| dc.contributor.author | Yu, Qiang | |
| dc.contributor.author | Carlsen, Per Henning | |
| dc.date.accessioned | 2015-09-30T12:24:57Z | |
| dc.date.accessioned | 2015-11-06T15:17:46Z | |
| dc.date.available | 2015-09-30T12:24:57Z | |
| dc.date.available | 2015-11-06T15:17:46Z | |
| dc.date.issued | 2008 | |
| dc.identifier.citation | Molecules 2008, 13:701-715 | nb_NO |
| dc.identifier.issn | 1420-3049 | |
| dc.identifier.uri | http://hdl.handle.net/11250/2359654 | |
| dc.description.abstract | Water soluble homo-base polynucleotide analogues were synthesized in which
polyvinyl alcohol and partially phosphonated polyvinyl alcohol constituted the backbones,
onto which were grafted uracil or adenine via 1,3-dioxane spacers formed by acetal
formation with the 1,3-diol moieties in PVA. The resulting adenine-PVA polynucleotide
analogs exhibited hyperchromic effects, which was not the case for the corresponding
uracil compounds. Mixtures of the adenine- and aracil PVA-phosphate polynucleotide
analogs in solutions exhibited characteristic S-shaped UV-absorbance vs temperature and
melting curves with melting points at approximately 40 oC. | nb_NO |
| dc.language.iso | eng | nb_NO |
| dc.publisher | MDPI | nb_NO |
| dc.title | Synthesis of polynucleotide analogs containing a polyvinyl alcohol backbone | nb_NO |
| dc.type | Journal article | nb_NO |
| dc.type | Peer reviewed | en_GB |
| dc.date.updated | 2015-09-30T12:24:57Z | |
| dc.source.pagenumber | 701-715 | nb_NO |
| dc.source.volume | 13 | nb_NO |
| dc.source.journal | Molecules | nb_NO |
| dc.identifier.doi | 10.3390/molecules13030701 | |
| dc.identifier.cristin | 362744 | |
| dc.description.localcode | This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | nb_NO |
