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Enantioselective Synthesis of Homo-N-Nucleosides Containing a 1,4-Dioxane Sugar Analog

Yu, Qiang; Carlsen, Per Henning
Journal article, Peer reviewed
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URI
http://hdl.handle.net/11250/2359643
Date
2008
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  • Publikasjoner fra CRIStin - NTNU [20946]
Original version
Molecules 2008, 13(12):2962-2974   10.3390/molecules13122962
Abstract
A dioxane homo-sugar analog, (2S,5S)-and (2R,5S)-5-[(4S)-2,2-dimethyl-1,3-

dioxolan-4-yl]-2-iodomethyl-1,4-dioxane was prepared from (2R,3R)-dimethyl tartrate,

and further elaborated into the corresponding homo-N-nucleoside analogs by its reactions

with uracil and adenine, respectively.
Publisher
MDPI
Journal
Molecules

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