Blar i St. Olavs hospital på tidsskrift "Free Radical Biology & Medicine"
Viser treff 1-3 av 3
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Age- and sex-dependent effects of DNA glycosylase Neil3 on amyloid pathology, adult neurogenesis, and memory in a mouse model of Alzheimer's disease
(Peer reviewed; Journal article, 2022)Oxidative stress generating DNA damage has been shown to be a key characteristic in Alzheimer's disease (AD). However, how it affects the pathogenesis of AD is not yet fully understood. Neil3 is a DNA glycosylase initiating ... -
DNA glycosylase Neil2 contributes to genomic responses in the spleen during clinical prion disease
(Peer reviewed; Journal article, 2020)The DNA glycosylase Neil2 is a member of the base excision repair (BER) family of enzymes, which are important for repair of oxidative DNA damage. Specifically, Neil2 participates in repair of oxidized bases in single-stranded ... -
NRF2 drives an oxidative stress response predictive of breast cancer
(Peer reviewed; Journal article, 2022)Many breast cancer patients are diagnosed with small, well-differentiated, hormone receptor-positive tumors. Risk of relapse is not easily identified in these patients, resulting in overtreatment. To identify metastasis-related ...