Vis enkel innførsel

dc.contributor.authorJacobsen, Elisabeth Egholm
dc.contributor.authorAnthonsen, Thorleif
dc.date.accessioned2018-04-13T08:53:50Z
dc.date.available2018-04-13T08:53:50Z
dc.date.created2017-10-03T20:22:22Z
dc.date.issued2017
dc.identifier.citationTrends in Organic Chemistry. 2017, 18 71-83.nb_NO
dc.identifier.issn0972-4362
dc.identifier.urihttp://hdl.handle.net/11250/2494030
dc.description.abstractKinetic resolution catalysed by lipases is a well suited strategy in order to provide enantiopure organic compounds. Factors affecting the enantiomeric ratio, the E-value, such as substrate structure, temperature effects, effects due to reaction media, significance of acyl donor, water activity of organic solvents and immobilisation of the catalyst, are discussed. Allosteric effects caused by chemicals in the reaction medium, which may influence the action of the enzyme catalyst are briefly discussed. Dynamic kinetic resolution and in situ stereoinversion methods that can be used to obtain more than 50% yield of a kinetic resolution are also discussed. The determination of the absolute configuration of the produced enantiomers based on enzyme preferences is an important issue.nb_NO
dc.language.isoengnb_NO
dc.publisherResearch Trendsnb_NO
dc.titleSingle Enantiomers from Racemates. Lipase catalysed Kinetic Resolution of Secondary Alcohols. In situ Stereoinversionnb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionacceptedVersionnb_NO
dc.source.pagenumber71-83nb_NO
dc.source.volume18nb_NO
dc.source.journalTrends in Organic Chemistrynb_NO
dc.identifier.cristin1502005
dc.description.localcodeThis article will not be available due to copyright restrictions (c) 2017 by Research Trendsnb_NO
cristin.unitcode194,66,25,0
cristin.unitnameInstitutt for kjemi
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode1


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel