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dc.contributor.authorAune, Dagfinn
dc.contributor.authorSnekvik, Ingrid
dc.contributor.authorSchlesinger, Sabrina
dc.contributor.authorNorat, Teresa
dc.contributor.authorRiboli, Elio
dc.contributor.authorVatten, Lars Johan
dc.identifier.citationEuropean Journal of Epidemiology (EJE). 2018, 33 (12), 1163-1178.en_US
dc.description.abstractGreater body mass index (BMI) has been associated with increased risk of psoriasis in case–control and cross-sectional studies, however, the evidence from prospective studies has been limited. We conducted a systematic review and dose–response meta-analysis of different adiposity measures and the risk of psoriasis to provide a more robust summary of the evidence based on data from prospective studies. PubMed and Embase databases were searched for relevant studies up to August 8th 2017. Summary relative risks (RRs) and 95% confidence intervals (CIs) were calculated using a random effects model. The summary relative risk (RR) for a 5 unit increment in BMI was 1.19 (95% CI 1.10–1.28, I2 = 83%, n = 7). The association appeared to be stronger at higher compared to lower levels of BMI, pnonlinearity < 0.0001, and the lowest risk was observed at a BMI around 20. The summary RR was 1.24 (95% CI 1.17–1.31, I2 = 0%, pheterogeneity = 0.72, n = 3) per 10 cm increase in waist circumference, 1.37 (95% CI 1.23–1.53, I2 = 0%, pheterogeneity = 0.93, n = 3) per 0.1 unit increase in waist-to-hip ratio, and 1.11 (95% CI 1.07–1.16, I2 = 47%, pheterogeneity = 0.15, n = 3) per 5 kg of weight gain. Adiposity as measured by BMI, waist circumference, waist-to-hip ratio, and weight gain is associated with increased risk of psoriasis.en_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.subjectBody mass indexen_US
dc.titleBody mass index, abdominal fatness, weight gain and the risk of psoriasis: a systematic review and dose–response meta-analysis of prospective studiesen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.subject.nsiVDP::Dermatologi og venerologi: 753en_US
dc.subject.nsiVDP::Dermatology and venereology: 753en_US
dc.source.journalEuropean Journal of Epidemiology (EJE)en_US
dc.description.localcodeOpen AccessThis article is distributed under the terms of the CreativeCommons Attribution 4.0 International License (, which permits unrestricted use, dis-tribution, and reproduction in any medium, provided you giveappropriate credit to the original author(s) and the source, provide alink to the Creative Commons license, and indicate if changes weremadeen_US

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