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Onconeural Antibodies in Acute Psychiatric Inpatient Care

Sæther, Sverre Georg; Schou, Morten Brix; Stoecker, W; Teegen, B; Borowski, K; Vaaler, Arne Einar; Kondziella, Daniel; Reitan, Solveig Merete Klæbo
Journal article, Peer reviewed
Accepted version
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URI
http://hdl.handle.net/11250/2466554
Date
2016
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  • Institutt for nevromedisin og bevegelsesvitenskap [2957]
  • Institutt for psykisk helse [1153]
  • Publikasjoner fra CRIStin - NTNU [34842]
Original version
The Journal of Neuropsychiatry and Clinical Neurosciences. 2016, 29 (1), 74-76.   10.1176/appi.neuropsych.16050110
Abstract
Paraneoplastic neurological disorders associated with onconeural antibodies often appear with neuropsychiatric symptoms. To study the prevalence of onconeural antibodies in patients admitted to acute psychiatric inpatient care, the serum of 585 such patients was tested for antibodies targeting MOG, GLRA1B, DPPX, GRM1, GRM5, DNER, Yo, ZIC4, GAD67, amphiphysin, CV2, Hu, Ri, Ma2, and recoverin. Only one sample was positive (antirecoverin IgG). The present findings suggest that serum onconeural antibody positivity is rare among patients acutely admitted for inpatient psychiatric care. The clinical implications of this finding are discussed.
Publisher
American Psychiatric Publishing
Journal
The Journal of Neuropsychiatry and Clinical Neurosciences

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