• A new acoustic coupling fluid with ability to reduce ultrasound imaging artefacts in brain tumour surgery - a phase I study 

      Unsgård, Geirmund; Sagberg, Lisa Millgård; Muller, Sebastien; Selbekk, Tormod (Journal article; Peer reviewed, 2019)
      Background Anovel acoustic coupling fluid (ACF), with the potential to reduce surgically induced image artefacts during intraoperative ultrasound imaging in brain tumour surgery, has been evaluated with respect to image ...
    • Advancements in predicting outcomes in patients with glioma: a surgical perspective 

      Jakola, Asgeir S; Sagberg, Lisa Millgård; Gulati, Sasha; Solheim, Ole (Peer reviewed; Journal article, 2020)
      Introduction: Diffuse glioma is a challenging neurosurgical entity. Although surgery does not provide a cure, it may greatly influence survival, brain function, and quality of life. Surgical treatment is by nature highly ...
    • Animal study assessing safety of an acoustic coupling fluid that holds the potential to avoid surgically induced artifacts in 3D ultrasound guided operations 

      Jakola, Asgeir S; Jørgensen, Arve; Selbekk, Tormod; Michler, Ralf-Peter; Solheim, Ole; Torp, Sverre Helge; Sagberg, Lisa Millgård; Aadahl, Petter; Unsgård, Geirmund (Journal article; Peer reviewed, 2014)
      Background Use of ultrasound in brain tumor surgery is common. The difference in attenuation between brain and isotonic saline may cause artifacts that degrade the ultrasound images, potentially affecting resection grades ...
    • Are there predilection sites for intracranial meningioma? A population-based atlas 

      Hosainey, Sayied Abdol Mohieb; Bouget, David; Reinertsen, Ingerid; Sagberg, Lisa Millgård; Torp, Sverre Helge; Jakola, Asgeir Store; Solheim, Ole (Peer reviewed; Journal article, 2021)
      Meningioma is the most common benign intracranial tumor and is believed to arise from arachnoid cap cells of arachnoid granulations. We sought to develop a population-based atlas from pre-treatment MRIs to explore the ...
    • Brain infarctions after glioma surgery: prevalence, radiological characteristics and risk factors 

      Strand, Per Sveino; Berntsen, Erik Magnus; Fyllingen, Even Hovig; Sagberg, Lisa Millgård; Reinertsen, Ingerid; Gulati, Sasha; Bouget, David; Solheim, Ole (Peer reviewed; Journal article, 2021)
      Background: Prevalence, radiological characteristics, and risk factors for peritumoral infarctions after glioma surgery are not much studied. In this study, we assessed shape, volume, and prevalence of peritumoral infarctions ...
    • Does preoperative health-related quality of life predict survival in high-grade glioma patients? – a prospective study 

      Haraldseide, Lisa Marie; Jakola, Asgeir S; Solheim, Ole; Sagberg, Lisa Millgård (Peer reviewed; Journal article, 2019)
      Purpose: To explore if preoperative patient-reported health-related quality of life (HRQoL) provides additional prognostic value as a supplement to other preoperatively known clinical factors in patients with high-grade ...
    • Glioblastoma Surgery Imaging-Reporting and Data System: Validation and Performance of the Automated Segmentation Task 

      Bouget, David Nicolas Jean-Marie; Eijgelaar, Roelant; Pedersen, André; Kommers, Ivar; Ardon, Hilko; Barkhof, Frederik; Bello, Lorenzo; Berger, Mitchel S.; Nibali, Marco Conti; Furtner, Julia; Fyllingen, Even Hovig; Hervey-Jumper, Shawn; Idema, Albert J. S.; Kiesel, Barbara; Kloet, Alfred; Mandonnet, Emmanuel; Müller, Domenique M. J.; Robe, Pierre; Rossi, Marco; Sagberg, Lisa Millgård; Sciortino, Tommaso; van den Brink, Wimar A.; Wagemakers, Michiel; Widhalm, Georg; Witte, Marnix G.; Zwinderman, Aeilko H.; Reinertsen, Ingerid; Hamer, Philip C De Witt; Solheim, Ole (Journal article; Peer reviewed, 2021)
      For patients with presumed glioblastoma, essential tumor characteristics are determined from preoperative MR images to optimize the treatment strategy. This procedure is time-consuming and subjective, if performed by crude ...
    • Glioblastoma Surgery Imaging—Reporting and Data System: Standardized Reporting of Tumor Volume, Location, and Resectability Based on Automated Segmentations 

