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dc.contributor.authorHikmat, Omar
dc.contributor.authorVederhus, Bente Johanne
dc.contributor.authorBenestad, Merete Roineland
dc.contributor.authorEngeset, Ida Malen E.
dc.contributor.authorKlingenberg, Claus
dc.contributor.authorRasmussen, Magnhild
dc.contributor.authorTallaksen, Chantal
dc.contributor.authorBrodtkorb, Eylert
dc.contributor.authorElgen, Irene Bircow
dc.contributor.authorBindoff, Laurence
dc.date.accessioned2020-10-20T08:53:34Z
dc.date.available2020-10-20T08:53:34Z
dc.date.created2020-10-09T19:17:08Z
dc.date.issued2020
dc.identifier.citationMitochondrion (Amsterdam. Print). 2020, 55 95-99.en_US
dc.identifier.issn1567-7249
dc.identifier.urihttps://hdl.handle.net/11250/2683818
dc.description.abstractWe aimed to assess the impact of POLG disease on mental health and quality of life in 15 patients using the Symptom Checklist-90-R (SCL-90-R) and Short-Form 36 Health Survey (RAND-36). We found increased scores in all nine subscales of SCL-90-R, particularly phobic anxiety, depression and somatization. Further, patients reported considerably lower scores in all RAND-36 domains. This study revealed a global decline in mental health and poor quality of life in patients with POLG disease and highlights the need for increased awareness and systematic assessment in order to improve their quality of life and mental health.en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleMental health and health related quality of life in mitochondrial POLG diseaseen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.source.pagenumber95-99en_US
dc.source.volume55en_US
dc.source.journalMitochondrion (Amsterdam. Print)en_US
dc.identifier.doi10.1016/j.mito.2020.09.005
dc.identifier.cristin1838583
dc.description.localcode© 2020 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license.en_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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