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Epidemiology of gastro-oesophageal reflux A prospective population-based cohort study: The HUNT study
(Doktoravhandlinger ved NTNU, 1503-8181; 2014:69, Doctoral thesis, 2014)Introduction Heartburn and acid regurgitation are the characteristic gastro-oesophageal reflux symptoms (GORS). GORS are associated with reduced quality of life and increased risk of oesophageal adenocarcinoma. GORS are ... -
The Epidemiology of Insomnia and Sleep Duration Across Mental and Physical Health: The SHoT Study
(Peer reviewed; Journal article, 2021)Objective: Numerous epidemiological studies have been conducted to examine the prevalence and comorbidities of insomnia and document sleep duration, but a common limitation in many studies is the lack of use of agreed-upon ... -
Epidemiology of Opioid Drug Use in Patients with Chronic Non-Malignant Pain in Norway
(Doctoral thesis, 2015)increase in the opioid dose occurred in new users and previous low-dose opioid users, while stable or decreasing doses were more common in patients already receiving high doses of opioids. Eighty percent of patients who ... -
Epidemiology of paediatric trauma in Norway: a single-trauma centre observational study
(Journal article; Peer reviewed, 2019)BACKGROUND: Trauma is a major cause of mortality and morbidity in children globally. The burden of injury shows substantial geographical differences, with a significant mortality reduction in children in Norway during the ... -
Epidemiology of physical trauma at Dhulikhel hospital in Nepal - a 10 week survey
(Master thesis, 2013)Background: Dhulikhel Hospital (DH) is a Nepalese community hospital serving approximately 1 million people in the district of Kavre and its neighbouring areas. DH also provides services to outreach centres all over Nepal. ... -
Epidemiology of road traffic accidents in Lusaka, Zambia : trends, risk factors and countermeasures
(Master thesis, 2014)Road traffic accidents are major causes of morbidity and mortality. It is projected that by 2020 they will be 3rd leading cause of global disease burden. Less developed countries like Zambia account for about 85% of the ... -
Epidermal Gland Inspired Self-Repairing Slippery Lubricant-Infused Porous Coatings with Durable Low Ice Adhesion
(Journal article; Peer reviewed, 2019)The limited durability of slippery lubricant-infused porous surfaces (SLIPS) restricts their practical applications. Inspired by the epidermal glands of skins, we developed a facile approach to durable SLIPS with gland-like ... -
Epidurals during normal labour and birth — Midwives’ attitudes and experiences
(Peer reviewed; Journal article, 2020)Background Midwives have their own beliefs and values regarding pain during childbirth. Their preferences concerning labour pain management may influence women’s choices. Aim To gain a deeper understanding of midwives’ ... -
EpiFactors 2022: expansion and enhancement of a curated database of human epigenetic factors and complexes
(Journal article; Peer reviewed, 2023) -
EpiFactors: A comprehensive database of human epigenetic factors and complexes
(Peer reviewed; Journal article, 2015)Epigenetics refers to stable and long-term alterations of cellular traits that are not caused by changes in the DNA sequence per se . Rather, covalent modifications of DNA and histones affect gene expression and genome ... -
Epigenetic changes in human bronchial epithelial cells after in vitro transformation with chemical carcinogens - Analysis of cell migration and DNA methylation in FOXA genes
(Master thesis, 2013)Lung cancer is the leading cause of cancer related deaths worldwide. Cancer is caused by an accumulation of genetic and epigenetic changes that leads to alterations in gene activity and phenotype. There is emerging evidence ... -
Epigenetic changes in human bronchial epithelial cells after in vitro transformation with chemical carcinogens: Analysis of cell migration and DNA methylation in FOXA genes
(Master thesis, 2013)Lung cancer is the leading cause of cancer related deaths worldwide. Cancer is caused by an accumulation of genetic and epigenetic changes that leads to alterations in gene activity and phenotype. There is emerging evidence ... -
Epigenetic control of the intestinal epithelium A role for lysine-specific demethylase 1A during homeostasis and disease
(Doctoral theses at NTNU;2021:151, Doctoral thesis, 2021) -
Epigenetic mapping of the somatotropic axis in Nile tilapia reveals differential DNA hydroxymethylation marks associated with growth
(Peer reviewed; Journal article, 2021)In vertebrates, the somatotropic axis comprising the pituitary gland, liver and muscle plays a major role in myogenesis. Its output in terms of muscle growth is highly affected by nutritional and environmental cues, and ... -
Epigenetic mechanisms of lung carcinogenesis involve differentially methylated CpG sites beyond those associated with smoking
(Peer reviewed; Journal article, 2022)Smoking-related epigenetic changes have been linked to lung cancer, but the contribution of epigenetic alterations unrelated to smoking remains unclear. We sought for a sparse set of CpG sites predicting lung cancer and ... -
Epigenetic modulation of stem cells in neurodevelopment: The role of methylation and acetylation
(Journal article; Peer reviewed, 2017)The coordinated development of the nervous system requires fidelity in the expression of specific genes determining the different neural cell phenotypes. Stem cell fate decisions during neurodevelopment are strictly ... -
Epigenetics in the primary and secondary prevention of cardiovascular disease: influence of exercise and nutrition
(Peer reviewed; Journal article, 2022)Increasing evidence links changes in epigenetic systems, such as DNA methylation, histone modification, and non-coding RNA expression, to the occurrence of cardiovascular disease (CVD). These epigenetic modifications can ... -
Epigenetics mechanisms in toxicity and carcinogenicity of diesel exhaust particles - Particles induced variations in gene and microRNA expression in human bronchial epithelial cells
(Master thesis, 2015)Lung cancer is the leading cause of cancer related deaths worldwide. Several lines of evidence are confirming that air pollution significantly increase the risk of lung cancer. Exhaust from diesel engines is a component ... -
Epigenetiske effekter av fysisk aktivitet
(Bachelor thesis, 2019)Dette litteraturstudiet inkluderte åtte studier og hadde som hensikt å undersøke om trening har epigenetiske effekter. DNA- metylering var den epigenetiske mekanismen som ble undersøkt. For å finne originallitteratur ble ... -
Epigenetiske forandringer i in vitro transformerte humane bronkieepitelcellelinjer: Vekstpotensiale og DNA-metylering i FOXA-gener
(Master thesis, 2013)Lungekreft har vært den mest utbredte formen for kreft i verden i flere tiår og det er behov for økt kunnskap om cellulære mekanismer som ligger til grunn for sykdommen. Tradisjonelt har kreft blitt sett på som en genetisk ...