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dc.contributor.authorLupattelli, Angela
dc.contributor.authorSpigset, Olav
dc.contributor.authorTwigg, Michael J.
dc.contributor.authorZagorodnikova, Ksenia
dc.contributor.authorMårdby, Ann-Charlotte
dc.contributor.authorMoretti, Myla Emily
dc.contributor.authorDrozd, Mariola
dc.contributor.authorPanchaud, Alice
dc.contributor.authorHämeen-Anttila, Katri
dc.contributor.authorRieutord, Andre
dc.contributor.authorGjergia Jurasky, Romana
dc.contributor.authorOdalovic, Marina
dc.contributor.authorKennedy, Debra
dc.contributor.authorRudolf, Gorazd
dc.contributor.authorJuch, Herbert
dc.contributor.authorPassier, Anneke
dc.contributor.authorBjörnsdottir, Ingunn
dc.contributor.authorNordeng, Hedvig Marie Egeland
dc.date.accessioned2015-01-07T12:03:40Z
dc.date.accessioned2015-12-03T12:32:54Z
dc.date.available2015-01-07T12:03:40Z
dc.date.available2015-12-03T12:32:54Z
dc.date.issued2014
dc.identifier.citationBMJ Open 2014, 4(2)nb_NO
dc.identifier.issn2044-6055
dc.identifier.urihttp://hdl.handle.net/11250/2366722
dc.description.abstractObjectives: Intercountry comparability between studies on medication use in pregnancy is difficult due to dissimilarities in study design and methodology. This study aimed to examine patterns and factors associated with medications use in pregnancy from a multinational perspective, with emphasis on type of medication utilised and indication for use. Design: Cross-sectional, web-based study performed within the period from 1 October 2011 to 29 February 2012. Uniform collection of drug utilisation data was performed via an anonymous online questionnaire. Setting: Multinational study in Europe (Western, Northern and Eastern), North and South America and Australia. Participants: Pregnant women and new mothers with children less than 1 year of age. Primary and secondary outcome measures: Prevalence of and factors associated with medication use for acute/short-term illnesses, chronic/long-term disorders and over-the-counter (OTC) medication use. Results: The study population included 9459 women, of which 81.2% reported use of at least one medication (prescribed or OTC) during pregnancy. Overall, OTC medication use occurred in 66.9% of the pregnancies, whereas 68.4% and 17% of women reported use of at least one medication for treatment of acute/short-term illnesses and chronic/long-term disorders, respectively. The extent of self-reported medicated illnesses and types of medication used by indication varied across regions, especially in relation to urinary tract infections, depression or OTC nasal sprays. Women with higher age or lower educational level, housewives or women with an unplanned pregnancy were those most often reporting use of medication for chronic/long-term disorders. Immigrant women in Western (adjusted OR (aOR): 0.55, 95% CI 0.34 to 0.87) and Northern Europe (aOR: 0.50, 95% CI 0.31 to 0.83) were less likely to report use of medication for chronic/long-term disorders during pregnancy than non-immigrants. Conclusions: In this study, the majority of women in Europe, North America, South America and Australia used at least one medication during pregnancy. There was a substantial inter-region variability in the types of medication used.nb_NO
dc.language.isoengnb_NO
dc.publisherBMJ Publishing Groupnb_NO
dc.relation.urihttp://bmjopen.bmj.com/content/4/2/e004365.full.pdf+html
dc.titleMedication use in pregnancy: a cross-sectional, multinationalweb-based studynb_NO
dc.typeJournal articlenb_NO
dc.typePeer revieweden_GB
dc.date.updated2015-01-07T12:03:40Z
dc.subject.nsiVDP::Medisinske fag: 700::Helsefag: 800::Epidemiologi medisinsk og odontologisk statistikk: 803nb_NO
dc.subject.nsiVDP::Midical sciences: 700::Health sciences: 800::Epidemiology, medical and dental statistics: 803nb_NO
dc.source.volume4nb_NO
dc.source.journalBMJ Opennb_NO
dc.identifier.doi10.1136/bmjopen-2013-004365
dc.identifier.cristin1116052
dc.description.localcodeThis is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/nb_NO


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