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dc.contributor.authorDoan, Thanh Pierre
dc.contributor.authorDonate Lagartos, Maria Jose
dc.contributor.authorNilssen, Eirik Stamland
dc.contributor.authorOhara, Shinya
dc.contributor.authorWitter, Menno
dc.date.accessioned2019-10-24T08:23:04Z
dc.date.available2019-10-24T08:23:04Z
dc.date.created2019-10-14T22:17:28Z
dc.date.issued2019
dc.identifier.citationCell reports. 2019, 29 (3), 617-627.nb_NO
dc.identifier.issn2211-1247
dc.identifier.urihttp://hdl.handle.net/11250/2624058
dc.description.abstractThe current model of the organization of the medial temporal lobe (MTL) episodic memory system assumes that two functionally different “where” and “what” pathways enter MTL as parallel parahippocampal cortex (PHC)-medial entorhinal cortex (MEC) and perirhinal cortex (PER)-lateral entorhinal cortex (LEC) streams, respectively. With the use of tract tracing and in vitro electrophysiological recordings, we show that, in the rat LEC, all main principal neuron types in layer II receive convergent inputs from PER and postrhinal cortex (POR), homologous to PHC in primates. Projections to MEC from POR are much less prominent than previously assumed. These findings thus challenge the prevailing concept that LEC and MEC are defined by different inputs from the PER and PHC/POR, respectively. Our findings point to LEC as the main parahippocampal multimodal integrative structure whose unique set of external sensory-derived inputs allows its network to represent a continuously fluctuating extrinsic environment.nb_NO
dc.language.isoengnb_NO
dc.publisherElseviernb_NO
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleConvergent projections from perirhinal and postrhinal cortices suggest a multisensory nature of lateral but not medial entorhinal cortexnb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionpublishedVersionnb_NO
dc.source.pagenumber617-627nb_NO
dc.source.volume29nb_NO
dc.source.journalCell reportsnb_NO
dc.source.issue3nb_NO
dc.identifier.doi10.1016/j.celrep.2019.09.005
dc.identifier.cristin1737009
dc.description.localcode© 2019 The Authors. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).nb_NO
cristin.unitcode194,65,60,0
cristin.unitnameKavliinstitutt for nevrovitenskap
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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