Browsing Institutt for bioingeniørfag by Author "Lehti, Kaisa Irene"
Now showing items 1-3 of 3
-
The drug efficacy testing in 3D cultures platform identifies effective drugs for ovarian cancer patients
Åkerlund, Emma; Gudoityte, Greta; Moussaud-Lamodière, Elisabeth; Lind, Olina; Bwanika, Henri Colyn; Lehti, Kaisa Irene; Salehi, Sahar; Carlson, Joseph; Wallin, Emelie; Fernebro, Josefin; Östling, Päivi; Kallioniemi, Olli; Joneborg, Ulrika; Seashore-Ludlow, Brinton (Peer reviewed; Journal article, 2023)Most patients with advanced ovarian cancer (OC) relapse and progress despite systemic therapy, pointing to the need for improved and tailored therapy options. Functional precision medicine can help to identify effective ... -
MMP14 expression and collagen remodelling support uterine leiomyosarcoma aggressiveness
Gonzalez-Molina, Jordi; Hahn, Paula; Falcão, Raul Maia; Gultekin, Okan; Kokaraki, Georgia; Zanfagnin, Valentina; Braz Petta, Tirzah; Lehti, Kaisa Irene; Carlson, Joseph W. (Peer reviewed; Journal article, 2023)Fibrillar collagen deposition, stiffness and downstream signalling support the development of leiomyomas (LMs), common benign mesenchymal tumours of the uterus, and are associated with aggressiveness in multiple carcinomas. ... -
Tumour Suppressor Neuron Navigator 3 and Matrix Metalloproteinase 14 are Co-expressed in Most Melanomas but Downregulated in Thick Tumours
Bugaeva, Olga; Maliniemi, Pilvi; Prestvik, Wenche Slettahjell; Leivo, Eeva; Kluger, Nicolas; Salava, Alexander; Virtanen, Sanna; Jäntti, Kirsi; Saksela, Olli; Lehti, Kaisa Irene; Kujala, Paula; Krohn, Kaj; Ranki, Annamari (Journal article; Peer reviewed, 2023)