dc.contributor.author | Borgan, Eldrid | |
dc.contributor.author | Lindholm, Evita Maria | |
dc.contributor.author | Moestue, Siver Andreas | |
dc.contributor.author | Mælandsmo, Gunhild | |
dc.contributor.author | Lingjærde, Ole Christian | |
dc.contributor.author | Gribbestad, Ingrid S | |
dc.contributor.author | Børresen-Dale, Anne-Lise | |
dc.contributor.author | Engebråten, Olav | |
dc.contributor.author | Sørlie, Therese | |
dc.date.accessioned | 2017-11-29T10:22:08Z | |
dc.date.available | 2017-11-29T10:22:08Z | |
dc.date.created | 2012-11-20T08:36:21Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Molecular Oncology. 2013, 7 (1), 130-142. | nb_NO |
dc.identifier.issn | 1574-7891 | |
dc.identifier.uri | http://hdl.handle.net/11250/2468489 | |
dc.description.abstract | Antiangiogenic therapy with bevacizumab has shown varying results in breast cancer clinical trials. Identifying robust biomarkers for selecting patients who may benefit from such treatment and for monitoring response is important for the future use of bevacizumab. Two established xenograft models representing basal-like and luminal-like breast cancer were used to study bevacizumab treatment response on the metabolic and gene expression levels. Tumor samples were obtained from mice treated with bevacizumab, doxorubicin or a combination of the two drugs, and high resolution magic angle spinning magnetic resonance spectroscopy and gene expression microarray analysis was performed. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | Elsevier | nb_NO |
dc.title | Subtype-specific response to bevacizumab is reflected in the metabolome and transcriptome of breast cancer xenografts | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | nb_NO |
dc.description.version | publishedVersion | nb_NO |
dc.source.pagenumber | 130-142 | nb_NO |
dc.source.volume | 7 | nb_NO |
dc.source.journal | Molecular Oncology | nb_NO |
dc.source.issue | 1 | nb_NO |
dc.identifier.doi | 10.1016/j.molonc.2012.10.005 | |
dc.identifier.cristin | 963385 | |
dc.relation.project | Norges forskningsråd: 193375 | nb_NO |
dc.relation.project | Norges forskningsråd: 193387 | nb_NO |
dc.description.localcode | © 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved. Open Access article available at http://dx.doi.org/10.1016/j.molonc.2012.10.005 | nb_NO |
cristin.unitcode | 194,65,25,0 | |
cristin.unitname | Institutt for sirkulasjon og bildediagnostikk | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |