dc.contributor.author | Bauer, Michael | |
dc.contributor.author | Glenn, Tasha | |
dc.contributor.author | Achtyes, Eric D. | |
dc.contributor.author | Alda, Martin | |
dc.contributor.author | Agaoglu, Esen | |
dc.contributor.author | Altınbaş, Kürsat | |
dc.contributor.author | Andreassen, Ole | |
dc.contributor.author | Angelopoulos, Elias | |
dc.contributor.author | Ardau, Raffaella | |
dc.contributor.author | Aydin, Memduha | |
dc.contributor.author | Ayhan, Yavuz | |
dc.contributor.author | Baethge, Christopher | |
dc.contributor.author | Bauer, Rita | |
dc.contributor.author | Baune, Bernhard T. | |
dc.contributor.author | Balaban, Ceylan | |
dc.contributor.author | Becerra-Palars, Claudia | |
dc.contributor.author | Behere, Aniruddh P. | |
dc.contributor.author | Behere, Prakash B. | |
dc.contributor.author | Belete, Habte | |
dc.contributor.author | Belete, Tilahun | |
dc.contributor.author | Belizario, Gabriel Okawa | |
dc.contributor.author | Bellivier, Frank | |
dc.contributor.author | Belmaker, Robert H. | |
dc.contributor.author | Benedetti, Francesco | |
dc.contributor.author | Berk, Michael | |
dc.contributor.author | Bersudsky, Yuly | |
dc.contributor.author | Bicakci, Şule | |
dc.contributor.author | Birabwa-Oketcho, Harriet | |
dc.contributor.author | Bjella, Thomas | |
dc.contributor.author | Brady, Conan | |
dc.contributor.author | Cabrera, Jorge | |
dc.contributor.author | Cappucciati, Marco | |
dc.contributor.author | Castro, Angela Marianne Paredes | |
dc.contributor.author | Chen, Wei-Ling | |
dc.contributor.author | Cheung, Eric Y. W. | |
dc.contributor.author | Chiesa, Silvia | |
dc.contributor.author | Crowe, Marie | |
dc.contributor.author | Cuomo, Alessandro | |
dc.contributor.author | Dallaspezia, Sara | |
dc.contributor.author | Del Zompo, Maria | |
dc.contributor.author | Desai, Pratikkumar | |
dc.contributor.author | Dodd, Seetal | |
dc.contributor.author | Etain, Bruno | |
dc.contributor.author | Fagiolini, Andrea | |
dc.contributor.author | Fellendorf, Frederike T. | |
dc.contributor.author | Ferensztajn-Rochowiak, Ewa | |
dc.contributor.author | Fiedorowicz, Jess G. | |
dc.contributor.author | Fountoulakis, Kostas N. | |
dc.contributor.author | Frye, Mark A. | |
dc.contributor.author | Geoffroy, Pierre A. | |
dc.contributor.author | Gitlin, Michael J. | |
dc.contributor.author | Gonzalez-Pinto, Ana | |
dc.contributor.author | Gottlieb, John F. | |
dc.contributor.author | Grof, Paul | |
dc.contributor.author | Haarman, Bartholomeus C. M. | |
dc.contributor.author | Harima, Hirohiko | |
dc.contributor.author | Hasse-Sousa, Mathias | |
dc.contributor.author | Henry, Chantal | |
dc.contributor.author | Hoffding, Lone | |
dc.contributor.author | Houenou, Josselin | |
dc.contributor.author | Imbesi, Massimiliano | |
dc.contributor.author | Isometsä, Erkki T. | |
dc.contributor.author | Ivkovic, Maja | |
dc.contributor.author | Janno, Sven | |
dc.contributor.author | Johnsen, Simon | |
dc.contributor.author | Kapczinski, Flávio | |
dc.contributor.author | Karakatsoulis, Gregory N. | |
dc.contributor.author | Kardell, Mathias | |
dc.contributor.author | Kessing, Lars Vedel | |
dc.contributor.author | Kim, Seong Jae | |
dc.contributor.author | König, Barbara | |
dc.contributor.author | Kot, Timur L. | |
dc.contributor.author | Koval, Michael | |
dc.contributor.author | Kunz, Mauricio | |
dc.contributor.author | Lafer, Beny | |
dc.contributor.author | Landén, Mikael | |
dc.contributor.author | Larsen, Erik R. | |
dc.contributor.author | Lenger, Melanie | |
dc.contributor.author | Licht, Rasmus W. | |
dc.contributor.author | Lopez-Jaramillo, Carlos | |
dc.contributor.author | MacKenzie, Alan | |
dc.contributor.author | Madsen, Helle Østergaard | |
dc.contributor.author | Madsen, Simone Alberte Kongstad A. | |
dc.contributor.author | Mahadevan, Jayant | |
dc.contributor.author | Mahardika, Agustine | |
dc.contributor.author | Manchia, Mirko | |
dc.contributor.author | Marsh, Wendy | |
dc.contributor.author | Martinez-Cengotitabengoa, Monica | |
dc.contributor.author | Martini, Julia | |
dc.contributor.author | Martiny, Klaus | |
dc.contributor.author | Mashima, Yuki | |
dc.contributor.author | McLoughlin, Declan M. | |
dc.contributor.author | Meesters, Ybe | |
dc.contributor.author | Melle, Ingrid | |
dc.contributor.author | Meza-Urzúa, Fátima | |
dc.contributor.author | Mikolas, Pavol | |
dc.contributor.author | Mok, Yee Ming | |
dc.contributor.author | Monteith, Scott | |
dc.contributor.author | Moorthy, Muthukumaran | |
dc.contributor.author | Morken, Gunnar | |
dc.contributor.author | Mosca, Enrica | |
dc.contributor.author | Mozzhegorov, Anton A. | |
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dc.contributor.author | Nadella, Ravi K. | |
dc.contributor.author | Nakanotani, Takako | |
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dc.contributor.author | O’Donovan, Claire | |
