Blar i Publikasjoner fra CRIStin - NTNU på tidsskrift "Scientific Reports"
Viser treff 1-20 av 357
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3D Maps of Mineral Composition and Hydroxyapatite Orientation in Fossil Bone Samples Obtained by X-ray Diffraction Computed Tomography
(Journal article; Peer reviewed, 2018)Whether hydroxyapatite (HA) orientation in fossilised bone samples can be non-destructively retrieved and used to determine the arrangement of the bone matrix and the location of muscle attachments (entheses), is a question ... -
5-hydroxymethylcytosine marks mammalian origins acting as a barrier to replication
(Journal article; Peer reviewed, 2019)In most mammalian cells, DNA replication occurs once, and only once between cell divisions. Replication initiation is a highly regulated process with redundant mechanisms that prevent errant initiation events. In lower ... -
A behavioral task with more opportunities for memory acquisition promotes the survival of new neurons in the adult dentate gyrus
(Journal article; Peer reviewed, 2018)It has been suggested that the dentate gyrus, particularly its new neurons generated via adult neurogenesis, is involved in memory acquisition and recall. Here, we trained rats in two types of Morris water maze tasks that ... -
A CRISPR/Cas9 system adapted for gene editing in marine algae
(Journal article; Peer reviewed, 2016)Here we report that the CRISPR/Cas9 technology can be used to efficiently generate stable targeted gene mutations in microalgae, using the marine diatom Phaeodactylum tricornutum as a model species. Our vector design opens ... -
A global-wide search for sexual dimorphism of glomeruli in the antennal lobe of female and male Helicoverpa armigera
(Journal article; Peer reviewed, 2016)By using immunostaining and three-dimensional reconstruction, the anatomical organization of the antennal lobe glomeruli of the female cotton bollworm Helicoverpa armigera was investigated. Eighty-one glomeruli were ... -
A nano-silicate material with exceptional capacity for CO2 capture and storage at room temperature
(Journal article; Peer reviewed, 2018)In order to mitigate climate change driven by the observed high levels of carbon dioxide (CO2) in the atmosphere, many micro and nano-porous materials are being investigated for CO2 selectivity, capture and storage (CCS) ... -
A novel role for pigment genes in the stress response in rainbow trout (Oncorhynchus mykiss)
(Journal article; Peer reviewed, 2016)In many vertebrate species visible melanin-based pigmentation patterns correlate with high stress- and disease-resistance, but proximate mechanisms for this trait association remain enigmatic. Here we show that a missense ... -
A prospective three-year follow-up study on the clinical significance of anti-neuronal antibodies in acute psychiatric disorders
(Peer reviewed; Journal article, 2019)The clinical significance of anti-neuronal antibodies for psychiatric disorders is controversial. We investigated if a positive anti-neuronal antibody status at admission to acute psychiatric inpatient care was associated ... -
A sex-inducing pheromone triggers cell cycle arrest and mate attraction in the diatom Seminavis robusta
(Journal article; Peer reviewed, 2016)Although sexual reproduction is believed to play a major role in the high diversification rates and species richness of diatoms, a mechanistic understanding of diatom life cycle control is virtually lacking. Diatom sexual ... -
Abdominal adipose tissue and liver fat imaging in very low birth weight adults born preterm: birth cohort with sibling-controls
(Peer reviewed; Journal article, 2022)Preterm birth at very low birth weight (VLBW, < 1500 g) is associated with an accumulation of cardiovascular and metabolic risk factors from childhood at least to middle age. Small-scale studies suggest that this could ... -
Accurate determination of marker location within whole-brain microscopy images
(Journal article; Peer reviewed, 2022) -
Action Representation in the Mouse Parieto-Frontal Network
(Peer reviewed; Journal article, 2020)The posterior parietal cortex (PPC) and frontal motor areas comprise a cortical network supporting goal-directed behaviour, with functions including sensorimotor transformations and decision making. In primates, this network ... -
Acute effects of high intensity training on cardiac function: a pilot study comparing subjects with type 2 diabetes to healthy controls
(Peer reviewed; Journal article, 2022)This study evaluated acute cardiac stress after a high-intensity interval training session in patients with type 2 diabetes (T2D) versus healthy controls. High intensity aerobic exercise was performed by 4 × 4-min intervals ... -
Adaptation, psychometric properties and factor structure of the Spanish Quality in Psychiatric Care-Outpatient Staff (QPC-OPS) instrument
(Peer reviewed; Journal article, 2022)Quality of care is a multidimensional concept that should include the perspectives of all parties involved. There are few instruments with adequate psychometric properties for the assessment of the quality of psychiatric ... -
Adaptor Template Oligo-Mediated Sequencing (ATOM-Seq) is a new ultra-sensitive UMI-based NGS library preparation technology for use with cfDNA and cfRNA
(Peer reviewed; Journal article, 2021)Liquid biopsy testing utilising Next Generation Sequencing (NGS) is rapidly moving towards clinical adoption for personalised oncology. However, before NGS can fulfil its potential any novel testing approach must identify ... -
Additive manufacturing of laminar flow cells for single-molecule experiments
(Journal article; Peer reviewed, 2019)A microfluidic laminar flow cell (LFC) forms an indispensable component in single-molecule experiments, enabling different substances to be delivered directly to the point under observation and thereby tightly controlling ... -
Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality
(Peer reviewed; Journal article, 2021)Erythropoietin producing hepatocellular (Eph) receptors and their membrane-bound ligands ephrins are variably expressed in epithelial cancers, with context-dependent implications to both tumor-promoting and -suppressive ... -
An orthogonal system for heterologous expression of actinobacterial lasso peptides in Streptomyces hosts
(Journal article; Peer reviewed, 2018)Lasso peptides are ribosomally synthesized and post-translationally modified peptides produced by bacteria. They are characterized by an unusual lariat-knot structure. Targeted genome scanning revealed a wide diversity of ... -
Anaerobic digestion of pig manure supernatant at high ammonia concentrations characterized by high abundances of Methanosaeta and non-euryarchaeotal archaea
(Journal article; Peer reviewed, 2017)We examined the effect of ammonium and temperature on methane production in high rate upflow anaerobic sludge bed reactors treating pig manure supernatant. We operated four reactors at two ammonium concentrations (‘low’ ... -
Ancient acquisition of "alginate utilization loci" by human gut microbiota
(Journal article; Peer reviewed, 2018)In bacteria from the phylum Bacteroidetes, the genes coding for enzymes involved in polysaccharide degradation are often colocalized and coregulated in so-called “polysaccharide utilization loci” (PULs). PULs dedicated to ...