dc.contributor.author | Mjønes, Patricia | |
dc.contributor.author | Nordrum, Ivar Skjåk | |
dc.contributor.author | Qvigstad, Gunnar | |
dc.contributor.author | Sørdal, Øystein Finset | |
dc.contributor.author | Rian, Liselotte Linnea Mårtensson | |
dc.contributor.author | Waldum, Helge | |
dc.date.accessioned | 2018-02-05T12:45:58Z | |
dc.date.available | 2018-02-05T12:45:58Z | |
dc.date.created | 2017-02-27T09:02:21Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 2017, 125 (3), 213-222. | nb_NO |
dc.identifier.issn | 0903-465X | |
dc.identifier.uri | http://hdl.handle.net/11250/2482667 | |
dc.description.abstract | The aim of the study was to investigate the expression of erythropoietin and neuroendocrine markers in clear cell renal cell carcinoma (CCRCC). We retrospectively reviewed the medical records and re-evaluated histopathological specimens of 33 patients with CCRCC and compared with those of 11 cases of non-CCRCC. All patients were treated with a partial or radical nephrectomy at St. Olavs Hospital, Trondheim University Hospital, between 2010 and 2016. Thirty-three patients who were diagnosed with CCRCC had a total of 35 tumours, where 34 of the tumours were CCRCC and one was papillary adenoma. Thirty-three (97%) of 34 CCRCCs were positive for erythropoietin, and the same 33 (97%) tumours demonstrated strong expression for neuron-specific enolase (NSE). Two (6%) of 34 CCRCCs had a positive reaction for synaptophysin, and three (9%) of 34 were positive for CD56. Erythropoietin and NSE were negative in non-CCRCCs, and chromogranin A was negative in all tumours. The above findings suggest that there is a strong association between CCRCC and the expression of erythropoietin and NSE. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | Wiley | nb_NO |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/deed.no | * |
dc.title | Expression of erythropoietin and neuroendocrine markers in clear cell renal cell carcinoma | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | nb_NO |
dc.description.version | publishedVersion | nb_NO |
dc.source.pagenumber | 213-222 | nb_NO |
dc.source.volume | 125 | nb_NO |
dc.source.journal | APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum | nb_NO |
dc.source.issue | 3 | nb_NO |
dc.identifier.doi | 10.1111/apm.12654 | |
dc.identifier.cristin | 1454058 | |
dc.description.localcode | © 2017 The Authors APMIS published by John Wiley & Sons Ltd on behalf of Scandinavian Societies for Medical Microbiology and Pathology. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License | nb_NO |
cristin.unitcode | 194,65,15,0 | |
cristin.unitname | Institutt for klinisk og molekylær medisin | |
cristin.ispublished | true | |
cristin.fulltext | preprint | |
cristin.qualitycode | 1 | |