dc.contributor.author | Omrani, Adel | |
dc.contributor.author | Osher, Yamima | |
dc.contributor.author | Ouali, Uta | |
dc.contributor.author | Pantovic-Stefanovic, Maja | |
dc.contributor.author | Pariwatcharakul, Pornjira | |
dc.contributor.author | Petite, Joanne | |
dc.contributor.author | Petzold, Johannes | |
dc.contributor.author | Pfennig, Andrea | |
dc.contributor.author | Ruiz, Yolanda Pica | |
dc.contributor.author | Pinna, Marco | |
dc.contributor.author | Pompili, Maurizio | |
dc.contributor.author | Porter, Richard J. | |
dc.contributor.author | Quiroz, Danilo | |
dc.contributor.author | Rabelo-da-Ponte, Francisco Diego | |
dc.contributor.author | Ramesar, Raj | |
dc.contributor.author | Rasgon, Natalie | |
dc.contributor.author | Ratta-apha, Woraphat | |
dc.contributor.author | Ratzenhofer, Michaela | |
dc.contributor.author | Redahan, Maria | |
dc.contributor.author | Reddy, M.S. | |
dc.contributor.author | Reif, Andreas | |
dc.contributor.author | Reininghaus, Eva Z. | |
dc.contributor.author | Richards, Jenny Gringer | |
dc.contributor.author | Ritter, Philipp | |
dc.contributor.author | Rybakowski, Janusz K. | |
dc.contributor.author | Sathyaputri, Leela | |
dc.contributor.author | Scippa, Angela M. | |
dc.contributor.author | Simhandl, Christian | |
dc.contributor.author | Smith, Daniel | |
dc.contributor.author | Smith, José | |
dc.contributor.author | Stackhouse, Paul W. | |
dc.contributor.author | Stein, Dan J. | |
dc.contributor.author | Stilwell, Kellen | |
dc.contributor.author | Strejilevich, Sergio | |
dc.contributor.author | Su, Kuan-Pin | |
dc.contributor.author | Subramaniam, Mythily | |
dc.contributor.author | Sulaiman, Ahmad Hatim | |
dc.contributor.author | Suominen, Kirsi | |
dc.contributor.author | Tanra, Andi J. | |
dc.contributor.author | Tatebayashi, Yoshitaka | |
dc.contributor.author | Teh, Wen Lin | |
dc.contributor.author | Tondo, Leonardo | |
dc.contributor.author | Torrent, Carla | |
dc.contributor.author | Tuinstra, Daniel | |
dc.contributor.author | Uchida, Takahito | |
dc.contributor.author | Vaaler, Arne Einar | |
dc.contributor.author | Vieta, Eduard | |
dc.contributor.author | Viswanath, Biju | |
dc.contributor.author | Yoldi-Negrete, Maria | |
dc.contributor.author | Yalcinkaya, Oguz Kaan | |
dc.contributor.author | Young, Allan H. | |
dc.contributor.author | Zgueb, Yosra | |
dc.contributor.author | Whybrow, Peter C. | |
dc.date.accessioned | 2023-10-20T11:38:49Z | |
dc.date.available | 2023-10-20T11:38:49Z | |
dc.date.created | 2023-07-07T13:34:49Z | |
dc.date.issued | 2023 | |
dc.identifier.citation | International journal of bipolar disorders. 2023, 11 (1), . | en_US |
dc.identifier.issn | 2194-7511 | |
dc.identifier.uri | https://hdl.handle.net/11250/3097791 | |
dc.description.abstract | Background
Sunlight contains ultraviolet B (UVB) radiation that triggers the production of vitamin D by skin. Vitamin D has widespread effects on brain function in both developing and adult brains. However, many people live at latitudes (about > 40 N or S) that do not receive enough UVB in winter to produce vitamin D. This exploratory study investigated the association between the age of onset of bipolar I disorder and the threshold for UVB sufficient for vitamin D production in a large global sample.
Methods
Data for 6972 patients with bipolar I disorder were obtained at 75 collection sites in 41 countries in both hemispheres. The best model to assess the relation between the threshold for UVB sufficient for vitamin D production and age of onset included 1 or more months below the threshold, family history of mood disorders, and birth cohort. All coefficients estimated at P ≤ 0.001.
Results
The 6972 patients had an onset in 582 locations in 70 countries, with a mean age of onset of 25.6 years. Of the onset locations, 34.0% had at least 1 month below the threshold for UVB sufficient for vitamin D production. The age of onset at locations with 1 or more months of less than or equal to the threshold for UVB was 1.66 years younger.
Conclusion
UVB and vitamin D may have an important influence on the development of bipolar disorder. Study limitations included a lack of data on patient vitamin D levels, lifestyles, or supplement use. More study of the impacts of UVB and vitamin D in bipolar disorder is needed to evaluate this supposition. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Springer | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder | en_US |
dc.title.alternative | Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.source.pagenumber | 0 | en_US |
dc.source.volume | 11 | en_US |
dc.source.journal | International journal of bipolar disorders | en_US |
dc.source.issue | 1 | en_US |
dc.identifier.doi | 10.1186/s40345-023-00303-w | |
dc.identifier.cristin | 2161442 | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |