dc.contributor.advisor | Hoff, Bård Helge | |
dc.contributor.advisor | Han, Jin | |
dc.contributor.author | Bekkevard, Pål Unnerud | |
dc.date.accessioned | 2019-09-11T10:36:17Z | |
dc.date.created | 2015-06-11 | |
dc.date.issued | 2015 | |
dc.identifier | ntnudaim:12362 | |
dc.identifier.uri | http://hdl.handle.net/11250/2615664 | |
dc.description.abstract | A series of 7H-pyrrolo- and thieno[2,3-d]pyrimidine based compounds have been synthesized and tested for Janus kinase 2 (JAK2) inhibition, as part of a fragment-based approach to obtaining information on structure-activity relationships.
At the same time, improvements have been achieved regarding pyrrole protecting
groups and amination of fused pyrimidines. | en |
dc.language | eng | |
dc.publisher | NTNU | |
dc.subject | Industriell kjemi og bioteknologi, Kjemi | en |
dc.title | Synthesis of Pyrrolopyrimidines for Investigation of JAK2 Inhibition | en |
dc.type | Master thesis | en |
dc.source.pagenumber | 175 | |
dc.contributor.department | Norges teknisk-naturvitenskapelige universitet, Fakultet for naturvitenskap,Institutt for kjemi | nb_NO |
dc.date.embargoenddate | 10000-01-01 | |