dc.contributor.author | Michelsen, Brigitte | |
dc.contributor.author | Diamantopoulos, Andreas P | |
dc.contributor.author | Soldal, Dag | |
dc.contributor.author | Hammer, Hilde Berner | |
dc.contributor.author | Kavanaugh, Arthur | |
dc.contributor.author | Haugeberg, Glenn | |
dc.date.accessioned | 2017-12-14T10:05:27Z | |
dc.date.available | 2017-12-14T10:05:27Z | |
dc.date.created | 2017-10-23T12:59:47Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | RMD Open. 2017, 3: e000486. | nb_NO |
dc.identifier.issn | 2056-5933 | |
dc.identifier.uri | http://hdl.handle.net/11250/2471621 | |
dc.description.abstract | Objective
To compare clinical and ultrasonographic (US) evaluation of Achilles enthesitis in patients with psoriatic arthritis (PsA).
Methods
The Achilles insertion of outpatients with PsA was examined by clinical assessment of tenderness and US evaluation of (1) inflammatory activity (defined as the presence of power Doppler signal, tendon thickening and/or hypoechogenicity) and (2) structural damage (defined as the presence of erosions, calcifications and/ or enthesophytes). Univariate and multivariate logistic regression analyses were performed0.4 to explore the associations between clinical characteristics and US scores.
Results
282 Achilles tendons in 141 patients with PsA were assessed. Mean (SD) age was 52.4 (10.2) years, disease duration 9.5 (6.6) years and 50.4% were females. Palpatory tenderness was found in 88 (31.2%), USverified inflammatory activity in 46 (16.3%) and structural damage in 148 (52.5%) of the Achilles. Total US scores, as well as their components, were similar for patients with and without palpatory tenderness. None of the clinical characteristics were associated with inflammatory activity. Age, body mass index (BMI), regular physical exercise and current use of biological disease-modifying antirheumatic drugs (bDMARDs) were associated with structural damage.
Conclusion
There appears to be a lack of association between clinical and US signs of Achilles enthesitis in PsA. Age, BMI, regular physical exercise and current use of bDMARDs were associated with structural damage on US. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | BMJ Publishing Group | nb_NO |
dc.rights | Navngivelse-Ikkekommersiell 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/deed.no | * |
dc.title | Achilles enthesitis defined by ultrasound is not associated with clinical enthesitis in patients with psoriatic arthritis | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | nb_NO |
dc.description.version | publishedVersion | nb_NO |
dc.source.volume | 3 | nb_NO |
dc.source.journal | RMD Open | nb_NO |
dc.identifier.doi | 10.1136/rmdopen-2017-000486 | |
dc.identifier.cristin | 1506818 | |
dc.description.localcode | © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ | nb_NO |
cristin.unitcode | 194,65,30,0 | |
cristin.unitname | Institutt for nevromedisin og bevegelsesvitenskap | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |