Show simple item record

dc.contributor.authorDietz, Rune
dc.contributor.authorLetcher, Robert J.
dc.contributor.authorDesforges, Jean-Pierre
dc.contributor.authorEulaers, Igor
dc.contributor.authorSonne, Christian
dc.contributor.authorWilson, Simon
dc.contributor.authorAndersen-Ranberg, Emilie
dc.contributor.authorBasu, Niladri
dc.contributor.authorBarst, Benjamin D.
dc.contributor.authorBustnes, Jan Ove
dc.contributor.authorBytingsvik, Jenny
dc.contributor.authorCiesielski, Tomasz Maciej
dc.contributor.authorDrevnick, Paul E.
dc.contributor.authorGabrielsen, Geir W.
dc.contributor.authorHaarr, Ane
dc.contributor.authorHylland, Ketil
dc.contributor.authorJenssen, Bjørn Munro
dc.contributor.authorLevin, Milton
dc.contributor.authorMcKinney, Melissa A.
dc.contributor.authorNørregaard, Rasmus Dyrmose
dc.contributor.authorPedersen, Kathrine E.
dc.contributor.authorProvencher, Jennifer
dc.contributor.authorStyrishave, Bjarne
dc.contributor.authorTartu, Sabrina
dc.contributor.authorAars, Jon
dc.contributor.authorAckerman, Joshua T.
dc.contributor.authorRosing-Asvid, Aqqalu
dc.contributor.authorBarrett, Rob
dc.contributor.authorBignert, Anders
dc.contributor.authorBorn, Erik W
dc.contributor.authorBranigan, Marsha
dc.contributor.authorBraune, Birgit
dc.contributor.authorBryan, Colleen E
dc.contributor.authorDam, Maria
dc.contributor.authorEagles-Smith, Collin A.
dc.contributor.authorEvans, Marlene
dc.contributor.authorEvans, Thomas J.
dc.contributor.authorFisk, Aaron T.
dc.contributor.authorGamberg, Mary
dc.contributor.authorGustavson, Kim
dc.contributor.authorHartman, C. Alex
dc.contributor.authorHelander, Björn
dc.contributor.authorHerzog, Mark P.
dc.contributor.authorHoekstra, Paul F.
dc.contributor.authorHoude, Magali
dc.contributor.authorHoydal, Katrin
dc.contributor.authorJackson, Allyson K.
dc.contributor.authorKucklick, John
dc.contributor.authorLie, Elisabeth
dc.contributor.authorLoseto, Lisa
dc.contributor.authorMallory, Mark L.
dc.contributor.authorMiljeteig, Cecilie
dc.contributor.authorMosbech, Anders
dc.contributor.authorMuir, Derek C.G.
dc.contributor.authorNielsen, Sanna Túni
dc.contributor.authorPeacock, Elizabeth
dc.contributor.authorPedro, Sara
dc.contributor.authorPeterson, Sarah H.
dc.contributor.authorPolder, Anuschka
dc.contributor.authorRigét, Frank F.
dc.contributor.authorRoach, Pat
dc.contributor.authorSaunes, Halvor
dc.contributor.authorSinding, Mikkel Holger Strander
dc.contributor.authorSkåre, Janneche Utne
dc.contributor.authorSøndergaard, Jens
dc.contributor.authorStenson, Garry
dc.contributor.authorStern, Gary
dc.contributor.authorTreu, Gabriele
dc.contributor.authorSchuur, Stacy S.
dc.contributor.authorVíkingsson, Gísli Arnór
dc.identifier.citationScience of the Total Environment. 2019, 696:133792 1-40.nb_NO
dc.description.abstractSince the last Arctic Monitoring and Assessment Programme (AMAP) effort to review biological effects of the exposure to organohalogen compounds (OHCs) in Arctic biota, there has been a considerable number of new Arctic effect studies. Here, we provide an update on the state of the knowledge of OHC, and also include mercury, exposure and/or associated effects in key Arctic marine and terrestrial mammal and bird species as well as in fish by reviewing the literature published since the last AMAP assessment in 2010. We aimed at updating the knowledge of how single but also combined health effects are or can be associated to the exposure to single compounds or mixtures of OHCs. We also focussed on assessing both potential individual as well as population health impacts using population-specific exposure data post 2000. We have identified quantifiable effects on vitamin metabolism, immune functioning, thyroid and steroid hormone balances, oxidative stress, tissue pathology, and reproduction. As with the previous assessment, a wealth of documentation is available for biological effects in marine mammals and seabirds, and sentinel species such as the sledge dog and Arctic fox, but information for terrestrial vertebrates and fish remain scarce. While hormones and vitamins are thoroughly studied, oxidative stress, immunotoxic and reproductive effects need further investigation. Depending on the species and population, some OHCs and mercury tissue contaminant burdens post 2000 were observed to be high enough to exceed putative risk threshold levels that have been previously estimated for non-target species or populations outside the Arctic. In this assessment, we made use of risk quotient calculations to summarize the cumulative effects of different OHC classes and mercury for which critical body burdens can be estimated for wildlife across the Arctic. As our ultimate goal is to better predict or estimate the effects of OHCs and mercury in Arctic wildlife at the individual, population and ecosystem level, there remain numerous knowledge gaps on the biological effects of exposure in Arctic biota. These knowledge gaps include the establishment of concentration thresholds for individual compounds as well as for realistic cocktail mixtures that in fact indicate biologically relevant, and not statistically determined, health effects for specific species and subpopulations. Finally, we provide future perspectives on understanding Arctic wildlife health using new in vivo, in vitro, and in silico techniques, and provide case studies on multiple stressors to show that future assessments would benefit from significant efforts to integrate human health, wildlife ecology and retrospective and forecasting aspects into assessing the biological effects of OHC and mercury exposure in Arctic wildlife and fish.nb_NO
dc.rightsNavngivelse 4.0 Internasjonal*
dc.titleCurrent state of knowledge on biological effects from contaminants on arctic wildlife and fishnb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.source.journalScience of the Total Environmentnb_NO
dc.description.localcode© 2019 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (
cristin.unitnameInstitutt for biologi

Files in this item


This item appears in the following Collection(s)

Show simple item record

Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal