological evaluation of N,N’-disubstituted guanidines
(Master thesis, 2024)Som del av et større forskningsprosjekt, var et av hovedmålene for denne masteroppgaven å syntetisere nye analoger av et «hit» stoff, med mål om å inhibere DNA glykosylasen NEIL2. Med bakgrunn i dette ble 17 N,N’-disubstituerte ...