dc.contributor.author | Arpaia, Salvatore | |
dc.contributor.author | Birch, Andrew | |
dc.contributor.author | Chesson, Andrew | |
dc.contributor.author | duJardin, Patrick | |
dc.contributor.author | Løvik, Martinus | |
dc.contributor.author | Nielsen, Kaare Magne | |
dc.contributor.author | Sorteberg, Hilde-Gunn Opsahl | |
dc.date.accessioned | 2016-02-05T12:46:55Z | |
dc.date.accessioned | 2016-06-20T11:00:43Z | |
dc.date.available | 2016-02-05T12:46:55Z | |
dc.date.available | 2016-06-20T11:00:43Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | EFSA Journal 2015, 13(5):4083 | nb_NO |
dc.identifier.issn | 1831-4732 | |
dc.identifier.uri | http://hdl.handle.net/11250/2393221 | |
dc.description.abstract | Maize 5307 was developed by Agrobacterium tumefaciens-mediated transformation to express two proteins:
eCry3.1Ab, conferring resistance to certain coleopteran pests, and phosphomannose isomerase (PMI), used as
selection marker. The molecular characterisation showed relevant similarities between the amino acid sequence
of PMI and a known allergen, and between the amino acid sequence of eCry3.1Ab and a potential toxin. Some
agronomic and phenotypic differences between maize 5307 and its conventional counterpart were observed
(higher ‘heat units to 50 % pollen shed’, grain moisture, plant height, grain yield); however, the EFSA GMO
Panel considered that these do not give rise to food/feed or environmental safety concerns. No differences in the
compositional data requiring further safety assessment were identified. There were no concerns regarding the
potential toxicity and allergenicity of the PMI protein. The EFSA GMO Panel could not conclude on the safety
of the eCry3.1Ab protein due to the inadequate 28-day toxicity study provided. The outcome of a broiler feeding
study with maize 5307 was not assessed by the EFSA GMO Panel, due to study weaknesses. There are no
indications of an increased likelihood of the establishment and spread of feral maize plants. Interactions with the
biotic and abiotic environment were not considered to be a relevant issue. Risks associated with the unlikely but
theoretically possible horizontal gene transfer of recombinant genes from maize 5307 to bacteria were not
identified. The post-market environmental monitoring plan and reporting intervals are in line with the scope of
the application. In conclusion, in the absence of an appropriate assessment of eCry3.1Ab, the EFSA GMO Panel
is not in a position to complete its food/feed risk assessment of maize 5307. However, the EFSA GMO Panel
concludes that the maize 5307 is unlikely to have any adverse effect on the environment in the context of its
scope. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | European Food Safety Authority | nb_NO |
dc.title | Scientific Opinion on application (EFSA-GMO-DE-2011-95) for the placing on the market of genetically modified maize 5307 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 from Syngenta Crop Protection AG | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | nb_NO |
dc.date.updated | 2016-02-05T12:46:55Z | |
dc.source.volume | 13 | nb_NO |
dc.source.journal | EFSA Journal | nb_NO |
dc.source.issue | 5 | nb_NO |
dc.identifier.cristin | 1309812 | |
dc.description.localcode | © European Food Safety Authority, 2015. | nb_NO |