dc.contributor.author | Hikmat, Omar | |
dc.contributor.author | Vederhus, Bente Johanne | |
dc.contributor.author | Benestad, Merete Roineland | |
dc.contributor.author | Engeset, Ida Malen E. | |
dc.contributor.author | Klingenberg, Claus | |
dc.contributor.author | Rasmussen, Magnhild | |
dc.contributor.author | Tallaksen, Chantal | |
dc.contributor.author | Brodtkorb, Eylert | |
dc.contributor.author | Elgen, Irene Bircow | |
dc.contributor.author | Bindoff, Laurence | |
dc.date.accessioned | 2020-10-20T08:53:34Z | |
dc.date.available | 2020-10-20T08:53:34Z | |
dc.date.created | 2020-10-09T19:17:08Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Mitochondrion (Amsterdam. Print). 2020, 55 95-99. | en_US |
dc.identifier.issn | 1567-7249 | |
dc.identifier.uri | https://hdl.handle.net/11250/2683818 | |
dc.description.abstract | We aimed to assess the impact of POLG disease on mental health and quality of life in 15 patients using the Symptom Checklist-90-R (SCL-90-R) and Short-Form 36 Health Survey (RAND-36). We found increased scores in all nine subscales of SCL-90-R, particularly phobic anxiety, depression and somatization. Further, patients reported considerably lower scores in all RAND-36 domains. This study revealed a global decline in mental health and poor quality of life in patients with POLG disease and highlights the need for increased awareness and systematic assessment in order to improve their quality of life and mental health. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | Mental health and health related quality of life in mitochondrial POLG disease | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.source.pagenumber | 95-99 | en_US |
dc.source.volume | 55 | en_US |
dc.source.journal | Mitochondrion (Amsterdam. Print) | en_US |
dc.identifier.doi | 10.1016/j.mito.2020.09.005 | |
dc.identifier.cristin | 1838583 | |
dc.description.localcode | © 2020 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license. | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |