dc.contributor.author | Rogstad, Tonje Waterloo | |
dc.contributor.author | Sonne, Christian | |
dc.contributor.author | Villanger, Gro Dehli | |
dc.contributor.author | Ahlstrøm, Øystein | |
dc.contributor.author | Fuglei, Eva | |
dc.contributor.author | Muir, Derek C.G. | |
dc.contributor.author | Jørgensen, Even Hjalmar | |
dc.contributor.author | Jenssen, Bjørn Munro | |
dc.date.accessioned | 2017-12-21T13:29:58Z | |
dc.date.available | 2017-12-21T13:29:58Z | |
dc.date.created | 2017-01-16T12:59:45Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Environmental Research. 2017, 154 284-290. | nb_NO |
dc.identifier.issn | 0013-9351 | |
dc.identifier.uri | http://hdl.handle.net/11250/2473547 | |
dc.description.abstract | The aim of the present study was to investigate the relationships and effects of oral POP exposure on retinol (vitamin A), α-tocopherol (vitamin E), thyroid hormones and testosterone in emaciated adult farmed Arctic foxes. Eight brother-pairs were exposed to either a diet containing naturally POP-contaminated minke whale blubber (Balaenoptera acutorostrata) (n=8), or a control diet containing pig (Sus scrofa) fat as the primary fat source (n=8) for 22 months. In the whale blubber containing feed the ∑POPs concentration was 802 ng/g w.w. and it was 24 ng/g w.w. in control feed. The liver mass was significantly higher and the ratio of FT4 (free thyroxine):FT3 (free triiodothyronine) was significantly lower in the POP exposed group as compared to the control group given feed with pig fat (both p<0.05). The exposed group revealed lower plasma and liver concentrations of α-tocopherol compared to the control group (both p<0.05). These results indicate that plasma FT4:FT3 ratio and plasma and liver α-tocopherol are valuable biomarker endpoints for chronic oral POP exposure in wild Arctic foxes. Based on this we suggest that plasma FT4:FT3 ratio and plasma and liver α-tocopherol are valuable biomarker endpoints for chronic POP exposure in wildlife Arctic foxes and that these perturbations may affect their health status. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | Elsevier | nb_NO |
dc.title | Concentrations of vitamin A, E, thyroid and testosterone hormones in blood plasma and tissues from emaciated adult male Arctic foxes (Vulpes lagopus) dietary exposed to persistent organic pollutants (POPs) | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | nb_NO |
dc.description.version | publishedVersion | nb_NO |
dc.source.pagenumber | 284-290 | nb_NO |
dc.source.volume | 154 | nb_NO |
dc.source.journal | Environmental Research | nb_NO |
dc.identifier.doi | 10.1016/j.envres.2017.01.017 | |
dc.identifier.cristin | 1428225 | |
dc.description.localcode | This article will not be available due to copyright restrictions (c) 2017 by Elsevier | nb_NO |
cristin.unitcode | 194,0,0,0 | |
cristin.unitcode | 194,66,10,0 | |
cristin.unitname | Norges teknisk-naturvitenskapelige universitet | |
cristin.unitname | Institutt for biologi | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 2 | |