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Computer-based video analysis identifies infants with absence of fidgety movements

Støen, Ragnhild; Songstad, Nils Thomas; Silberg, Inger Elisabeth; Fjørtoft, Toril Synnøve Larsso; Jensenius, Alexander Refsum; Adde, Lars
Journal article, Peer reviewed
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Manuscript_revised_uploaded+Cristin.pdf (181.4Kb)
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http://hdl.handle.net/11250/2482660
Utgivelsesdato
2017
Metadata
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  • Institutt for klinisk og molekylær medisin [2120]
  • Publikasjoner fra CRIStin - NTNU [21889]
Originalversjon
Pediatric Research. 2017, 82 (4), 665-670.   10.1038/pr.2017.121
Sammendrag
Background: Absence of fidgety movements (FMs) at 3 months’ corrected age is a strong predictor of cerebral palsy (CP) in high-risk infants. This study evaluates the association between computer-based video analysis and the temporal organization of FMs assessed with the General Movement Assessment (GMA). Methods: Infants were eligible for this prospective cohort study if referred to a high-risk follow-up program in a participating hospital. Video recordings taken at 10–15 weeks post term age were used for GMA and computer-based analysis. The variation of the spatial center of motion, derived from differences between subsequent video frames, was used for quantitative analysis. Results: Of 241 recordings from 150 infants, 48 (24.1%) were classified with absence of FMs or sporadic FMs using the GMA. The variation of the spatial center of motion (CSD) during a recording was significantly lower in infants with normal (0.320; 95% confidence interval (CI) 0.309, 0.330) vs. absence of or sporadic (0.380; 95% CI 0.361, 0.398) FMs (P<0.001). A triage model with CSD thresholds chosen for sensitivity of 90% and specificity of 80% gave a 40% referral rate for GMA. Conclusion: Quantitative video analysis during the FMs’ period can be used to triage infants at high risk of CP to early intervention or observational GMA.
Utgiver
Nature Publishing Group
Tidsskrift
Pediatric Research

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