Responsive Hydrogels for Label-Free Signal Transduction within Biosensors
Journal article, Peer reviewed
Permanent lenke
http://hdl.handle.net/11250/2360120Utgivelsesdato
2010Metadata
Vis full innførselSamlinger
- Institutt for fysikk [2646]
- Publikasjoner fra CRIStin - NTNU [36890]
Sammendrag
Hydrogels have found wide application in biosensors due to their versatile nature. This family of materials is applied in biosensing either to increase the loading capacity compared to two-dimensional surfaces, or to support biospecific hydrogel swelling occurring subsequent to specific recognition of an analyte. This review focuses on various principles underpinning the design of biospecific hydrogels acting through various molecular mechanisms in transducing the recognition event of label-free analytes. Towards this end, we describe several promising hydrogel systems that when combined with the appropriate readout platform and quantitative approach could lead to future real-life applications.