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dc.contributor.authorEid, Hege Rasmussen
dc.contributor.authorRosness, Tor Atle
dc.contributor.authorBosnes, Ole
dc.contributor.authorSalvesen, Øyvind
dc.contributor.authorKnutli, Marlen
dc.contributor.authorStordal, Eystein
dc.identifier.citationDementia and geriatric cognitive disorders extra. 2018, (8), 414-425.nb_NO
dc.description.abstractBackground: The roles of both anxiety and depression as risk factors for frontotemporal dementia (FTD) and Alzheimer’s disease (AD) have not been previously investigated together. Objective: To study anxiety and depression as independent risk factors for FTD and AD. Methods: Eighty-four patients with FTD and 556 patients with AD were compared with 117 cognitively healthy (CH), elderly individuals. Both cases and controls were participants in the second Health Study of Nord-Trøndelag (HUNT2) from 1995 to 1997, in which depression and anxiety were assessed with the Hospital Anxiety and Depression Scale (HADS). Results: Significant associations were found between anxiety and FTD and between depression and AD. A significantly increased risk of developing FTD was observed in patients who had reported anxiety on the HADS (p = 0.017) (odds ratio [OR]: 2.947, 95% confidence interval [CI]: 1.209–7.158) and a significantly increased risk of developing AD was observed in patients who had reported depression on the HADS (p = 0.016) (OR: 4.389, 95% CI: 1.311–14.690). Conclusion: Our study findings suggest that anxiety and depression may play different roles as risk factors for FTD and AD.nb_NO
dc.publisherKarger Publishers Open Accessnb_NO
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internasjonal*
dc.titleAnxiety and Depression as Risk Factors in Frontotemporal Dementia and Alzheimers Disease: The HUNT Studynb_NO
dc.title.alternativeAnxiety and Depression as Risk Factors in Frontotemporal Dementia and Alzheimers Disease: The HUNT Studynb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.source.journalDementia and geriatric cognitive disorders extranb_NO
dc.description.localcode© 2018 The Author(s) Published by S. Karger AG, Basel. This article is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).nb_NO
cristin.unitnameInstitutt for psykisk helse
cristin.unitnameMH fakultetsadministrasjon
cristin.unitnameInstitutt for sirkulasjon og bildediagnostikk

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Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal