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dc.contributor.authorLi, Xiaoying
dc.contributor.authorWang, Lei
dc.contributor.authorAsimakopoulos, Alexandros
dc.contributor.authorSun, Hongwen
dc.contributor.authorZhao, Zhen
dc.contributor.authorZhang, Junjie
dc.contributor.authorZhang, Lu
dc.contributor.authorWang, Qi
dc.date.accessioned2019-03-22T09:03:03Z
dc.date.available2019-03-22T09:03:03Z
dc.date.created2019-01-17T11:42:04Z
dc.date.issued2018
dc.identifier.citationChemosphere. 2018, 199 524-530.nb_NO
dc.identifier.issn0045-6535
dc.identifier.urihttp://hdl.handle.net/11250/2591232
dc.description.abstractBenzotriazoles (BTRs) and benzothiazoles (BTHs) are two groups of heterocyclic compounds that are widely detected in the environment. In this study, the levels of BTRs and BTHs in 79 paired maternal urine and amniotic fluid samples from Tianjin were investigated. BTRs were detected in most maternal urine samples, with a median concentration of ∑BTRs of 0.88 ng/mL. BTH was detected in all maternal urine samples, with a median concentration of 1.35 ng/mL. Tolyltriazole (TTR, i.e., the sum of 4-methyl-1H-benzotriazole and 5-methyl-1H-benzotriazole) and BTH were detected in amniotic fluid with detection rates (DRs) > 50% and median concentrations of 0.026 and 0.61 ng/mL, respectively. The median concentrations of ∑BTRs and ∑BTHs (0.026 and 0.72 ng/mL) in amniotic fluid were lower than those in maternal urine. The median ratio of the ∑BTRs concentrations in amniotic fluid to those in maternal urine was 0.030, with a range of 0.017–1.82, while the median value for TTR, BTH and 5-Cl-1H-BTR were 0.12, 0.46, and 1.43, respectively. This indicates greater distribution in fetal excretion to 5-Cl-1H-BTR than BTH and TTR. The concentrations of ∑BTRs in maternal urine exhibited significant distribution differences (p < 0.05) with respect to some parameters, including maternal age, gestational week, gravidity, parity, and fetal weight. However, no significant correlations (p > 0.05) were observed in target compounds in amniotic fluid for the epidemiological factors assessed herein. The geometric means of the estimated daily intakes were 1.15 (0.052–7.66) μg/day and 1.92 (0.027–6.64) μg/day for ∑BTRs and ∑BTHs in present study, which are lower than those reported in previous study.nb_NO
dc.language.isoengnb_NO
dc.publisherElseviernb_NO
dc.titleBenzotriazoles and benzothiazoles in paired maternal urine and amniotic fluid samples from Tianjin, Chinanb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionpublishedVersionnb_NO
dc.source.pagenumber524-530nb_NO
dc.source.volume199nb_NO
dc.source.journalChemospherenb_NO
dc.identifier.doi10.1016/j.chemosphere.2018.02.076
dc.identifier.cristin1659176
dc.description.localcodeThis article will not be available due to copyright restrictions (c) 2018 by Elseviernb_NO
cristin.unitcode194,66,25,0
cristin.unitnameInstitutt for kjemi
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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