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dc.contributor.authorAlbatat, Mohammad
dc.contributor.authorBergsland, Jacob
dc.contributor.authorArevalo, Hermenegild
dc.contributor.authorOdland, Hans Henrik
dc.contributor.authorBose, Pritam
dc.contributor.authorHalvorsen, Per Steinar
dc.contributor.authorBalasingham, Ilangko
dc.date.accessioned2020-01-13T08:11:26Z
dc.date.available2020-01-13T08:11:26Z
dc.date.created2019-11-13T16:02:25Z
dc.date.issued2019
dc.identifier.citationAnnals of Biomedical Engineering. 2019, 1-21.nb_NO
dc.identifier.issn0090-6964
dc.identifier.urihttp://hdl.handle.net/11250/2635823
dc.description.abstractCardiacCardiacdisease is aleading cause of death worldwide. Disturbance in the conduction system of the heart may trigger or aggravate heart dysfunction, affecting the efficiency of the heart, and lead to heart failure or cardiac arrest. Patients mayrequire implantable cardiac rhythm management devices (ICRMDs) to maintain or restore the heart rhythm. ICRMDs have undergone important improvements, yet limitations still exist, presentingimportant technological challenges. Most ICRMDs consist of a subcutaneous control unit and intracardiac electrodes. The leads, which connect the electrodes to the control unit, are usually placed transvenously through the subclavian veins. Various locations inside the heart areusedfor placement of electrodes, depending on the specific condition. Some of the limitationsto effective pacemaker therapyare associated with placement and location of the leads. Various approaches have been developed to overcome these challenges, such as multi-site pacing and leadless solutions.This paper aims to review the state of the art for the selection of placement sites for pacemakers, implantable cardioverter defibrillator (ICD)and cardiac resynchronization therapy devices (CRT)devices and discuss potential technological advancements to improve the results of ICRMD-therapyincluding development av leadless technologynb_NO
dc.language.isoengnb_NO
dc.publisherSpringernb_NO
dc.titleTechnological and clinical challenges in lead placement for cardiac rhythm management devicesnb_NO
dc.typeOthersnb_NO
dc.description.versionacceptedVersionnb_NO
dc.source.pagenumber1-21nb_NO
dc.source.journalAnnals of Biomedical Engineeringnb_NO
dc.identifier.doi10.1007/s10439-019-02376-0
dc.identifier.cristin1747229
dc.description.localcodeThis is a post-peer-review, pre-copyedit version of an article. Locked until 1.10.2020 due to copyright restrictions. The final authenticated version is available online at: 10.1007/s10439-019-02376-0nb_NO
cristin.unitcode194,63,35,0
cristin.unitnameInstitutt for elektroniske systemer
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode1


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