Now showing items 14741-14760 of 38747

    • Functional metabolic interactions of human neuron-astrocyte 3D in vitro networks 

      Simao, Daniel; Terrasso, Ana P; Teixeira, Ana P; Brito, Catarina; Sonnewald, Ursula; Alves, Paula M. (Peer reviewed; Journal article, 2016)
      The generation of human neural tissue-like 3D structures holds great promise for disease modeling, drug discovery and regenerative medicine strategies. Promoting the establishment of complex cell-cell interactions, 3D ...
    • Functional network topography of the medial entorhinal cortex 

      Obenhaus, Horst-Andreas; Zong, Weijian; Jacobsen, R. Irene; Rose, Tobias; Donato, Flavio; Chen, Liangyi; Cheng, Heping; Bonhoeffer, Tobias; Moser, May-Britt; Moser, Edvard Ingjald (Journal article; Peer reviewed, 2022)
      The medial entorhinal cortex (MEC) creates a map of local space,based on thefiring patterns of grid, head-direction (HD), border,and object-vector (OV) cells. How these cell types are organizedanatomically is debated. ...
    • Functional organization of the hippocampal longitudinal axis 

      Strange, B; Witter, Menno; Lein, Ed S.; Moser, Edvard Ingjald (Journal article; Peer reviewed, 2014)
      The precise functional role of the hippocampus remains a topic of much debate. The dominant view is that the dorsal (or posterior) hippocampus is implicated in memory and spatial navigation and the ventral (or anterior) ...
    • Functional outcome and survival following spontaneous intracerebral hemorrhage: A retrospective population-based study 

      Øie, Lise Rystad; Madsbu, Mattis Aleksander; Solheim, Ole; Jakola, Asgeir Store; Giannadakis, Charalampis; Vorhaug, Anders; Padayachy, Llewellyn; Jensberg, Heidi; Dodick, David W.; Salvesen, Øyvind; Gulati, Sasha (Journal article; Peer reviewed, 2018)
      Background Accurate and reliable clinical and radiological predictors of intracerebral hemorrhage (ICH) outcomes are needed to optimize treatment of ICH. The aim of this study was to investigate functional outcome and ...
    • Functional precision cancer medicine: drug sensitivity screening enabled by cell culture models 

      Flobak, Åsmund; Skånland, Sigrid S; Hovig, Eivind; Tasken, Kjetil; Russnes, Hege Elisabeth Giercksky (Peer reviewed; Journal article, 2022)
      Functional precision medicine is a new, emerging area that can guide cancer treatment by capturing information from direct perturbations of tumor-derived, living cells, such as by drug sensitivity screening. Precision ...
    • Functional profiling reveals altered metabolic activity in divers’ oral microbiota during commercial heliox saturation diving 

      Monnoyer, Roxane; Eftedal, Ingrid; Hjelde, Astrid; Deb, Sanjoy Kumar; Haugum, Kjersti; Lautridou, Jacky (Peer reviewed; Journal article, 2021)
      Background: The extreme environment in saturation diving affects all life forms, including the bacteria that reside on human skin and mucosa. The oral cavity alone is home to hundreds of different bacteria. In this study, ...
    • Functional properties of habenular neurons are determined by developmental stage and sequential neurogenesis 

      Fore, Stephanie Liesbeth; Acuna Hinrichsen, Francisca Daniela; Mutlu, Aytac Kadir; Bartoszek-Kandler, Ewelina Magdalena; Serneels, Bram; Faturos, Nicholas Guy; Chau, Khac Thanh Phong; Cosacak, Mehmet Ilyas; Diaz Verdugo, Carmen; Palumbo, Fabrizio; Ringers, Christa; Jurisch-Yaksi, Nathalie; Kizil, Caghan; Yaksi, Emre (Peer reviewed; Journal article, 2020)
      The developing brain undergoes drastic alterations. Here, we investigated developmental changes in the habenula, a brain region that mediates behavioral flexibility during learning, social interactions, and aversive ...
    • Functional properties of habenular neurons are determined by developmental stage and sequential neurogenesis 

      Fore, Stephanie Liesbeth; Acuna Hinrichsen, Francisca Daniela; Mutlu, Aytac Kadir; Bartoszek-Kandler, Ewelina Magdalena; Chau, Khac Thanh Phong; Diaz Verdugo, Carmen; Palumbo, Fabrizio; Ringers, Christa; Jurisch-Yaksi, Nathalie; Yaksi, Emre; Serneels, Bram (Peer reviewed; Journal article, 2020)
      The developing brain undergoes drastic alterations. Here, we investigated developmental changes in the habenula, a brain region that mediates behavioral flexibility during learning, social interactions, and aversive ...
    • Functional properties of habenular neurons are determined by developmental stage and sequential neurogenesis. 