      Kommers, Ivar; Bouget, David Nicolas Jean-Marie; Pedersen, André; Eijgelaar, Roelant; Ardon, Hilko; Barkhof, Frederik; Bello, Lorenzo; Berger, Mitchel S.; Nibali, Marco Conti; Furtner, Julia; Fyllingen, Even Hovig; Hervey-Jumper, Shawn; Idema, Albert J. S.; Kiesel, Barbara; Kloet, Alfred; Mandonnet, Emmanuel; Müller, Domenique M. J.; Robe, Pierre; Rossi, Marco; Sagberg, Lisa Millgård; Sciortino, Tommaso; van den Brink, Wimar A.; Wagemakers, Michiel; Widhalm, Georg; Witte, Marnix G.; Zwinderman, Aeilko H.; Reinertsen, Ingerid; Solheim, Ole; De Witt Hamer, Philip C. (Peer reviewed; Journal article, 2021)
      Treatment decisions for patients with presumed glioblastoma are based on tumor characteristics available from a preoperative MR scan. Tumor characteristics, including volume, location, and resectability, are often estimated ...
    • How well do neurosurgeons predict survival in patients with high-grade glioma? 

      Sagberg, Lisa Millgård; Jakola, Asgeir S.; Reinertsen, Ingerid; Solheim, Ole (Journal article; Peer reviewed, 2021)
      Due to the lack of reliable prognostic tools, prognostication and surgical decisions largely rely on the neurosurgeons’ clinical prediction skills. The aim of this study was to assess the accuracy of neurosurgeons’ prediction ...
    • Impact of transsphenoidal surgery for pituitary adenomas on overall health-related quality of life: a longitudinal cohort study 

      Sommerfelt, Hanne; Sagberg, Lisa Millgård; Solheim, Ole (Peer reviewed; Journal article, 2019)
      Background: Previous studies show a moderate improvement in health-related quality of life (HRQoL) following transsphenoidal surgery for pituitary adenomas, but no consistent predictors of HRQoL outcome have been identified. ...
    • Perioperative fatigue in patients with diffuse glioma 

      Schei, Stine; Solheim, Ole; Jakola, Asgeir S; Sagberg, Lisa Millgård (Peer reviewed; Journal article, 2020)
      Purpose Few studies have assessed fatigue in relation to glioma surgery. The purpose of this study was to explore the prevalence of pre- and postoperative high fatigue, perioperative changes, and factors associated with ...
    • Primary versus recurrent surgery for glioblastoma-a prospective cohort study 

      Rubin, Maja Chava; Sagberg, Lisa Millgård; Jakola, Asgeir S; Solheim, Ole (Peer reviewed; Journal article, 2020)
      Background: There is currently limited evidence for surgery in recurrent glioblastoma (GBM). Our aim was to compare primary and recurrent surgeries, regarding changes in perioperative, generic health-related quality of ...
    • Spatial distribution of malignant transformation in patients with low-grade glioma 

      Jakola, Asgeir S; Bouget, David Nicolas Jean-Marie; Reinertsen, Ingerid; Skjulsvik, Anne Jarstein; Sagberg, Lisa Millgård; Bø, Hans Kristian; Gulati, Sasha; Sjåvik, Kristin; Solheim, Ole (Journal article; Peer reviewed, 2020)
      Background Malignant transformation represents the natural evolution of diffuse low-grade gliomas (LGG). This is a catastrophic event, causing neurocognitive symptoms, intensified treatment and premature death. However, ...
    • Survival of glioblastoma in relation to tumor location: a statistical tumor atlas of a population-based cohort 

      Fyllingen, Even Hovig; Bø, Lars Eirik; Reinertsen, Ingerid; Jakola, Asgeir Store; Sagberg, Lisa Millgård; Berntsen, Erik Magnus; Salvesen, Øyvind; Solheim, Ole (Peer reviewed; Journal article, 2021)
      Purpose Previous studies on the effect of tumor location on overall survival in glioblastoma have found conflicting results. Based on statistical maps, we sought to explore the effect of tumor location on overall survival ...
    • What is the current clinico-radiological diagnostic accuracy for intracranial tumours? 

      Majewska, Paulina Luiza; Sagberg, Lisa Millgård; Reinertsen, Ingerid; Gulati, Sasha; Jakola, Asgeir Store; Solheim, Ole (Peer reviewed; Journal article, 2021)
      Objective To determine the diagnostic accuracy of routine clinico-radiological workup for a population-based selection of intracranial tumours. Methods In this prospective cohort study, we included consecutive adult ...