      Forè, Stèphanie; Hinrichsen, Francisca; Mutlu, Kadir; Bartoszek, Ewelina; Yaksi, Emre (Peer reviewed; Journal article, 2020)
      The developing brain undergoes drastic alterations. Here, we investigated developmental changes in the habenula, a brain region that mediates behavioral flexibility during learning, social interactions, and aversive ...
    • The Functional Properties of Mg–Zn–X Biodegradable Magnesium Alloys 

      Merson, Dmitry; Brilevsky, Alexander; Myagkikh, Pavel; Tarkova, Alexandra; Prokhorikhin, Alexei; Kretov, Evgeni; Frolova, Tatyana; Vinogradov, Alexey (Journal article; Peer reviewed, 2020)
      The implantation of metallic devices in orthopaedic surgical procedures and coronary angioplasty is associated with the risk of various adverse events: (i) mechanical (premature failure), (ii) chemo-mechanical (corrosion ...
    • Functional properties of stellate cells in medial entorhinal cortex layer II 

      Rowland, David Clayton; Obenhaus, Horst-Andreas; Skytøen, Emilie; Zhang, Qiangwei; Kentros, Clifford; Moser, Edvard Ingjald; Moser, May-Britt (Journal article; Peer reviewed, 2018)
      Layer II of the medial entorhinal cortex (MEC) contains two principal cell types: pyramidal cells and stellate cells. Accumulating evidence suggests that these two cell types have distinct molecular profiles, physiological ...
    • Functional Role of PilA in Iron Acquisition in the Cyanobacterium Synechocystis sp. PCC 6803 

      Lamb, Jacob Joseph; Hill, Ryan; Eaton-Rye, Julian J.; Hohmann-Marriott, Martin Frank (Journal article; Peer reviewed, 2014)
      Cyanobacteria require large quantities of iron to maintain their photosynthetic machinery; however, in most environments iron is present in the form of insoluble iron oxides. Whether cyanobacteria can utilize these sources ...
    • Functional roles of Aves class-specific cis-regulatory elements on macroevolution of bird-specific features 

      Seki, Ryohei; Li, Caí; Fang, Qi; Hayashi, Shinichi; Egawa, Shiro; Hu, Jiang; Xu, Luohao; Pan, Hailin; Kondo, Mao; Sato, Tomohiko; Matsubara, Haruka; Kamiyama, Namiko; Kitajima, Keiichi; Saito, Daisuke; Liu, Yang; Gilbert, Marcus Thomas Pius; Zhou, Qi; Xu, Xing; Shiroishi, Toshihiko; Irie, Naoki; Tamura, Koji; Zhang, Guojie (Journal article; Peer reviewed, 2017)
      Unlike microevolutionary processes, little is known about the genetic basis of macroevolutionary processes. One of these magnificent examples is the transition from non-avian dinosaurs to birds that has created numerous ...
    • Functional Safety of Railway Signaling Systems: Performance Requirements and Evaluation Methods 

      Zhang, Aibo; Jiang, Lei; Xie, Min; Kassa, Elias; Liu, Yiliu (Chapter, 2021)
      Signaling is fundamental to the safe operation of the railway, ensuring that trains are spaced safely apart and conflicting movements are avoided. Railway signals are `traffic light' devices, which tell a train driver if ...
    • Functional Toll-like receptors in primary first-trimester trophoblasts 

      Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Leknes, Ann-Helen; Gundersen, Astrid; Skei, Bente; Vikdal, Anne Jorunn; Ryan, Liv; Steinkjer, Bjørg; Myklebost, Merete; Langaas, Mette; Austgulen, Rigmor; Iversen, Ann-Charlotte (Journal article; Peer reviewed, 2014)
      Toll-like receptors (TLRs) are an important part of the body's danger response system and crucial for initiating inflammation in response to cellular stress, tissue damage, and infections. Proper placental development is ...
    • Functional traits of alpine plant communities show long-term resistance to changing herbivore densities 

      Vuorinen, Katariina Elsa Maria; Austrheim, Gunnar; Mysterud, Atle; Gya, Ragnhild; Vandvik, Vigdis; Grytnes, John Arvid; Speed, James David Mervyn (Peer reviewed; Journal article, 2021)
      Herbivores shape vegetation by suppressing certain plant species while benefitting others. By thus modifying plant species functional composition, herbivores affect carbon cycling, albedo, vegetation structure and species' ...
    • Functional Writing in the Primary Years: Protocol for a Mixed-Methods Writing Intervention Study 

      Skar, Gustaf Bernhard Uno; Aasen, Arne Johannes; Jølle, Lennart (Peer reviewed; Journal article, 2020)
      This protocol article describes the project Functional Writing in the Primary Years, which received funding in late 2018 and was started in August 2019. The Functional Writing in Primary School (FUS) project aims to increase ...
    • Functionalization of a clustered TiO2 nanotubular surface with platelet derived growth factor-BB covalent modification enhances osteogenic differentiation of bone marrow mesenchymal stem cells 

      Ma, Qianli; Jiang, Nan; Shuang, Liang; Fulin, Chen; Liang, Fang; Xian, Wang; Jinjin, Wang; Lihua, Chen (Peer reviewed; Journal article, 2020)
      A multitude of micro- and nano-surface structures have been developed to improve the clinical performance of endosseous titanium (Ti) implants. However, most of these surface structures only simulate the topographic elements ...
    • Functionalized carbon nanotube-encapsulated magnesium-based nanocomposites with outstanding mechanical and biological properties as load-bearing bone implants 

      Abazari, Somayeh; Shamsipur, Ali; Bakhsheshi-Rad, Hamid Reza; Berto, Filippo (Peer reviewed; Journal article, 2022)
      Magnesium (Mg)-based composites have recently been studied as biodegradable material for the fabrication of orthopedic implants. Nevertheless, in physiological environments, proper mechanical properties and sufficient ...
    • Functionalized TiO2 nanoparticles by single-step hydrothermal synthesis: the role of the silane coupling agents 

      Dalod, Antoine Robert Marie; Henriksen, Lars; Grande, Tor; Einarsrud, Mari-Ann (Journal article; Peer reviewed, 2017)
      A simple, robust and versatile hydrothermal synthesis route to in situ functionalized TiO2 nanoparticles was developed using titanium(IV) isopropoxide as Ti-precursor and selected silane coupling agents (3-aminopropyltri ...